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Publications 2022

Agwati EO, Oduor CI, Ayieko C, Ong'echa JM, Moormann AM, Bailey JA. Profiling genome-wide recombination in Epstein Barr virus reveals type-specific patterns and associations with endemic-Burkitt lymphoma. Virol J. 2022;19(1):208. Epub 2022/12/10. doi: 10.1186/s12985-022-01942-8. PubMed PMID: 36482473; PMCID: PMC9733152.
https://www.ncbi.nlm.nih.gov/pubmed/36482473 

Ahuja P, Ng CF, Pang BPS, Chan WS, Tse MCL, Bi X, Kwan HR, Brobst D, Herlea-Pana O, Yang X, Du G, Saengnipanthkul S, Noh HL, Jiao B, Kim JK, Lee CW, Ye K, Chan CB. Muscle-generated BDNF (brain derived neurotrophic factor) maintains mitochondrial quality control in female mice. Autophagy. 2022;18(6):1367-84. Epub 2021/10/26. doi: 10.1080/15548627.2021.1985257. PubMed PMID: 34689722; PMCID: PMC9225428.
https://www.ncbi.nlm.nih.gov/pubmed/34689722  

Aryee KE, Burzenski LM, Yao LC, Keck JG, Greiner DL, Shultz LD, Brehm MA. Enhanced development of functional human NK cells in NOD-scid-IL2rg(null) mice expressing human IL15. FASEB J. 2022;36(9):e22476. Epub 2022/08/13. doi: 10.1096/fj.202200045R. PubMed PMID: 35959876; PMCID: PMC9383543.
https://www.ncbi.nlm.nih.gov/pubmed/35959876 

Baier AS, Peterson CL. Fluorescence approaches for biochemical analysis of ATP-dependent chromatin remodeling enzymes. Methods Enzymol. 2022;673:1-17. Epub 2022/08/15. doi: 10.1016/bs.mie.2022.02.024. PubMed PMID: 35965003.
https://www.ncbi.nlm.nih.gov/pubmed/35965003  

Blaxter M, Archibald JM, Childers AK, Coddington JA, Crandall KA, Di Palma F, Durbin R, Edwards SV, Graves JAM, Hackett KJ, Hall N, Jarvis ED, Johnson RN, Karlsson EK, Kress WJ, Kuraku S, Lawniczak MKN, Lindblad-Toh K, Lopez JV, Moran NA, Robinson GE, Ryder OA, Shapiro B, Soltis PS, Warnow T, Zhang G, Lewin HA. Why sequence all eukaryotes? Proc Natl Acad Sci U S A. 2022;119(4). Epub 2022/01/20. doi: 10.1073/pnas.2115636118. PubMed PMID: 35042801; PMCID: PMC8795522.
https://www.ncbi.nlm.nih.gov/pubmed/35042801 

Boehm U, Nelson G, Brown CM, Bagley S, Bajcsy P, Bischof J, Dauphin A, Dobbie IM, Eriksson JE, Faklaris O, Fernandez-Rodriguez J, Ferrand A, Gelman L, Gheisari A, Hartmann H, Kukat C, Laude A, Mitkovski M, Munck S, North AJ, Rasse TM, Resch-Genger U, Schuetz LC, Seitz A, Strambio-De-Castillia C, Swedlow JR, Nitschke R. Author Correction: QUAREP-LiMi: a community endeavor to advance quality assessment and reproducibility in light microscopy. Nat Methods. 2022;19(2):256. Epub 2022/01/05. doi: 10.1038/s41592-021-01387-x. PubMed PMID: 34980905.
https://www.ncbi.nlm.nih.gov/pubmed/34980905  

Bouzid T, Esfahani AM, Safa BT, Kim E, Saraswathi V, Kim JK, Yang R, Lim JY. Rho/ROCK mechanosensor in adipocyte stiffness and traction force generation. Biochem Biophys Res Commun. 2022;606:42-8. Epub 2022/03/28. doi: 10.1016/j.bbrc.2022.03.078. PubMed PMID: 35339750; PMCID: PMC9035097.
https://www.ncbi.nlm.nih.gov/pubmed/35339750 

Bradley ES, Zeamer AL, Bucci V, Cincotta L, Salive MC, Dutta P, Mutaawe S, Anya O, Tocci C, Moormann A, Ward DV, McCormick BA, Haran JP. Oropharyngeal microbiome profiled at admission is predictive of the need for respiratory support among COVID-19 patients. Front Microbiol. 2022;13:1009440. Epub 2022/10/18. doi: 10.3389/fmicb.2022.1009440. PubMed PMID: 36246273; PMCID: PMC9561819.
https://www.ncbi.nlm.nih.gov/pubmed/36246273  

Braschi B, Omran H, Witman GB, Pazour GJ, Pfister KK, Bruford EA, King SM. Consensus nomenclature for dyneins and associated assembly factors. J Cell Biol. 2022;221(2). Epub 2022/01/11. doi: 10.1083/jcb.202109014. PubMed PMID: 35006274; PMCID: PMC8754002.
https://www.ncbi.nlm.nih.gov/pubmed/35006274 

Bryll AR, Peterson CL. Functional interaction between the RNA exosome and the sirtuin deacetylase Hst3 maintains transcriptional homeostasis. Genes Dev. 2022;36(1-2):17-22. Epub 2021/12/18. doi: 10.1101/gad.348923.121. PubMed PMID: 34916303; PMCID: PMC8763048. https://www.ncbi.nlm.nih.gov/pubmed/34916303 

Cable J, Fauci A, Dowling WE, Gunther S, Bente DA, Yadav PD, Madoff LC, Wang LF, Arora RK, Van Kerkhove M, Chu MC, Jaenisch T, Epstein JH, Frost SDW, Bausch DG, Hensley LE, Bergeron E, Sitaras I, Gunn MD, Geisbert TW, Munoz-Fontela C, Krammer F, de Wit E, Nordenfelt P, Saphire EO, Gilbert SC, Corbett KS, Branco LM, Baize S, van Doremalen N, Krieger MA, Clemens SAC, Hesselink R, Hartman D. Lessons from the pandemic: Responding to emerging zoonotic viral diseases-a Keystone Symposia report. Ann N Y Acad Sci. 2022;1518(1):209-25. Epub 2022/10/03. doi: 10.1111/nyas.14898. PubMed PMID: 36183296; PMCID: PMC9538336.
https://www.ncbi.nlm.nih.gov/pubmed/36183296 

Calejman CM, Doxsey WG, Fazakerley DJ, Guertin DA. Integrating adipocyte insulin signaling and metabolism in the multi-omics era. Trends Biochem Sci. 2022;47(6):531-46. Epub 2022/03/20. doi: 10.1016/j.tibs.2022.02.009. PubMed PMID: 35304047; PMCID: PMC9109456. https://www.ncbi.nlm.nih.gov/pubmed/35304047 

Chang CW, Parsi KM, Somasundaran M, Vanderleeden E, Liu P, Cruz J, Cousineau A, Finberg RW, Kurt-Jones EA. A Newly Engineered A549 Cell Line Expressing ACE2 and TMPRSS2 Is Highly Permissive to SARS-CoV-2, Including the Delta and Omicron Variants. Viruses. 2022;14(7). Epub 2022/07/28. doi: 10.3390/v14071369. PubMed PMID: 35891350; PMCID: PMC9318744.
https://www.ncbi.nlm.nih.gov/pubmed/35891350  

Chen Q, Huang L, Pan D, Hu K, Li R, Friedline RH, Kim JK, Zhu LJ, Guertin DA, Wang YX. A brown fat-enriched adipokine Adissp controls adipose thermogenesis and glucose homeostasis. Nat Commun. 2022;13(1):7633. Epub 2022/12/11. doi: 10.1038/s41467-022-35335-w. PubMed PMID: 36496438; PMCID: PMC9741603.
https://www.ncbi.nlm.nih.gov/pubmed/36496438  

Chen Z, Devi G, Arif A, Zamore PD, Sontheimer EJ, Watts JK. Tetrazine-Ligated CRISPR sgRNAs for Efficient Genome Editing. ACS Chem Biol. 2022;17(5):1045-50. Epub 2022/04/22. doi: 10.1021/acschembio.2c00116. PubMed PMID: 35446558; PMCID: PMC9127786. https://www.ncbi.nlm.nih.gov/pubmed/35446558 

Chicca J, Cazeault NR, Rus F, Abraham A, Garceau C, Li H, Atwa SM, Flanagan K, Soto ER, Morrison MS, Gazzola D, Hu Y, Liu DR, Nielsen MK, Urban JF, Jr., Ostroff GR, Aroian RV. Efficient and Scalable Process to Produce Novel and Highly Bioactive Purified Cytosolic Crystals from Bacillus thuringiensis. Microbiol Spectr. 2022;10(4):e0235622. Epub 2022/08/11. doi: 10.1128/spectrum.02356-22. PubMed PMID: 35946940; PMCID: PMC9430767.
https://www.ncbi.nlm.nih.gov/pubmed/35946940  

Conti MM, Ghizzoni JM, Gil-Bona A, Wang W, Costanzo M, Li R, Flynn MJ, Zhu LJ, Myers CL, Boone C, Andrews BJ, Benanti JA. Repression of essential cell cycle genes increases cellular fitness. PLoS Genet. 2022;18(8):e1010349. Epub 2022/08/30. doi: 10.1371/journal.pgen.1010349. PubMed PMID: 36037231; PMCID: PMC9462756.
https://www.ncbi.nlm.nih.gov/pubmed/36037231  

Corvera S. Perinatal fat progenitors shape adult metabolism. Nat Metab. 2022;4(8):963-4. Epub 2022/08/19. doi: 10.1038/s42255-022-00626-5. PubMed PMID: 35982291; PMCID: PMC9534327.
https://www.ncbi.nlm.nih.gov/pubmed/35982291  

Corvera S, Solivan-Rivera J, Yang Loureiro Z. Angiogenesis in adipose tissue and obesity. Angiogenesis. 2022;25(4):439-53. Epub 2022/07/21. doi: 10.1007/s10456-022-09848-3. PubMed PMID: 35857195; PMCID: PMC9519636.
https://www.ncbi.nlm.nih.gov/pubmed/35857195  

Damas J, Corbo M, Kim J, Turner-Maier J, Farre M, Larkin DM, Ryder OA, Steiner C, Houck ML, Hall S, Shiue L, Thomas S, Swale T, Daly M, Korlach J, Uliano-Silva M, Mazzoni CJ, Birren BW, Genereux DP, Johnson J, Lindblad-Toh K, Karlsson EK, Nweeia MT, Johnson RN, Zoonomia C, Lewin HA. Evolution of the ancestral mammalian karyotype and syntenic regions. Proc Natl Acad Sci U S A. 2022;119(40):e2209139119. Epub 2022/09/27. doi: 10.1073/pnas.2209139119. PubMed PMID: 36161960; PMCID: PMC9550189. https://www.ncbi.nlm.nih.gov/pubmed/36161960 

Darp R, Vittoria MA, Ganem NJ, Ceol CJ. Oncogenic BRAF induces whole-genome doubling through suppression of cytokinesis. Nat Commun. 2022;13(1):4109. Epub 2022/07/16. doi: 10.1038/s41467-022-31899-9. PubMed PMID: 35840569; PMCID: PMC9287415. https://www.ncbi.nlm.nih.gov/pubmed/35840569 

Diaz-Salinas MA, Li Q, Ejemel M, Yurkovetskiy L, Luban J, Shen K, Wang Y, Munro JB. Conformational dynamics and allosteric modulation of the SARS-CoV-2 spike. Elife. 2022;11. Epub 2022/03/25. doi: 10.7554/eLife.75433. PubMed PMID: 35323111; PMCID: PMC8963877. https://www.ncbi.nlm.nih.gov/pubmed/35323111  

Donnard E, Shu H, Garber M. Single cell transcriptomics reveals dysregulated cellular and molecular networks in a fragile X syndrome model. PLoS Genet. 2022;18(6):e1010221. Epub 2022/06/09. doi: 10.1371/journal.pgen.1010221. PubMed PMID: 35675353; PMCID: PMC9212148. https://www.ncbi.nlm.nih.gov/pubmed/35675353 

Doxsey DD, Shen K. Purification and biochemical characterization of the Rag GTPase heterodimer. Methods Enzymol. 2022;675:131-58. Epub 2022/10/12. doi: 10.1016/bs.mie.2022.07.007. PubMed PMID: 36220268.
https://www.ncbi.nlm.nih.gov/pubmed/36220268  

Doxsey DD, Veinotte K, Shen K. A New Crosslinking Assay to Study Guanine Nucleotide Binding in the Gtr Heterodimer of S. cerevisiae. Small GTPases. 2022;13(1):327-34. Epub 2022/11/04. doi: 10.1080/21541248.2022.2141019. PubMed PMID: 36328771; PMCID: PMC9639563.
https://www.ncbi.nlm.nih.gov/pubmed/36328771 

Duan Y, Veksler-Lublinsky I, Ambros V. Critical contribution of 3' non-seed base pairing to the in vivo function of the evolutionarily conserved let-7a microRNA. Cell Rep. 2022;39(4):110745. Epub 2022/04/28. doi: 10.1016/j.celrep.2022.110745. PubMed PMID: 35476978; PMCID: PMC9161110.
https://www.ncbi.nlm.nih.gov/pubmed/35476978 

Egri SB, Ouch C, Chou HT, Yu Z, Song K, Xu C, Shen K. Cryo-EM structures of the human GATOR1-Rag-Ragulator complex reveal a spatial-constraint regulated GAP mechanism. Mol Cell. 2022;82(10):1836-49 e5. Epub 2022/03/27. doi: 10.1016/j.molcel.2022.03.002. PubMed PMID: 35338845; PMCID: PMC9133170.
https://www.ncbi.nlm.nih.gov/pubmed/35338845 

Expert Panels on T, Gastrointestinal I, Raptis CA, Goldstein A, Henry TS, Porter KK, Catenacci D, Kelly AM, Kuzniewski CT, Lai AR, Lee E, Long JM, Martin MD, Morris MF, Sandler KL, Sirajuddin A, Surasi DS, Wallace GW, Kamel IR, Donnelly EF. ACR Appropriateness Criteria(R) Staging and Follow-Up of Esophageal Cancer. J Am Coll Radiol. 2022;19(11S):S462-S72. Epub 2022/11/28. doi: 10.1016/j.jacr.2022.09.008. PubMed PMID: 36436970.
https://www.ncbi.nlm.nih.gov/pubmed/36436970 

Fan J, Moreno AT, Baier AS, Loparo JJ, Peterson CL. H2A.Z deposition by SWR1C involves multiple ATP-dependent steps. Nat Commun. 2022;13(1):7052. Epub 2022/11/18. doi: 10.1038/s41467-022-34861-x. PubMed PMID: 36396651; PMCID: PMC9672302.
https://www.ncbi.nlm.nih.gov/pubmed/36396651 

Frantz WT, Ceol CJ. Research Techniques Made Simple: Zebrafish Models for Human Dermatologic Disease. J Invest Dermatol. 2022;142(3 Pt A):499-506 e1. Epub 2022/02/22. doi: 10.1016/j.jid.2021.10.016. PubMed PMID: 35184798.
https://www.ncbi.nlm.nih.gov/pubmed/35184798  

Garg S, Kreutzfeld O, Chelebieva S, Tumwebaze PK, Byaruhanga O, Okitwi M, Orena S, Katairo T, Nsobya SL, Conrad MD, Aydemir O, Legac J, Gould AE, Bayles BR, Bailey JA, Duffey M, Lin G, Kirkman LA, Cooper RA, Rosenthal PJ. Susceptibilities of Ugandan Plasmodium falciparum Isolates to Proteasome Inhibitors. Antimicrob Agents Chemother. 2022;66(10):e0081722. Epub 2022/09/13. doi: 10.1128/aac.00817-22. PubMed PMID: 36094216; PMCID: PMC9578402.
https://www.ncbi.nlm.nih.gov/pubmed/36094216  

Goo BS, Mun DJ, Kim S, Nhung TTM, Lee SB, Woo Y, Kim SJ, Suh BK, Park SJ, Lee HE, Park K, Jang H, Rah JC, Yoon KJ, Baek ST, Park SY, Park SK. Schizophrenia-associated Mitotic Arrest Deficient-1 (MAD1) regulates the polarity of migrating neurons in the developing neocortex. Mol Psychiatry. 2023;28(2):856-70. Epub 2022/11/11. doi: 10.1038/s41380-022-01856-5. PubMed PMID: 36357673; PMCID: PMC9908555.
https://www.ncbi.nlm.nih.gov/pubmed/36357673  

Guilherme A, Rowland LA, Wang H, Czech MP. The adipocyte supersystem of insulin and cAMP signaling. Trends Cell Biol. 2022. Epub 2022/08/22. doi: 10.1016/j.tcb.2022.07.009. PubMed PMID: 35989245.
https://www.ncbi.nlm.nih.gov/pubmed/35989245  

Guo D, Daman K, Chen JJ, Shi MJ, Yan J, Matijasevic Z, Rickard AM, Bennett MH, Kiselyov A, Zhou H, Bang AG, Wagner KR, Maehr R, King OD, Hayward LJ, Emerson CP, Jr. iMyoblasts for ex vivo and in vivo investigations of human myogenesis and disease modeling. Elife. 2022;11. Epub 2022/01/26. doi: 10.7554/eLife.70341. PubMed PMID: 35076017; PMCID: PMC8789283.
https://www.ncbi.nlm.nih.gov/pubmed/35076017  

Gutierrez JI, Brittingham GP, Karadeniz Y, Tran KD, Dutta A, Holehouse AS, Peterson CL, Holt LJ. SWI/SNF senses carbon starvation with a pH-sensitive low-complexity sequence. Elife. 2022;11. Epub 2022/02/08. doi: 10.7554/eLife.70344. PubMed PMID: 35129437; PMCID: PMC8890752.
https://www.ncbi.nlm.nih.gov/pubmed/35129437 

Hammer M, Huisman M, Rigano A, Boehm U, Chambers JJ, Gaudreault N, North AJ, Pimentel JA, Sudar D, Bajcsy P, Brown CM, Corbett AD, Faklaris O, Lacoste J, Laude A, Nelson G, Nitschke R, Farzam F, Smith CS, Grunwald D, Strambio-De-Castillia C. Author Correction: Towards community-driven metadata standards for light microscopy: tiered specifications extending the OME model. Nat Methods. 2022;19(2):255. Epub 2022/01/05. doi: 10.1038/s41592-021-01386-y. PubMed PMID: 34980906.
https://www.ncbi.nlm.nih.gov/pubmed/34980906 

Hamza ZK, Hathout AS, Ostroff G, Soto E, Sabry BA, El-Hashash MA, Hassan NS, Aly SE. Assessment of the protective effect of yeast cell wall beta-glucan encapsulating humic acid nanoparticles as an aflatoxin B(1) adsorbent in vivo. J Biochem Mol Toxicol. 2022;36(1):e22941. Epub 2021/11/03. doi: 10.1002/jbt.22941. PubMed PMID: 34726330.
https://www.ncbi.nlm.nih.gov/pubmed/34726330 

Hansen JN, Kaiser F, Leyendecker P, Stuven B, Krause JH, Derakhshandeh F, Irfan J, Sroka TJ, Preval KM, Desai PB, Kraut M, Theis H, Drews AD, De-Domenico E, Handler K, Pazour GJ, Henderson DJP, Mick DU, Wachten D. A cAMP signalosome in primary cilia drives gene expression and kidney cyst formation. EMBO Rep. 2022;23(8):e54315. Epub 2022/06/14. doi: 10.15252/embr.202154315. PubMed PMID: 35695071; PMCID: PMC9346484.
https://www.ncbi.nlm.nih.gov/pubmed/35695071 

Hester MM, Oliveira LVN, Wang R, Mou Z, Lourenco D, Ostroff GR, Specht CA, Levitz SM. Cross-reactivity between vaccine antigens from the chitin deacetylase protein family improves survival in a mouse model of cryptococcosis. Front Immunol. 2022;13:1015586. Epub 2022/10/18. doi: 10.3389/fimmu.2022.1015586. PubMed PMID: 36248898; PMCID: PMC9554598.
https://www.ncbi.nlm.nih.gov/pubmed/36248898  

Higgins DP, Weisman CM, Lui DS, D'Agostino FA, Walker AK. Defining characteristics and conservation of poorly annotated genes in Caenorhabditis elegans using WormCat 2.0. Genetics. 2022;221(4). Epub 2022/05/20. doi: 10.1093/genetics/iyac085. PubMed PMID: 35587742; PMCID: PMC9339291.
https://www.ncbi.nlm.nih.gov/pubmed/35587742  

Hu K, Liu H, Lawson ND, Zhu LJ. scATACpipe: A nextflow pipeline for comprehensive and reproducible analyses of single cell ATAC-seq data. Front Cell Dev Biol. 2022;10:981859. Epub 2022/10/15. doi: 10.3389/fcell.2022.981859. PubMed PMID: 36238687; PMCID: PMC9551270.
https://www.ncbi.nlm.nih.gov/pubmed/36238687  

Huang L, Liu P, Yang Q, Wang YX. The KRAB Domain-Containing Protein ZFP961 Represses Adipose Thermogenesis and Energy Expenditure through Interaction with PPARalpha. Adv Sci (Weinh). 2022;9(2):e2102949. Epub 2021/11/09. doi: 10.1002/advs.202102949. PubMed PMID: 34747141; PMCID: PMC8805557.
https://www.ncbi.nlm.nih.gov/pubmed/34747141 

Im DS, Joselin A, Svoboda D, Takano T, Rousseaux MWC, Callaghan S, Slack RS, Hisanaga SI, Davis RJ, Park DS, Qu D. Cdk5-mediated JIP1 phosphorylation regulates axonal outgrowth through Notch1 inhibition. BMC Biol. 2022;20(1):115. Epub 2022/05/18. doi: 10.1186/s12915-022-01312-4. PubMed PMID: 35581583; PMCID: PMC9115922.
https://www.ncbi.nlm.nih.gov/pubmed/35581583  

Ivshina MP, van 't Spijker HM, Jung S, Ponny SR, Schafer DP, Richter JD. CPEB1 regulates the inflammatory immune response, phagocytosis, and alternative polyadenylation in microglia. Glia. 2022;70(10):1850-63. Epub 2022/06/01. doi: 10.1002/glia.24222. PubMed PMID: 35635122; PMCID: PMC9378487.
https://www.ncbi.nlm.nih.gov/pubmed/35635122  

Iyer S, Mir A, Vega-Badillo J, Roscoe BP, Ibraheim R, Zhu LJ, Lee J, Liu P, Luk K, Mintzer E, Guo D, Soares de Brito J, Emerson CP, Jr., Zamore PD, Sontheimer EJ, Wolfe SA. Efficient Homology-Directed Repair with Circular Single-Stranded DNA Donors. CRISPR J. 2022;5(5):685-701. Epub 2022/09/08. doi: 10.1089/crispr.2022.0058. PubMed PMID: 36070530; PMCID: PMC9595650.
https://www.ncbi.nlm.nih.gov/pubmed/36070530 

Jiang T, Zhang XO, Weng Z, Xue W. Deletion and replacement of long genomic sequences using prime editing. Nat Biotechnol. 2022;40(2):227-34. Epub 2021/10/16. doi: 10.1038/s41587-021-01026-y. PubMed PMID: 34650270; PMCID: PMC8847310.
https://www.ncbi.nlm.nih.gov/pubmed/34650270  

Ju S, Chen H, Wang S, Lin J, Ma Y, Aroian RV, Peng D, Sun M. C. elegans monitor energy status via the AMPK pathway to trigger innate immune responses against bacterial pathogens. Commun Biol. 2022;5(1):643. Epub 2022/07/01. doi: 10.1038/s42003-022-03589-1. PubMed PMID: 35773333; PMCID: PMC9246835.
https://www.ncbi.nlm.nih.gov/pubmed/35773333  

Jung SM, Le J, Doxsey WG, Haley JA, Park G, Guertin DA, Jang C. Stable Isotope Tracing and Metabolomics to Study In Vivo Brown Adipose Tissue Metabolic Fluxes. Methods Mol Biol. 2022;2448:119-30. Epub 2022/02/16. doi: 10.1007/978-1-0716-2087-8_8. PubMed PMID: 35167094; PMCID: PMC9924221.
https://www.ncbi.nlm.nih.gov/pubmed/35167094 

Khosravi-Maharlooei M, Madley R, Borsotti C, Ferreira LMR, Sharp RC, Brehm MA, Greiner DL, Parent AV, Anderson MS, Sykes M, Creusot RJ. Modeling human T1D-associated autoimmune processes. Mol Metab. 2022;56:101417. Epub 2021/12/14. doi: 10.1016/j.molmet.2021.101417. PubMed PMID: 34902607; PMCID: PMC8739876.  
https://www.ncbi.nlm.nih.gov/pubmed/34902607 

Lee PJ, Kennedy Z, Wang Y, Lu Y, Cefaliello C, Uyan O, Song CQ, Godinho BMC, Xu Z, Rusckowski M, Xue W, Brown RH, Jr. Imaging Net Retrograde Axonal Transport In Vivo: A Physiological Biomarker. Ann Neurol. 2022;91(5):716-29. Epub 2022/02/19. doi: 10.1002/ana.26329. PubMed PMID: 35178738; PMCID: PMC9313858.
https://www.ncbi.nlm.nih.gov/pubmed/35178738  

Lemieux JE, Luban J. Consulting the Oracle of SARS-CoV-2 Infection. J Infect Dis. 2022;225(7):1115-7. Epub 2021/12/24. doi: 10.1093/infdis/jiab623. PubMed PMID: 34940876; PMCID: PMC8807189.
https://www.ncbi.nlm.nih.gov/pubmed/34940876  

Lewin HA, Richards S, Lieberman Aiden E, Allende ML, Archibald JM, Balint M, Barker KB, Baumgartner B, Belov K, Bertorelle G, Blaxter ML, Cai J, Caperello ND, Carlson K, Castilla-Rubio JC, Chaw SM, Chen L, Childers AK, Coddington JA, Conde DA, Corominas M, Crandall KA, Crawford AJ, DiPalma F, Durbin R, Ebenezer TE, Edwards SV, Fedrigo O, Flicek P, Formenti G, Gibbs RA, Gilbert MTP, Goldstein MM, Graves JM, Greely HT, Grigoriev IV, Hackett KJ, Hall N, Haussler D, Helgen KM, Hogg CJ, Isobe S, Jakobsen KS, Janke A, Jarvis ED, Johnson WE, Jones SJM, Karlsson EK, Kersey PJ, Kim JH, Kress WJ, Kuraku S, Lawniczak MKN, Leebens-Mack JH, Li X, Lindblad-Toh K, Liu X, Lopez JV, Marques-Bonet T, Mazard S, Mazet JAK, Mazzoni CJ, Myers EW, O'Neill RJ, Paez S, Park H, Robinson GE, Roquet C, Ryder OA, Sabir JSM, Shaffer HB, Shank TM, Sherkow JS, Soltis PS, Tang B, Tedersoo L, Uliano-Silva M, Wang K, Wei X, Wetzer R, Wilson JL, Xu X, Yang H, Yoder AD, Zhang G. The Earth BioGenome Project 2020: Starting the clock. Proc Natl Acad Sci U S A. 2022;119(4). Epub 2022/01/20. doi: 10.1073/pnas.2115635118. PubMed PMID: 35042800; PMCID: PMC8795548.
https://www.ncbi.nlm.nih.gov/pubmed/35042800  

Liang SQ, Liu P, Smith JL, Mintzer E, Maitland S, Dong X, Yang Q, Lee J, Haynes CM, Zhu LJ, Watts JK, Sontheimer EJ, Wolfe SA, Xue W. Genome-wide detection of CRISPR editing in vivo using GUIDE-tag. Nat Commun. 2022;13(1):437. Epub 2022/01/23. doi: 10.1038/s41467-022-28135-9. PubMed PMID: 35064134; PMCID: PMC8782884.
https://www.ncbi.nlm.nih.gov/pubmed/35064134  

Lilly CM, Wang Z, Dunlap D, Kaye J, Gohtard S, Teebagy S, Hafer N, Rogers EJ, Buchholz B, McManus D. 2021 Patient Preferences for Point of Care Testing Survey: More Acceptance and Less Concern. J Appl Lab Med. 2022;7(6):1302-10. Epub 2022/09/13. doi: 10.1093/jalm/jfac070. PubMed PMID: 36093730.
https://www.ncbi.nlm.nih.gov/pubmed/36093730  

Liu PW, Martin GL, Lin W, Huang W, Pande S, Aronovitz MJ, Davis RJ, Blanton RM. Mixed lineage kinase 3 requires a functional CRIB domain for regulation of blood pressure, cardiac hypertrophy, and left ventricular function. Am J Physiol Heart Circ Physiol. 2022;323(3):H513-H22. Epub 2022/07/23. doi: 10.1152/ajpheart.00660.2021. PubMed PMID: 35867711; PMCID: PMC9448288.
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Luciano AK, Korobkina ED, Lyons SP, Haley JA, Fluharty SM, Jung SM, Kettenbach AN, Guertin DA. Proximity labeling of endogenous RICTOR identifies mTOR complex 2 regulation by ADP ribosylation factor ARF1. J Biol Chem. 2022;298(10):102379. Epub 2022/08/17. doi: 10.1016/j.jbc.2022.102379. PubMed PMID: 35973513; PMCID: PMC9513271.
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Lv B, Zhang XO, Pazour GJ. Arih2 regulates Hedgehog signaling through smoothened ubiquitylation and ER-associated degradation. J Cell Sci. 2022;135(16). Epub 2022/07/29. doi: 10.1242/jcs.260299. PubMed PMID: 35899529; PMCID: PMC9481925.
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Ly S, Didiot MC, Ferguson CM, Coles AH, Miller R, Chase K, Echeverria D, Wang F, Sadri-Vakili G, Aronin N, Khvorova A. Mutant huntingtin messenger RNA forms neuronal nuclear clusters in rodent and human brains. Brain Commun. 2022;4(6):fcac248. Epub 2022/12/03. doi: 10.1093/braincomms/fcac248. PubMed PMID: 36458209; PMCID: PMC9707646.
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Ma KC, Hale JE, Grad YH, Alter G, Luzuriaga K, Eaton RB, Fischinger S, Kaur D, Brody R, Siddiqui SM, Leach D, Brown CM, Klevens RM, Madoff L, Comeau AM. Trends in Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Seroprevalence in Massachusetts Estimated from Newborn Screening Specimens. Clin Infect Dis. 2022;75(1):e105-e13. Epub 2022/02/26. doi: 10.1093/cid/ciac158. PubMed PMID: 35213690; PMCID: PMC8903451.
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Magaletta ME, Lobo M, Kernfeld EM, Aliee H, Huey JD, Parsons TJ, Theis FJ, Maehr R. Integration of single-cell transcriptomes and chromatin landscapes reveals regulatory programs driving pharyngeal organ development. Nat Commun. 2022;13(1):457. Epub 2022/01/26. doi: 10.1038/s41467-022-28067-4. PubMed PMID: 35075189; PMCID: PMC8786836 Dermagnostix GmbH and Cellarity. All other authors declare no competing interests.
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Morrill K, Hekman J, Li X, McClure J, Logan B, Goodman L, Gao M, Dong Y, Alonso M, Carmichael E, Snyder-Mackler N, Alonso J, Noh HJ, Johnson J, Koltookian M, Lieu C, Megquier K, Swofford R, Turner-Maier J, White ME, Weng Z, Colubri A, Genereux DP, Lord KA, Karlsson EK. Ancestry-inclusive dog genomics challenges popular breed stereotypes. Science. 2022;376(6592):eabk0639. Epub 2022/04/29. doi: 10.1126/science.abk0639. PubMed PMID: 35482869; PMCID: PMC9675396.
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Munch J, Engesser M, Schonauer R, Hamm JA, Hartig C, Hantmann E, Akay G, Pehlivan D, Mitani T, Coban Akdemir Z, Tuysuz B, Shirakawa T, Dateki S, Claus LR, van Eerde AM, Genomics England Research C, Smol T, Devisme L, Franquet H, Attie-Bitach T, Wagner T, Bergmann C, Hohn AK, Shril S, Pollack A, Wenger T, Scott AA, Paolucci S, Buchan J, Gabriel GC, Posey JE, Lupski JR, Petit F, McCarthy AA, Pazour GJ, Lo CW, Popp B, Halbritter J. Biallelic pathogenic variants in roundabout guidance receptor 1 associate with syndromic congenital anomalies of the kidney and urinary tract. Kidney Int. 2022;101(5):1039-53. Epub 2022/03/02. doi: 10.1016/j.kint.2022.01.028. PubMed PMID: 35227688.
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Obermeyer F, Jankowiak M, Barkas N, Schaffner SF, Pyle JD, Yurkovetskiy L, Bosso M, Park DJ, Babadi M, MacInnis BL, Luban J, Sabeti PC, Lemieux JE. Analysis of 6.4 million SARS-CoV-2 genomes identifies mutations associated with fitness. Science. 2022;376(6599):1327-32. Epub 2022/05/25. doi: 10.1126/science.abm1208. PubMed PMID: 35608456; PMCID: PMC9161372.
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Obermeyer F, Jankowiak M, Barkas N, Schaffner SF, Pyle JD, Yurkovetskiy L, Bosso M, Park DJ, Babadi M, MacInnis BL, Luban J, Sabeti PC, Lemieux JE. Analysis of 6.4 million SARS-CoV-2 genomes identifies mutations associated with fitness. medRxiv. 2022. Epub 2022/02/24. doi: 10.1101/2021.09.07.21263228. PubMed PMID: 35194619; PMCID: PMC8863165.
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Pan X, Yue Y, Boftsi M, Wasala LP, Tran NT, Zhang K, Pintel DJ, Tai PWL, Duan D. Rational engineering of a functional CpG-free ITR for AAV gene therapy. Gene Ther. 2022;29(6):333-45. Epub 2021/10/07. doi: 10.1038/s41434-021-00296-0. PubMed PMID: 34611321; PMCID: PMC8983793.
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Petros BA, Paull JS, Tomkins-Tinch CH, Loftness BC, DeRuff KC, Nair P, Gionet GL, Benz A, Brock-Fisher T, Hughes M, Yurkovetskiy L, Mulaudzi S, Leenerman E, Nyalile T, Moreno GK, Specht I, Sani K, Adams G, Babet SV, Baron E, Blank JT, Boehm C, Botti-Lodovico Y, Brown J, Buisker AR, Burcham T, Chylek L, Cronan P, Dauphin A, Desreumaux V, Doss M, Flynn B, Gladden-Young A, Glennon O, Harmon HD, Hook TV, Kary A, King C, Loreth C, Marrs L, McQuade KJ, Milton TT, Mulford JM, Oba K, Pearlman L, Schifferli M, Schmidt MJ, Tandus GM, Tyler A, Vodzak ME, Krohn Bevill K, Colubri A, MacInnis BL, Ozsoy AZ, Parrie E, Sholtes K, Siddle KJ, Fry B, Luban J, Park DJ, Marshall J, Bronson A, Schaffner SF, Sabeti PC. Multimodal surveillance of SARS-CoV-2 at a university enables development of a robust outbreak response framework. Med (N Y). 2022;3(12):883-900 e13. Epub 2022/10/06. doi: 10.1016/j.medj.2022.09.003. PubMed PMID: 36198312; PMCID: PMC9482833.
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Rigano A, Ehmsen S, Ozturk SU, Ryan J, Balashov A, Hammer M, Kirli K, Boehm U, Brown CM, Bellve K, Chambers JJ, Cosolo A, Coleman RA, Faklaris O, Fogarty KE, Guilbert T, Hamacher AB, Itano MS, Keeley DP, Kunis S, Lacoste J, Laude A, Ma WY, Marcello M, Montero-Llopis P, Nelson G, Nitschke R, Pimentel JA, Weidtkamp-Peters S, Park PJ, Alver BH, Grunwald D, Strambio-De-Castillia C. Author Correction: Micro-Meta App: an interactive tool for collecting microscopy metadata based on community specifications. Nat Methods. 2022;19(2):256. Epub 2021/12/26. doi: 10.1038/s41592-021-01388-w. PubMed PMID: 34952955; PMCID: PMC8828465.
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Ruggiero A, Pascucci GR, Cotugno N, Dominguez-Rodriguez S, Rinaldi S, Tagarro A, Rojo P, Foster C, Bamford A, De Rossi A, Nastouli E, Klein N, Morrocchi E, Fatou B, Smolen KK, Ozonoff A, Di Pastena M, Luzuriaga K, Steen H, Giaquinto C, Goulder P, Rossi P, Levy O, Pahwa S, Palma P, Consortium E. Determinants of B-Cell Compartment Hyperactivation in European Adolescents Living With Perinatally Acquired HIV-1 After Over 10 Years of Suppressive Therapy. Front Immunol. 2022;13:860418. Epub 2022/04/19. doi: 10.3389/fimmu.2022.860418. PubMed PMID: 35432380; PMCID: PMC9009387.
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Schwartz SM, Urfer SR, White M, Megquier K, Shrager S, Dog Aging Project C, Ruple A. Lifetime prevalence of malignant and benign tumours in companion dogs: Cross-sectional analysis of Dog Aging Project baseline survey. Vet Comp Oncol. 2022;20(4):797-804. Epub 2022/05/17. doi: 10.1111/vco.12839. PubMed PMID: 35574975.
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Shields A, Amcheslavsky A, Brown E, Lee TV, Nie Y, Tanji T, Ip YT, Bergmann A. Toll-9 interacts with Toll-1 to mediate a feedback loop during apoptosis-induced proliferation in Drosophila. Cell Rep. 2022;39(7):110817. Epub 2022/05/19. doi: 10.1016/j.celrep.2022.110817. PubMed PMID: 35584678; PMCID: PMC9211775. https://www.ncbi.nlm.nih.gov/pubmed/35584678 

Shin J, Paek KY, Chikhaoui L, Jung S, Ponny S, Suzuki Y, Padmanabhan K, Richter JD. Oppositional poly(A) tail length regulation by FMRP and CPEB1. RNA. 2022;28(5):756-65. Epub 2022/02/27. doi: 10.1261/rna.079050.121. PubMed PMID: 35217597; PMCID: PMC9014880.
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Shin M, Chan IL, Cao Y, Gruntman AM, Lee J, Sousa J, Rodriguez TC, Echeverria D, Devi G, Debacker AJ, Moazami MP, Krishnamurthy PM, Rembetsy-Brown JM, Kelly K, Yukselen O, Donnard E, Parsons TJ, Khvorova A, Sontheimer EJ, Maehr R, Garber M, Watts JK. Intratracheally administered LNA gapmer antisense oligonucleotides induce robust gene silencing in mouse lung fibroblasts. Nucleic Acids Res. 2022;50(15):8418-30. Epub 2022/08/04. doi: 10.1093/nar/gkac630. PubMed PMID: 35920332; PMCID: PMC9410908.
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Shinoda K, Choe A, Hirahara K, Kiuchi M, Kokubo K, Ichikawa T, Hoki JS, Suzuki AS, Bose N, Appleton JA, Aroian RV, Schroeder FC, Sternberg PW, Nakayama T. Nematode ascarosides attenuate mammalian type 2 inflammatory responses. Proc Natl Acad Sci U S A. 2022;119(9). Epub 2022/02/26. doi: 10.1073/pnas.2108686119. PubMed PMID: 35210367; PMCID: PMC8892368.
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Silverstein NJ, Wang Y, Manickas-Hill Z, Carbone C, Dauphin A, Boribong BP, Loiselle M, Davis J, Leonard MM, Kuri-Cervantes L, Collection MC-, Processing T, Meyer NJ, Betts MR, Li JZ, Walker BD, Yu XG, Yonker LM, Luban J. Innate lymphoid cells and COVID-19 severity in SARS-CoV-2 infection. Elife. 2022;11. Epub 2022/03/12. doi: 10.7554/eLife.74681. PubMed PMID: 35275061; PMCID: PMC9038195.
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Sitaram A, Yin Y, Zamaitis T, Zhang B, Aroian RV. A Caenorhabditis elegans nck-1 and filamentous actin-regulating protein pathway mediates a key cellular defense against bacterial pore-forming proteins. PLoS Pathog. 2022;18(11):e1010656. Epub 2022/11/15. doi: 10.1371/journal.ppat.1010656. PubMed PMID: 36374839; PMCID: PMC9704757.
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Skovso S, Panzhinskiy E, Kolic J, Cen HH, Dionne DA, Dai XQ, Sharma RB, Elghazi L, Ellis CE, Faulkner K, Marcil SAM, Overby P, Noursadeghi N, Hutchinson D, Hu X, Li H, Modi H, Wildi JS, Botezelli JD, Noh HL, Suk S, Gablaski B, Bautista A, Kim R, Cras-Meneur C, Flibotte S, Sinha S, Luciani DS, Nislow C, Rideout EJ, Cytrynbaum EN, Kim JK, Bernal-Mizrachi E, Alonso LC, MacDonald PE, Johnson JD. Beta-cell specific Insr deletion promotes insulin hypersecretion and improves glucose tolerance prior to global insulin resistance. Nat Commun. 2022;13(1):735. Epub 2022/02/10. doi: 10.1038/s41467-022-28039-8. PubMed PMID: 35136059; PMCID: PMC8826929.
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Smith AO, Jonassen JA, Preval KM, Davis RJ, Pazour GJ. c-JUN n-Terminal Kinase (JNK) Signaling in Autosomal Dominant Polycystic Kidney Disease. J Cell Signal. 2022;3(1):62-78. Epub 2022/03/08. doi: 10.33696/Signaling.3.068. PubMed PMID: 35253003; PMCID: PMC8896658.
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Solivan-Rivera J, Yang Loureiro Z, DeSouza T, Desai A, Pallat S, Yang Q, Rojas-Rodriguez R, Ziegler R, Skritakis P, Joyce S, Zhong D, Nguyen T, Corvera S. A neurogenic signature involving monoamine Oxidase-A controls human thermogenic adipose tissue development. Elife. 2022;11. Epub 2022/09/16. doi: 10.7554/eLife.78945. PubMed PMID: 36107478; PMCID: PMC9519151.
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Soni A, Herbert C, Filippaios A, Broach J, Colubri A, Fahey N, Woods K, Nanavati J, Wright C, Orwig T, Gilliam K, Kheterpal V, Suvarna T, Nowak C, Schrader S, Lin H, O'Connor L, Pretz C, Ayturk D, Orvek E, Flahive J, Lazar P, Shi Q, Achenbach C, Murphy R, Robinson M, Gibson L, Stamegna P, Hafer N, Luzuriaga K, Barton B, Heetderks W, Manabe YC, McManus D. Comparison of Rapid Antigen Tests' Performance Between Delta and Omicron Variants of SARS-CoV-2 : A Secondary Analysis From a Serial Home Self-testing Study. Ann Intern Med. 2022;175(12):1685-92. Epub 2022/10/11. doi: 10.7326/M22-0760. PubMed PMID: 36215709; PMCID: PMC9578286 www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=M22-0760.
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Soto ER, Rus F, Ostroff GR. Yeast Particles Hyper-Loaded with Terpenes for Biocide Applications. Molecules. 2022;27(11). Epub 2022/06/11. doi: 10.3390/molecules27113580. PubMed PMID: 35684516; PMCID: PMC9182042.
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Spears ME, Lee N, Hwang S, Park SJ, Carlisle AE, Li R, Doshi MB, Armando AM, Gao J, Simin K, Zhu LJ, Greer PL, Quehenberger O, Torres EM, Kim D. De novo sphingolipid biosynthesis necessitates detoxification in cancer cells. Cell Rep. 2022;40(13):111415. Epub 2022/09/29. doi: 10.1016/j.celrep.2022.111415. PubMed PMID: 36170811; PMCID: PMC9552870.
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Specht CA, Homan EJ, Lee CK, Mou Z, Gomez CL, Hester MM, Abraham A, Rus F, Ostroff GR, Levitz SM. Protection of Mice against Experimental Cryptococcosis by Synthesized Peptides Delivered in Glucan Particles. mBio. 2022;13(1):e0336721. Epub 2022/01/29. doi: 10.1128/mbio.03367-21. PubMed PMID: 35089095; PMCID: PMC8725579.
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Stephan T, Burgess SM, Cheng H, Danko CG, Gill CA, Jarvis ED, Koepfli KP, Koltes JE, Lyons E, Ronald P, Ryder OA, Schriml LM, Soltis P, VandeWoude S, Zhou H, Ostrander EA, Karlsson EK. Darwinian genomics and diversity in the tree of life. Proc Natl Acad Sci U S A. 2022;119(4). Epub 2022/01/20. doi: 10.1073/pnas.2115644119. PubMed PMID: 35042807; PMCID: PMC8795533.
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Sun Y, Hu L, Tao Z, Jarugumilli GK, Erb H, Singh A, Li Q, Cotton JL, Greninger P, Egan RK, Tony Ip Y, Benes CH, Che J, Mao J, Wu X. Pharmacological blockade of TEAD-YAP reveals its therapeutic limitation in cancer cells. Nat Commun. 2022;13(1):6744. Epub 2022/11/09. doi: 10.1038/s41467-022-34559-0. PubMed PMID: 36347861; PMCID: PMC9643419.
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Takasugi PR, Wang S, Truong KT, Drage EP, Kanishka SN, Higbee MA, Bamidele N, Ojelabi O, Sontheimer EJ, Gagnon JA. Orthogonal CRISPR-Cas tools for genome editing, inhibition, and CRISPR recording in zebrafish embryos. Genetics. 2022;220(1). Epub 2021/11/05. doi: 10.1093/genetics/iyab196. PubMed PMID: 34735006; PMCID: PMC8733422.
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Teebagy S, Wang Z, Dunlap D, Saleeba C, DiMezza D, Crain J, Lilly CM, Buchholz B, McManus DD, Hafer N. Understanding Healthcare Professionals' Perspectives on Point-of-Care Testing. Diagnostics (Basel). 2022;12(2). Epub 2022/02/26. doi: 10.3390/diagnostics12020533. PubMed PMID: 35204622; PMCID: PMC8870944.
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van 't Spijker HM, Stackpole EE, Almeida S, Katsara O, Liu B, Shen K, Schneider RJ, Gao FB, Richter JD. Ribosome profiling reveals novel regulation of C9ORF72 GGGGCC repeat-containing RNA translation. RNA. 2022;28(2):123-38. Epub 2021/12/02. doi: 10.1261/rna.078963.121. PubMed PMID: 34848561; PMCID: PMC8906550.
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Vasquez-Rifo A, Cook J, McEwan DL, Shikara D, Ausubel FM, Di Cara F, Cheng Z. ABCDs of the Relative Contributions of Pseudomonas aeruginosa Quorum Sensing Systems to Virulence in Diverse Nonvertebrate Hosts. mBio. 2022;13(2):e0041722. Epub 2022/03/22. doi: 10.1128/mbio.00417-22. PubMed PMID: 35311532; PMCID: PMC9040828.
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Vernia S, Lee A, Kennedy NJ, Han MS, Isasa M, Cavanagh-Kyros J, Roy A, Syed A, Chaudhry S, Edwards YJK, Gygi SP, Gao G, Davis RJ. Phosphorylation of RXRalpha mediates the effect of JNK to suppress hepatic FGF21 expression and promote metabolic syndrome. Proc Natl Acad Sci U S A. 2022;119(44):e2210434119. Epub 2022/10/26. doi: 10.1073/pnas.2210434119. PubMed PMID: 36282921; PMCID: PMC9636906.
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Vertii A, Ivshina M, Kant S, van Wijnen AJ. Editorial: The 4th dimension of the 3d chromatin organization: Dynamics and functional consequences. Front Cell Dev Biol. 2022;10:1065753. Epub 2022/11/18. doi: 10.3389/fcell.2022.1065753. PubMed PMID: 36393847; PMCID: PMC9641297.
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Vieira AFC, Xatse MA, Tifeki H, Diot C, Walhout AJM, Olsen CP. Monomethyl branched-chain fatty acids are critical for Caenorhabitis elegans survival in elevated glucose conditions. J Biol Chem. 2022;298(2):101444. Epub 2021/11/27. doi: 10.1016/j.jbc.2021.101444. PubMed PMID: 34826420; PMCID: PMC8819037.
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Vittoria MA, Kingston N, Kotynkova K, Xia E, Hong R, Huang L, McDonald S, Tilston-Lunel A, Darp R, Campbell JD, Lang D, Xu X, Ceol CJ, Varelas X, Ganem NJ. Inactivation of the Hippo tumor suppressor pathway promotes melanoma. Nat Commun. 2022;13(1):3732. Epub 2022/06/30. doi: 10.1038/s41467-022-31399-w. PubMed PMID: 35768444; PMCID: PMC9243107.
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Wang IH, Murray E, Andrews G, Jiang HC, Park SJ, Donnard E, Duran-Laforet V, Bear DM, Faust TE, Garber M, Baer CE, Schafer DP, Weng Z, Chen F, Macosko EZ, Greer PL. Spatial transcriptomic reconstruction of the mouse olfactory glomerular map suggests principles of odor processing. Nat Neurosci. 2022;25(4):484-92. Epub 2022/03/23. doi: 10.1038/s41593-022-01030-8. PubMed PMID: 35314823; PMCID: PMC9281876.
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Wang J, Zhang Y, Mendonca CA, Yukselen O, Muneeruddin K, Ren L, Liang J, Zhou C, Xie J, Li J, Jiang Z, Kucukural A, Shaffer SA, Gao G, Wang D. AAV-delivered suppressor tRNA overcomes a nonsense mutation in mice. Nature. 2022;604(7905):343-8. Epub 2022/03/25. doi: 10.1038/s41586-022-04533-3. PubMed PMID: 35322228; PMCID: PMC9446716.
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Wilcock DJ, Badrock AP, Wong CW, Owen R, Guerin M, Southam AD, Johnston H, Telfer BA, Fullwood P, Watson J, Ferguson H, Ferguson J, Lloyd GR, Jankevics A, Dunn WB, Wellbrock C, Lorigan P, Ceol C, Francavilla C, Smith MP, Hurlstone AFL. Oxidative stress from DGAT1 oncoprotein inhibition in melanoma suppresses tumor growth when ROS defenses are also breached. Cell Rep. 2022;39(12):110995. Epub 2022/06/23. doi: 10.1016/j.celrep.2022.110995. PubMed PMID: 35732120; PMCID: PMC9638004.
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Yang Loureiro Z, Solivan-Rivera J, Corvera S. Adipocyte Heterogeneity Underlying Adipose Tissue Functions. Endocrinology. 2022;163(1). Epub 2021/07/06. doi: 10.1210/endocr/bqab138. PubMed PMID: 34223880; PMCID: PMC8660558.
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Yenilmez B, Kelly M, Zhang GF, Wetoska N, Ilkayeva OR, Min K, Rowland L, DiMarzio C, He W, Raymond N, Lifshitz L, Pan M, Han X, Xie J, Friedline RH, Kim JK, Gao G, Herman MA, Newgard CB, Czech MP. Paradoxical activation of transcription factor SREBP1c and de novo lipogenesis by hepatocyte-selective ATP-citrate lyase depletion in obese mice. J Biol Chem. 2022;298(10):102401. Epub 2022/08/22. doi: 10.1016/j.jbc.2022.102401. PubMed PMID: 35988648; PMCID: PMC9490592.
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Yenilmez B, Wetoska N, Kelly M, Echeverria D, Min K, Lifshitz L, Alterman JF, Hassler MR, Hildebrand S, DiMarzio C, McHugh N, Vangjeli L, Sousa J, Pan M, Han X, Brehm MA, Khvorova A, Czech MP. An RNAi therapeutic targeting hepatic DGAT2 in a genetically obese mouse model of nonalcoholic steatohepatitis. Mol Ther. 2022;30(3):1329-42. Epub 2021/11/15. doi: 10.1016/j.ymthe.2021.11.007. PubMed PMID: 34774753; PMCID: PMC8899521.
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Zhang H, Bamidele N, Liu P, Ojelabi O, Gao XD, Rodriguez T, Cheng H, Kelly K, Watts JK, Xie J, Gao G, Wolfe SA, Xue W, Sontheimer EJ. Adenine Base Editing In Vivo with a Single Adeno-Associated Virus Vector. GEN Biotechnol. 2022;1(3):285-99. Epub 2022/07/12. doi: 10.1089/genbio.2022.0015. PubMed PMID: 35811581; PMCID: PMC9258002.
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