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Cancer Cell Biology

The Cancer Cell Biology (CCB) Program focuses on basic research investigating the complex biological networks in cells that are dysregulated in cancer, and the interactions between cells and their environment that impact cancer development and progression. Research in the CCB Program aims to:

  • Elucidate the role of cell intrinsic factors (including those regulating cancer metabolism, signal transduction, autophagy, cell death and cell cycle regulation) in cancer
  • Study the role of cell extrinsic factors (mechanical forces, inflammation, tumor immunology and tumor microenvironment) in tumor initiation and progression
  • Exploit cell biological mechanisms of tumor initiation and progression for the development of more effective and targeted therapeutics
  • Develop and provide new cell biological resources for the cancer research community

Members

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