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UMass Diabetes Center of Excellence Facilities & Partnerships

Under the co-direction of David M. Harlan, MD and Dale Greiner, PhD, the UMass DCOE fosters both clinical & basic diabetes research and brings together diabetes clinicians and investigators from all over the world.

The UMass Chan Medical School is consistently ranked by U.S. News & World Report as one of the leading medical schools in the nation for primary care education. UMass Chan Medical School & UMass Memorial Health collaborate towards one common goal: Better care for all people living with diabetes.    

Ambulatory Care Center  

Our pediatric and adult diabetes care clinics are located on the second floor of this state-of-the-art building.  Clinical and translational research also takes place in the ACC building.

 

 

 

 

 

 

 

The Albert Sherman Center
 

Most of the DCOE research labs are located on the 7th floor of this world-class 500,000 sqare foot facility. We're equipped with Immunospot, microplate and microarray readers, two flow cytometers (an Accuri 4-color bench top cytometer and a Beckman Coulter Cytomics FC-500), spectrophotometers, a luminometer, a Nanodrop, two Eppendorf Realplex real-time PCR machine, thermocyclers, gel imagers, MACS cell separation system, cryogenic cell/tissue storage, a Biorep 12-chamber islet perifusion system, and several cell culture facilities including biosafety cabinets with microscopes dedicated for sterile retrieval of selected cells and for dissection. In addition to routine microscopy and microscopes for live cell imaging (Nikon TIU series), our microscope suite includes inverted and upright Nikon Eclipse Ti-5 series microscopes for multiple fluorescent marker imaging. Microscopes are combined with NIS-Elements imaging software to support diverse image acquisition and analysis methods such as multi-dimensional time-lapse, multi-position acquisition, large image acquisition with stitching. Each scope is equipped with high-resolution black and white camera for fluorescent samples and additionally there's a high-resolution color camera for H&E samples on the upright scope.

Diabetes Collaborations and Partnerships

Under the auspices of the UMass Chan Medical School and UMass Memorial Health (plus affiliated colleagues and professional organizations in the community), the UMass Diabetes Center of Excellence (DCOE) partners with multiple clinical and research teams to provide the best potential treatment(s) for people living with diabetes.

The JDRF New England Research Collaborative

Five of our DCOE research labs are collaborating with Harvard Stem Cell Institute, The Jackson Laboratory, Joslin Diabetes Center, and Dana-Farber Cancer Institute to transplant stem cell (SC) derived beta-like cell clusters into our unique humanized mouse models to recreate and study the human disease unlike ever before. This collaborative research group is focused on understanding the autoimmune attack on beta cells in people living with type 1 diabetes, and using modern gene editing methods such as CRISPR, to make the cells inert or evasive to the autoimmune attack. The ultimate goal is to create therapies which can be scaled and eventually go into clinical trials, and ultimately cure diabetes. 

UMass Memorial Health 

We see more than 8000 patients each year. They receive the best diabetes treatments currently available, while we continue to develop better treatment therapies. Personalized care is provided to help with all aspects of diabetes management.

Community Diabetes Partnership Program

The UMass DCOE partners with hospitals throughout Central Massachusetts to help them provide comprehensive diabetes care within their communities. Our diabetes specialists work with clinicians at these local hospitals, including endocrinologists, nurse practitioners, certified diabetes educators and nutritionists.  The goal is to ensure that all people living with diabetes have all locally available resources. 

UMass DCOE Care in the Community

Henry Heywood Hospital in Gardner - Taylor Boudreau, NP 

Health Alliance Fitchburg Family Practice - Dr. Asem Ali & Brenden Howarth, MSN, RN, FNP-BC

Milford Regional Medical Center - Dr. Samir Malkani