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By interweaving nucleic acid scientists with clinicians dedicated to finding new cures, our goal is to create a new paradigm for organizing molecular research that enables the rapid application of new biological discoveries to solutions for unmet challenges in human health.
Anastasia Khvorova, PhD, the Remondi Family Chair in Biomedical Research and professor of RNA therapeutics, was awarded the Chancellor’s Medal for Distinguished Scholarship. As recipient of the award, Dr. Khvorova presented the plenary lecture at the UMass Chan research retreat.
Save the dates for June 22-24, 2022 for the 4th annual RNA Therapeutics Symposium. Inclusivity and family support awards are available!
ScienceLIVE is an educational science outreach program for Worcester area middle schools. We provide opportunities for students to engage with our diverse postdoctoral and graduate student trainees through interactive, exciting virtual and hands-on STEM activities.
Using a short, synthetic chain of chemically modified nucleotides engineered in the RNA Therapeutics Institute, Robert H. Brown Jr., DPhil, MD, Jonathan Watts, PhD, and colleagues suppressed mutant forms of an ALS gene known as C9ORF72 in a single-patient pilot study. C9ORF72 is the most common cause of familial amyotrophic lateral sclerosis (ALS) and familial frontotemporal dementia (FTD). Read more at UMass Med News, MassLIVE, and article, Suppression of mutant C9orf72 expression by a potent mixed backbone antisense oligonucleotide.
Meet Craig Mello, part of the RTI at UMass Chan, who was awarded the 2006 Nobel Prize in Physiology or Medicine, with Andrew Z. Fire, for the discovery of RNA interference. The discovery of RNAi has given scientists unprecedented opportunities to develop new life-saving therapies and advance our basic understanding of biology.
