World-Class Diabetes Research and Care
Research to Prevent and Cure Diabetes at UMass Chan Medical School

Under the co-direction of Dale L. Greiner, PhD, and David M. Harlan, MD, the goal of the UMass Diabetes Center of Excellence (DCOE) at UMass Chan Medical School is to prevent and cure diabetes. Our DCOE research faculty is gaining new knowledge of the disease by studying human tissues and human cells inside of our unique biological models, which mimic the human immune system. Understanding what causes diabetes will allow us to develop effective therapies, and ultimately find the cure.
Research Strategies
DCOE News
Total: displaying 5 out of 140 results-
Friday, April 22, 2022Read more
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Thursday, March 31, 2022
Identifying Genes Linked to the Risk of Developing Type 2 Diabetes
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Thursday, March 24, 2022
Type 2 Diabetes Researcher Spotlight: Sarah Nicoloro
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Wednesday, March 16, 2022
Guertin Lab Article in Trends in Biochemical Sciences Describes Multi-omics Era of Adipocyte Insulin Signaling and Metabolism Research
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Tuesday, March 08, 2022
Two Medical Students Created an Elective Course Teaching In-Depth Diabetes Management and Care
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Thursday, March 03, 2022
Type 1 Diabetes Researcher Spotlight: Richard Siller, PhD
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Thursday, February 24, 2022
The Affordable Insulin Now Act Includes a Monthly Out-Of-Pocket Patient Maximum of $35 for Insulin Prescriptions
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Wednesday, February 23, 2022
Care Team Spotlight: Nancy Morris - Nurse Practitioner
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Friday, February 11, 2022
The Diabetes Center of Excellence and Worcester Polytechnic Institute Awarded a Grant to Develop Type 1 Diabetes Research Tools
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Thursday, February 10, 2022
Type 2 Diabetes Researcher Spotlight: Emmanouela Tsagkaraki, MD, PhD
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Thursday, February 03, 2022
Identifying Genes and Signaling Pathways to Develop Thymus Cells to Explore the Root Cause of Type 1 Diabetes in the Maehr Lab
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Wednesday, February 16, 2022
The Latest Blood Glucose Management Tools and Products
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Friday, January 28, 2022
Care Team Spotlight: Jason Samlin, PsyD - Health Psychologist
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Monday, January 03, 2022
Gene Analysis Research Uncovered a Physiological Brake Protecting Thermogenesis in Fat Tissue
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Tuesday, January 18, 2022
Generous Donation from the Arthur M. and Martha R. Pappas Foundation Advances UMass Diabetes Research Capabilities
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Monday, December 20, 2021
Modeling and Studying the Autoimmune Processes of Human Type 1 Diabetes Using Human Cells and Tissue
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Tuesday, December 14, 2021
Diabetes Nurse Practitioner Nancy Sidhom Describes the Benefits of Continuous Glucose Monitors
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Thursday, December 09, 2021
Identifying Therapeutic Targets Using RNAi Technology to Treat Non-alcoholic Steatohepatitis (NASH) in the Czech Lab
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Wednesday, November 24, 2021
Partial Clinical Remission Reduces Lipid-Based Cardiovascular Risk in Adult Patients with Type 1 Diabetes
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Tuesday, November 09, 2021
Type 2 Diabetes Researcher Spotlight: Adilson Guilherme, PhD
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Thursday, October 28, 2021
The Wang Lab Sheds New Light on the Relationship Between Viral Infections and Type 1 Diabetes
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Friday, October 22, 2021
The Greiner Lab is Helping to Improve a Therapeutic Macroencapsulation Device to Advance the Development of Beta Cell Replacement Technology
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Wednesday, October 06, 2021
Type 1 Diabetes Researcher Spotlight: Sambra Redick, PhD
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Monday, September 27, 2021
Care Team Spotlight: Prateek Shukla, MD – Endocrinologist
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Thursday, September 16, 2021
Bioinformatician Mason Tarpley Named Cammett Scholar in Type 1 Diabetes Research
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Friday, September 10, 2021
Mello Scholar Awards Recognize Molecular Research, including Type 2 Diabetes Studies at UMass Chan Medical School
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Thursday, September 09, 2021
Type 2 Diabetes Research in the Guertin Lab Tracked and Discovered New Functions of Glucose in Brown Fat
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Wednesday, September 08, 2021
Researcher Spotlight: Carey Zammitti
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Wednesday, September 01, 2021
Investigating Leptin Regulation of the Human Diabetic Immune System in Nonhealing Diabetic Foot Ulcers
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Friday, August 20, 2021
Care Team Spotlight: Mark O’Connor, MD – Endocrinologist
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Tuesday, August 17, 2021
The COVID-19 Pandemic and Pediatric Type 1 Diabetes
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Friday, July 30, 2021
FDA Approves Interchangeable Biosimilar Insulin to Potentially Reduce Cost for People to Treat Diabetes
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Monday, July 19, 2021
Means, Motive, and Opportunity: Investigating the Role of Immune Cells in the Development of Type 1 Diabetes
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Friday, July 16, 2021
Care Team Spotlight: Asem Ali, MD - Endocrinologist
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Thursday, July 08, 2021
Researcher Spotlight: Pamela St. Louis
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Friday, July 02, 2021
Diabetes Screenings at UMass Memorial Health Clinic for People Experiencing Homelessness
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Thursday, July 29, 2021
Diabetes Virtual Camp for Future Scientists and Physicians Created by the Family of UMass Diabetes Researcher Jason Kim
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Thursday, June 17, 2021
Dr. John Mordes is Studying Genes to Predict Type 1 Diabetes Susceptibility in a Unique Rat Model of T1D
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Friday, May 21, 2021
UMass Diabetes Nurse Practitioner Sean Collins Appointed Commander of the Air Force Medical Readiness Agency
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Friday, April 30, 2021
Roger Davis Elected to The American Academy of Arts & Sciences
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Thursday, April 29, 2021
UMass DCOE Scientist Sally Kent Contributed to a Newly Published Study of Proinsulin
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Friday, April 16, 2021
UMass Diabetes Center of Excellence Researchers Recognized in Cell Metabolism's 100 Years of Insulin Issue
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Friday, March 19, 2021
Clinical Study Evaluates a Remote Glucose Monitoring Program to Help People With Poorly Controlled Type 2 Diabetes
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Wednesday, March 03, 2021
Researcher Spotlight: Sushobhana Bandyopadhyay, PhD
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Tuesday, February 23, 2021
Genetically Engineering & Testing Human Insulin-Producing Cells as a Potential Therapy or Cure for Type 1 Diabetes
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Friday, February 19, 2021
Dr. David Harlan Celebrates 100 Years Since the Initial Purification & Use of Insulin in Diabetes Therapy with "The Noble and Often Nobel Role of Insulin-Related Research"
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Tuesday, January 26, 2021
Tammy Nguyen Received a Vascular and Endovascular Surgery Society Award to Investigate Diabetic Wound Healing Problems
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Friday, January 15, 2021
Diabetes Virtual Camp for Future Scientists and Physicians Created by the Family of UMass Diabetes Researcher Jason Kim
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Thursday, January 14, 2021
UMass Diabetes Nurse Practitioner, Brig. Gen. Sean Collins Was Appointed to Board of Trustees for the Holyoke Soldiers’ Home
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Tuesday, January 05, 2021
Investigating a Potential Hormone Therapy for Type 2 Diabetes in the Davis Lab at UMass Medical School
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Monday, November 22, 2021
The Joseph Nozzolillo Memorial Foundation Surpassed $60,000 in Research Fundraising for the UMass Diabetes Center of Excellence
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Monday, November 30, 2020
Protein Commonly Screened For During Pregnancy is Linked to Gestational Diabetes at UMass Medical School
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Wednesday, November 18, 2020
The Messina Lab is Developing a Treatment for Previously Non-Healing Wounds in People with Diabetes
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Thursday, October 29, 2020
Re-engineering “Bad Fat” into “Good Fat” as a Therapeutic Approach to Type 2 Diabetes in the Czech & Corvera Labs
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Saturday, October 10, 2020
Studying Fat Cell Function in the Guertin Lab in an Effort to Develop & Test Therapies for Type 2 Diabetes
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Saturday, October 17, 2020
The Corvera Lab is Examining How Different Body Fat Plays a Role in Type 2 Diabetes
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Thursday, October 22, 2020
Care Team Spotlight: Victoria Andersen, Clinical Nutritionist & Diabetes Educator
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Thursday, October 08, 2020
Care Team Spotlight: Taylor Boudreau, Diabetes Nurse Practitioner
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Saturday, October 03, 2020
Mello Scholars Recognized for Molecular Research at UMass Medical School in Pursuit of the Advancement of Human Health
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Friday, September 25, 2020
Care Team Spotlight: Lindsey Gurry - Nurse Practitioner & Diabetes Educator
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Wednesday, September 23, 2020
Dr. Clifford Rosen Presented at UMass Endocrine Grand Rounds and Remembered Longtime Mentor and Friend Dr. Lewis E. Braverman
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Friday, September 11, 2020
Care Team Spotlight: Jessin Varghese, MS, FNP-BC
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Wednesday, August 26, 2020
Dr. Silvia Corvera Leads a New Clinical Trial to Study the Relationship Between Fat, Diabetes and Obesity
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Wednesday, August 19, 2020
The Kim Lab Participated in Newly Published Collaborative Type 2 Diabetes Research That Identified a Potential Oral Treatment
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Thursday, July 30, 2020
Research Project at UMass Medical School to Improve Prediabetes and Diabetes in Primary Health Care
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Friday, July 24, 2020
Modeling Type 1 Diabetes Using Human Stem Cells in the Brehm and Greiner Labs
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Wednesday, July 15, 2020
A Study by Dr. Benjamin Nwosu Shows Continuous Glucose Monitors Reduced Pubertal Hyperglycemia in Type 1 Diabetes
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Thursday, July 09, 2020
UMass DCOE Scientist Sally Kent Contributed to a Published Article About the Autoimmune Process of Type 1 Diabetes
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Wednesday, July 01, 2020
A Study by Dr. Amy Darukhanavala Compared Blood Sugar Control and Treatment Satisfaction Between Diabetes Camp vs. Home
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Wednesday, June 17, 2020
Physician-Scientist Jennifer Wang Uses Stem-Cell Derived Beta Cells to Study the Effects of Viral Infections on Type 1 Diabetes Development
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Wednesday, June 10, 2020
UMass Diabetes Center of Excellence Improving Digital Health Solutions with Simplified Data Sharing
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Monday, June 01, 2020
What You Need to Know About the Metformin Recall
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Tuesday, May 19, 2020
Telehealth May Become the New Normal in Diabetes Care
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Thursday, May 14, 2020
Dr. David Harlan Collaborated on a Newly Published Study Investigating Smaller Pancreases in People with Type 1 Diabetes
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Tuesday, May 05, 2020
Type 2 Diabetes Research in the Czech Lab Investigating Beige Fat to Potentially Increase Metabolism
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Friday, April 24, 2020
Continuous Glucose Monitors Now Permitted at UMass Memorial to Monitor Diabetes Patients and Protect Hospital Workers During the COVID-19 Pandemic
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Tuesday, April 14, 2020
Alan Derr Named Cammett Scholar in Type 1 Diabetes Research at UMass Medical School
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Thursday, April 02, 2020
New Data Published from the Guertin Lab About mTORC2 Signaling in Brown Adipocytes
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Tuesday, February 18, 2020
ID PLUS Care program developed to help at-risk type 2 diabetes patients within UMass Memorial receive the care they need
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Friday, February 14, 2020
Psychosocial screening of youth with type 1 diabetes at the UMass Memorial Diabetes Center of Excellence
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Friday, February 07, 2020
Glass Family Fellowship in Diabetes Research Established at the UMass Medical School Diabetes Center of Excellence
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Friday, February 07, 2020
Davis Lab Sheds Light on Complications From High Blood Glucose and Excess Body Fat Which Lead to Type 2 Diabetes
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Monday, February 03, 2020
mTORC2 signaling study published in Nature Communications
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Sunday, February 02, 2020
Metabolic Network connects UMass Medical School metabolism researchers
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Wednesday, January 29, 2020
Developing a Thymus in the Maehr Lab to Improve Type 1 Diabetes Research
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Tuesday, January 21, 2020
The Harlan and Greiner Labs Developed a New Method to Study Human Cells and Tissue That Improves Type 1 Diabetes Research
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Friday, January 17, 2020
Using RNA Interference to Study Behaviors and Function Cells Within Adipose Fat Tissue and the Effect on Blood Glucose Metabolism
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Tuesday, February 25, 2020
David Harlan Interviews Nobel Laureate Wally Gilbert About His Pioneering Work in DNA Sequencing That Led to the Creation of the First Genetically Engineered Human Insulin
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Wednesday, December 11, 2019
Sally Kent Named Fuller Foundation Term Chair in Diabetes
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Friday, November 22, 2019
Care Team Spotlight: Rachael Armenti, RN, CDCES
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Tuesday, November 26, 2019
Guertin Lab review on the metabolism of fat cells in type 2 diabetes published in Current Diabetes Reports
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Wednesday, October 16, 2019
Mapping your plan to control blood glucose with the help of diabetes education
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Monday, October 07, 2019
Importance of a flu shot for people living with diabetes
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Friday, September 27, 2019
Carl H. June, MD, pioneer of CAR T Cell Immunotherapy
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Thursday, September 26, 2019
The Messina Lab is Developing Blood Stem Cell Approaches to Impaired Diabetic Wound Healing
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Friday, September 20, 2019
New research in the Corvera lab discovered new fat cells with specialized functions in the metabolism of the human body
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Wednesday, September 18, 2019
Development of a peer mentor support measure for parents raising youth with type 1 diabetes and youth with T1D
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Thursday, September 05, 2019
Brehm and Greiner laboratories testing islet encapsulation device in collaboration with Lockheed Martin & JDRF Research
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Sunday, September 01, 2019
Care Team Spotlight: Fernanda Costa, RN
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Wednesday, August 28, 2019
2nd Annual Memorial Golf Tournament to Benefit UMass Diabetes Center of Excellence
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Saturday, August 24, 2019
Continuous Glucose Monitors and Children with Type 1 Diabetes
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Wednesday, August 21, 2019
Care Team Spotlight: Alicia Warnock, MD
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Thursday, July 25, 2019
Kristin MacGregor studied the impact of integrated behavioral healthcare in diabetes and the data shows measurable benefits
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Saturday, June 22, 2019
Dr. David Harlan Presents "Going Beyond Insulin in Type 1 Diabetes" at the Endocrine Society's Annual Fellows Conference
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Friday, June 14, 2019
UMass Diabetes Center of Excellence at the American Diabetes Association's 79th Scientific Sessions
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Wednesday, June 05, 2019
Grant Awarded to Improve Inpatient Diabetes Care at UMass Memorial Hospitals
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Monday, April 08, 2019
Laura Alonso honored with election into the American Society for Clinical Investigation
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Friday, March 29, 2019
Harlan and Kent Labs resolved a 30 year debate by locating beta cells in people with T1D which express important immune pathway gene products
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Wednesday, March 27, 2019
Care Team Spotlight: Nancy Sidhom - Diabetes Nurse Practitioner & Certified Diabetes Care and Education Specialist
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Friday, March 22, 2019
Alonso Lab Demonstrates the Accuracy of BrdU Labeling to Measure Beta Cell Replication
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Tuesday, March 19, 2019
Benjamin Nwosu Examines Cholesterol at Puberty in Type 1 Diabetes
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Friday, February 22, 2019
Care Team Spotlight: Nicole Sauvé, Certified Child Life Specialist
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Friday, February 01, 2019
Corvera Lab Continues to Create "Good Fat" as a Potential Therapy for Type 2 Diabetes
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Monday, February 04, 2019
Research in the Brehm and Davis Laboratories Uncovered New Memory T Cells Data
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Thursday, January 10, 2019
MD/PhD Candidate Rachel Stamateris Named Ruth L. Kirschstein Fellow
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Tuesday, December 18, 2018
Research in the Harlan lab discovered a rare genetic defect that affects human beta cell function
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Thursday, December 06, 2018
New beta cell biomarker discovered in research involving the Greiner Lab: What does it mean for future diabetes research?
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Tuesday, November 13, 2018
New data about the "humanized" type 1 diabetes mouse models developed by collaborations in Greiner and Brehm labs
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Friday, November 02, 2018
UMass Diabetes Center of Excellence Receives a $10.5K Gift From a Grateful Family
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Monday, October 29, 2018
Michael Czech and Silvia Corvera receive $2.5 million grant to advance potential therapy for type 2 diabetes
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Wednesday, October 24, 2018
Care Team Spotlight: Elizabeth Tinios, DNP, FNP-C, CDCES
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Tuesday, August 07, 2018
Unexpected cell population slows down fat cells
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Tuesday, August 28, 2018
Jennifer Wang Receives Funding Grant to Continue Studying How Viruses Trigger Type 1 Diabetes
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Thursday, July 12, 2018
Why Language is Important in Diabetes Management
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Monday, July 09, 2018
Diabetes Education Offers Many Benefits
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Wednesday, June 20, 2018
The Maehr Lab's Thymus Development Study Featured as the Cover Story in Immunity
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Wednesday, June 13, 2018
Care Team Spotlight: Christine Hoogasian - Nurse Practitioner
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Friday, May 18, 2018
New study of youth with type 1 diabetes connects ‘honeymoon period’ with lower LDL cholesterol
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Wednesday, May 09, 2018
Behavioral Health Integration in U.S. Diabetes Care: How Close Are We to ADA Recommendations?
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Thursday, May 03, 2018
Roger Davis Elected into the National Academy of Sciences
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Monday, May 07, 2018
The New York Times Asked Dr. David Harlan About Eating a Low-Carbohydrate & High Protein Diet with Type 1 Diabetes
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Wednesday, March 14, 2018
Dr. David Harlan and others provide a framework for developing a successful Diabetes Center of Excellence
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Monday, March 12, 2018
Alpha cell function and gene expression are compromised in type 1 diabetes according to Dr. Harlan, Dr. Greiner and a consortium of scientists
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Monday, April 30, 2018
Boston Ithaca Islet Club Annual Meeting held at UMass Medical
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Wednesday, March 07, 2018
Nancy Morris receives Excellence in Nursing Education Award from American Nursing Association Massachusetts
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Wednesday, February 28, 2018
Sally Kent receives Pioneer Award from the Network for Pancreatic Organ Donors with Diabetes (nPod)
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Wednesday, February 03, 2016
The Corvera Lab Sheds Light on Beige Fat as a Potential Therapy for Type 2 Diabetes
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Sunday, November 13, 2016
UMass Diabetes Nurse Practitioner Sean Collins joins the United States Defense Health Agency with promotion to Brigadier General in the Air Force, Air National Guard
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Monday, October 31, 2016
Scientists in Kent and Harlan labs isolate immune cells from the islets of donors with type 1 diabetes
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Monday, September 26, 2016
UMass Medical School hosts American Diabetes Association Step Out Walk to Stop Diabetes
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Patient Wall of Honor
Nan Hilton was diagnosed with Type 2 diabetes at 23 years old. After years of medications and insulin, she made lifestyle modifications resulting in a 90 pound weight loss and she no longer takes any diabetes medications. During a difficult pregnancy, Nan developed severe diabetic retinopathy that required invasive surgery and painful injections. After giving birth she committed to make necessary changes. Meet Nan
Taylor Connor’s A1c reached 15% in 2011 and remained elevated until 2016. That’s when she made a personal commitment to her health and started 2022 with an all-time low A1c of 6.4%. Her inspiring story proves it’s never too late to take control of diabetes. Using an insulin pump for the first time and adopting a healthy eating lifestyle has changed her life. In addition to improved health, it also resulted in her attending nursing school and today she’s a UMass Memorial Health Nurse and plans to become a Diabetes Educator.
Meet Taylor
Andrew Nelson was diagnosed with insulin-dependent diabetes due to damage caused by pancreatitis. He was referred to the UMass Diabetes Center of Excellence taking multiple daily insulin injections and other oral medications. Today he is no longer taking any medications, including insulin! He credits his care team with helping him become educated about diabetes management which allowed him to make the necessary modifications to improve his health.
Meet Andrew