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Publications 2020

Armstrong J, Hickey G, Diekhans M, Fiddes IT, Novak AM, Deran A, Fang Q, Xie D, Feng S, Stiller J, Genereux D, Johnson J, Marinescu VD, Alfoldi J, Harris RS, Lindblad-Toh K, Haussler D, Karlsson E, Jarvis ED, Zhang G, Paten B. Progressive Cactus is a multiple-genome aligner for the thousand-genome era. Nature. 2020;587(7833):246-51. Epub 2020/11/13. doi: 10.1038/s41586-020-2871-y. PubMed PMID: 33177663; PMCID: PMC7673649.
https://www.ncbi.nlm.nih.gov/pubmed/33177663   

Batista TM, Dagdeviren S, Carroll SH, Cai W, Melnik VY, Noh HL, Saengnipanthkul S, Kim JK, Kahn CR, Lee RT. Arrestin domain-containing 3 (Arrdc3) modulates insulin action and glucose metabolism in liver. Proc Natl Acad Sci U S A. 2020;117(12):6733-40. Epub 2020/03/12. doi: 10.1073/pnas.1922370117. PubMed PMID: 32156724; PMCID: PMC7104271.
https://www.ncbi.nlm.nih.gov/pubmed/32156724   

Biscans A, Caiazzi J, Davis S, McHugh N, Sousa J, Khvorova A. The chemical structure and phosphorothioate content of hydrophobically modified siRNAs impact extrahepatic distribution and efficacy. Nucleic Acids Res. 2020;48(14):7665-80. Epub 2020/07/17. doi: 10.1093/nar/gkaa595. PubMed PMID: 32672813; PMCID: PMC7430635.
https://www.ncbi.nlm.nih.gov/pubmed/32672813   

Biscans A, Caiazzi J, McHugh N, Hariharan V, Muhuri M, Khvorova A. Docosanoic acid conjugation to siRNA enables functional and safe delivery to skeletal and cardiac muscles. Mol Ther. 2020. Epub 2020/12/22. doi: 10.1016/j.ymthe.2020.12.023. PubMed PMID: 33348054.
https://www.ncbi.nlm.nih.gov/pubmed/33348054   

Bose S, Volpatti LR, Thiono D, Yesilyurt V, McGladrigan C, Tang Y, Facklam A, Wang A, Jhunjhunwala S, Veiseh O, Hollister-Lock J, Bhattacharya C, Weir GC, Greiner DL, Langer R, Anderson DG. A retrievable implant for the long-term encapsulation and survival of therapeutic xenogeneic cells. Nat Biomed Eng. 2020;4(8):814-26. Epub 2020/04/02. doi: 10.1038/s41551-020-0538-5. PubMed PMID: 32231313.
https://www.ncbi.nlm.nih.gov/pubmed/32231313   

Calejman CM, Trefely S, Entwisle SW, Luciano A, Jung SM, Hsiao W, Torres A, Hung CM, Li H, Snyder NW, Villen J, Wellen KE, Guertin DA. Author Correction: mTORC2-AKT signaling to ATP-citrate lyase drives brown adipogenesis and de novo lipogenesis. Nat Commun. 2020;11(1):4585. Epub 2020/09/10. doi: 10.1038/s41467-020-18510-9. PubMed PMID: 32901020; PMCID: PMC7479589.
https://www.ncbi.nlm.nih.gov/pubmed/32901020   

Campuzano A, Zhang H, Ostroff GR, Dos Santos Dias L, Wuthrich M, Klein BS, Yu JJ, Lara HH, Lopez-Ribot JL, Hung CY. CARD9-Associated Dectin-1 and Dectin-2 Are Required for Protective Immunity of a Multivalent Vaccine against Coccidioides posadasii Infection. J Immunol. 2020;204(12):3296-306. Epub 2020/05/03. doi: 10.4049/jimmunol.1900793. PubMed PMID: 32358020; PMCID: PMC7323849.
https://www.ncbi.nlm.nih.gov/pubmed/32358020   

Carlisle AE, Lee N, Matthew-Onabanjo AN, Spears ME, Park SJ, Youkana D, Doshi MB, Peppers A, Li R, Joseph AB, Smith M, Simin K, Zhu LJ, Greer PL, Shaw LM, Kim D. Selenium detoxification is required for cancer-cell survival. Nat Metab. 2020;2(7):603-11. Epub 2020/07/23. doi: 10.1038/s42255-020-0224-7. PubMed PMID: 32694795; PMCID: PMC7455022.
https://www.ncbi.nlm.nih.gov/pubmed/32694795   

Carreiro S, Marvel-Coen J, Lee R, Chapman B, Ambros V. Circulating microRNA Profiles in Acetaminophen Toxicity. J Med Toxicol. 2020;16(2):177-87. Epub 2019/12/04. doi: 10.1007/s13181-019-00739-6. PubMed PMID: 31792846; PMCID: PMC7099119.
https://www.ncbi.nlm.nih.gov/pubmed/31792846   

Chang ML, Yang Z, Yang SS. Roles of Adipokines in Digestive Diseases: Markers of Inflammation, Metabolic Alteration and Disease Progression. Int J Mol Sci. 2020;21(21). Epub 2020/11/11. doi: 10.3390/ijms21218308. PubMed PMID: 33167521; PMCID: PMC7663948.
https://www.ncbi.nlm.nih.gov/pubmed/33167521   

Chauhan G, McClure J, Hekman J, Marsh PW, Bailey JA, Daniels RF, Genereux DP, Karlsson EK. Combining Citizen Science and Genomics to Investigate Tick, Pathogen, and Commensal Microbiome at Single-Tick Resolution. Front Genet. 2019;10:1322. Epub 2020/02/11. doi: 10.3389/fgene.2019.01322. PubMed PMID: 32038704; PMCID: PMC6985576.
https://www.ncbi.nlm.nih.gov/pubmed/32038704   

Chen HJ, Li Q, Nirala NK, Ip YT. The Snakeskin-Mesh Complex of Smooth Septate Junction Restricts Yorkie to Regulate Intestinal Homeostasis in Drosophila. Stem Cell Reports. 2020;14(5):828-44. Epub 2020/04/25. doi: 10.1016/j.stemcr.2020.03.021. PubMed PMID: 32330445; PMCID: PMC7220990.
https://www.ncbi.nlm.nih.gov/pubmed/32330445   

Cheung P, Xiol J, Dill MT, Yuan WC, Panero R, Roper J, Osorio FG, Maglic D, Li Q, Gurung B, Calogero RA, Yilmaz OH, Mao J, Camargo FD. Regenerative Reprogramming of the Intestinal Stem Cell State via Hippo Signaling Suppresses Metastatic Colorectal Cancer. Cell Stem Cell. 2020;27(4):590-604 e9. Epub 2020/07/31. doi: 10.1016/j.stem.2020.07.003. PubMed PMID: 32730753.
https://www.ncbi.nlm.nih.gov/pubmed/32730753   

Chrudinova M, Moreau F, Noh HL, Panikova T, Zakova L, Friedline RH, Valenzuela FA, Kim JK, Jiracek J, Kahn CR, Altindis E. Characterization of viral insulins reveals white adipose tissue-specific effects in mice. Mol Metab. 2020;44:101121. Epub 2020/11/22. doi: 10.1016/j.molmet.2020.101121. PubMed PMID: 33220491; PMCID: PMC7770979.
https://www.ncbi.nlm.nih.gov/pubmed/33220491   

Corrigan JK, Ramachandran D, He Y, Palmer CJ, Jurczak MJ, Chen R, Li B, Friedline RH, Kim JK, Ramsey JJ, Lantier L, McGuinness OP, Mouse Metabolic Phenotyping Center Energy Balance Working G, Banks AS. A big-data approach to understanding metabolic rate and response to obesity in laboratory mice. Elife. 2020;9. Epub 2020/05/02. doi: 10.7554/eLife.53560. PubMed PMID: 32356724; PMCID: PMC7274785.
https://www.ncbi.nlm.nih.gov/pubmed/32356724   

Crespo M, Gonzalez-Teran B, Nikolic I, Mora A, Folgueira C, Rodriguez E, Leiva-Vega L, Pintor-Chocano A, Fernandez-Chacon M, Ruiz-Garrido I, Cicuendez B, Tomas-Loba A, N AG, Caballero-Molano A, Beiroa D, Hernandez-Cosido L, Torres JL, Kennedy NJ, Davis RJ, Benedito R, Marcos M, Nogueiras R, Hidalgo A, Matesanz N, Leiva M, Sabio G. Neutrophil infiltration regulates clock-gene expression to organize daily hepatic metabolism. Elife. 2020;9. Epub 2020/12/09. doi: 10.7554/eLife.59258. PubMed PMID: 33287957; PMCID: PMC7723411.
https://www.ncbi.nlm.nih.gov/pubmed/33287957   

Cruz-Gordillo P, Honeywell ME, Harper NW, Leete T, Lee MJ. ELP-dependent expression of MCL1 promotes resistance to EGFR inhibition in triple-negative breast cancer cells. Sci Signal. 2020;13(658). Epub 2020/11/19. doi: 10.1126/scisignal.abb9820. PubMed PMID: 33203722; PMCID: PMC7685180.
https://www.ncbi.nlm.nih.gov/pubmed/33203722   

Csorgo B, Leon LM, Chau-Ly IJ, Vasquez-Rifo A, Berry JD, Mahendra C, Crawford ED, Lewis JD, Bondy-Denomy J. A compact Cascade-Cas3 system for targeted genome engineering. Nat Methods. 2020;17(12):1183-90. Epub 2020/10/21. doi: 10.1038/s41592-020-00980-w. PubMed PMID: 33077967.
https://www.ncbi.nlm.nih.gov/pubmed/33077967   

Cubero FJ, Mohamed MR, Woitok MM, Zhao G, Hatting M, Nevzorova YA, Chen C, Haybaeck J, de Bruin A, Avila MA, Boekschoten MV, Davis RJ, Trautwein C. Loss of c-Jun N-terminal Kinase 1 and 2 Function in Liver Epithelial Cells Triggers Biliary Hyperproliferation Resembling Cholangiocarcinoma. Hepatol Commun. 2020;4(6):834-51. Epub 2020/06/04. doi: 10.1002/hep4.1495. PubMed PMID: 32490320; PMCID: PMC7262317
https://www.ncbi.nlm.nih.gov/pubmed/32490320   

Czech MP. Mechanisms of insulin resistance related to white, beige, and brown adipocytes. Mol Metab. 2020;34:27-42. Epub 2020/03/18. doi: 10.1016/j.molmet.2019.12.014. PubMed PMID: 32180558; PMCID: PMC6997501.
https://www.ncbi.nlm.nih.gov/pubmed/32180558   

Damas J, Hughes GM, Keough KC, Painter CA, Persky NS, Corbo M, Hiller M, Koepfli KP, Pfenning AR, Zhao H, Genereux DP, Swofford R, Pollard KS, Ryder OA, Nweeia MT, Lindblad-Toh K, Teeling EC, Karlsson EK, Lewin HA. Broad host range of SARS-CoV-2 predicted by comparative and structural analysis of ACE2 in vertebrates. Proc Natl Acad Sci U S A. 2020;117(36):22311-22. Epub 2020/08/23. doi: 10.1073/pnas.2010146117. PubMed PMID: 32826334; PMCID: PMC7486773.
https://www.ncbi.nlm.nih.gov/pubmed/32826334   

Damas J, Hughes GM, Keough KC, Painter CA, Persky NS, Corbo M, Hiller M, Koepfli KP, Pfenning AR, Zhao H, Genereux DP, Swofford R, Pollard KS, Ryder OA, Nweeia MT, Lindblad-Toh K, Teeling EC, Karlsson EK, Lewin HA. Broad Host Range of SARS-CoV-2 Predicted by Comparative and Structural Analysis of ACE2 in Vertebrates. bioRxiv. 2020. Epub 2020/06/09. doi: 10.1101/2020.04.16.045302. PubMed PMID: 32511356; PMCID: PMC7263403.
https://www.ncbi.nlm.nih.gov/pubmed/32511356   

Darp R, Ceol C. Making a Melanoma: molecular and cellular changes underlying melanoma initiation. Pigment Cell Melanoma Res. 2020. Epub 2020/12/08. doi: 10.1111/pcmr.12950. PubMed PMID: 33283422.
https://www.ncbi.nlm.nih.gov/pubmed/33283422   

Das DK, Bulow U, Diehl WE, Durham ND, Senjobe F, Chandran K, Luban J, Munro JB. Conformational changes in the Ebola virus membrane fusion machine induced by pH, Ca2+, and receptor binding. PLoS Biol. 2020;18(2):e3000626. Epub 2020/02/11. doi: 10.1371/journal.pbio.3000626. PubMed PMID: 32040508; PMCID: PMC7034923.
https://www.ncbi.nlm.nih.gov/pubmed/32040508   

Davidson AR, Lu WT, Stanley SY, Wang J, Mejdani M, Trost CN, Hicks BT, Lee J, Sontheimer EJ. Anti-CRISPRs: Protein Inhibitors of CRISPR-Cas Systems. Annu Rev Biochem. 2020;89:309-32. Epub 2020/03/19. doi: 10.1146/annurev-biochem-011420-111224. PubMed PMID: 32186918.
https://www.ncbi.nlm.nih.gov/pubmed/32186918   

Desai PB, Stuck MW, Lv B, Pazour GJ. Ubiquitin links smoothened to intraflagellar transport to regulate Hedgehog signaling. J Cell Biol. 2020;219(7). Epub 2020/05/22. doi: 10.1083/jcb.201912104. PubMed PMID: 32435793; PMCID: PMC7337509.
https://www.ncbi.nlm.nih.gov/pubmed/32435793   

Dobson HE, Dias LDS, Kohn EM, Fites S, Wiesner DL, Dileepan T, Kujoth GC, Abraham A, Ostroff GR, Klein BS, Wuthrich M. Antigen discovery unveils resident memory and migratory cell roles in antifungal resistance. Mucosal Immunol. 2020;13(3):518-29. Epub 2020/01/05. doi: 10.1038/s41385-019-0244-3. PubMed PMID: 31900406; PMCID: PMC7183437.
https://www.ncbi.nlm.nih.gov/pubmed/31900406   

Durham ND, Howard AR, Govindan R, Senjobe F, Fels JM, Diehl WE, Luban J, Chandran K, Munro JB. Real-Time Analysis of Individual Ebola Virus Glycoproteins Reveals Pre-Fusion, Entry-Relevant Conformational Dynamics. Viruses. 2020;12(1). Epub 2020/01/19. doi: 10.3390/v12010103. PubMed PMID: 31952255; PMCID: PMC7019799.
https://www.ncbi.nlm.nih.gov/pubmed/31952255   

Fazzalari A, Basadonna G, Kucukural A, Tanriverdi K, Koupenova M, Pozzi N, Kakuturu J, Friedrich AU, Korstanje R, Fowler N, Belant JL, Beyer DE, Jr., Brooks MB, Dickson EW, Blackwood M, Mueller C, Palesty JA, Freedman JE, Cahan MA. A Translational Model for Venous Thromboembolism: MicroRNA Expression in Hibernating Black Bears. J Surg Res. 2021;257:203-12. Epub 2020/08/29. doi: 10.1016/j.jss.2020.06.027. PubMed PMID: 32858321.
https://www.ncbi.nlm.nih.gov/pubmed/32858321   

Frantz WT, Ceol CJ. From Tank to Treatment: Modeling Melanoma in Zebrafish. Cells. 2020;9(5). Epub 2020/05/28. doi: 10.3390/cells9051289. PubMed PMID: 32455885; PMCID: PMC7290816.
https://www.ncbi.nlm.nih.gov/pubmed/32455885   

Ghanta KS, Mello CC. Melting dsDNA Donor Molecules Greatly Improves Precision Genome Editing in Caenorhabditis elegans. Genetics. 2020;216(3):643-50. Epub 2020/09/24. doi: 10.1534/genetics.120.303564. PubMed PMID: 32963112; PMCID: PMC7648581.
https://www.ncbi.nlm.nih.gov/pubmed/32963112   

Giese GE, Walker MD, Ponomarova O, Zhang H, Li X, Minevich G, Walhout AJ. Caenorhabditis elegans methionine/S-adenosylmethionine cycle activity is sensed and adjusted by a nuclear hormone receptor. Elife. 2020;9. Epub 2020/10/06. doi: 10.7554/eLife.60259. PubMed PMID: 33016879; PMCID: PMC7561351.
https://www.ncbi.nlm.nih.gov/pubmed/33016879   

Gil A, Kamga L, Chirravuri-Venkata R, Aslan N, Clark F, Ghersi D, Luzuriaga K, Selin LK. Epstein-Barr Virus Epitope-Major Histocompatibility Complex Interaction Combined with Convergent Recombination Drives Selection of Diverse T Cell Receptor alpha and beta Repertoires. mBio. 2020;11(2). Epub 2020/03/19. doi: 10.1128/mBio.00250-20. PubMed PMID: 32184241; PMCID: PMC7078470.
https://www.ncbi.nlm.nih.gov/pubmed/32184241   

Goodman RP, Markhard AL, Shah H, Sharma R, Skinner OS, Clish CB, Deik A, Patgiri A, Hsu YH, Masia R, Noh HL, Suk S, Goldberger O, Hirschhorn JN, Yellen G, Kim JK, Mootha VK. Hepatic NADH reductive stress underlies common variation in metabolic traits. Nature. 2020;583(7814):122-6. Epub 2020/05/29. doi: 10.1038/s41586-020-2337-2. PubMed PMID: 32461692; PMCID: PMC7536642.
https://www.ncbi.nlm.nih.gov/pubmed/32461692   

Guilherme A, Yenilmez B, Bedard AH, Henriques F, Liu D, Lee A, Goldstein L, Kelly M, Nicoloro SM, Chen M, Weinstein L, Collins S, Czech MP. Control of Adipocyte Thermogenesis and Lipogenesis through beta3-Adrenergic and Thyroid Hormone Signal Integration. Cell Rep. 2020;31(5):107598. Epub 2020/05/07. doi: 10.1016/j.celrep.2020.107598. PubMed PMID: 32375048; PMCID: PMC7676427.
https://www.ncbi.nlm.nih.gov/pubmed/32375048   

Gupta R, Malvi P, Parajuli KR, Janostiak R, Bugide S, Cai G, Zhu LJ, Green MR, Wajapeyee N. KLF7 promotes pancreatic cancer growth and metastasis by up-regulating ISG expression and maintaining Golgi complex integrity. Proc Natl Acad Sci U S A. 2020;117(22):12341-51. Epub 2020/05/21. doi: 10.1073/pnas.2005156117. PubMed PMID: 32430335; PMCID: PMC7275752.
https://www.ncbi.nlm.nih.gov/pubmed/32430335   

Han L, Choudhury S, Mich-Basso JD, Ammanamanchi N, Ganapathy B, Suresh S, Khaladkar M, Singh J, Maehr R, Zuppo DA, Kim J, Eberwine JH, Wyman SK, Wu YL, Kuhn B. Lamin B2 Levels Regulate Polyploidization of Cardiomyocyte Nuclei and Myocardial Regeneration. Dev Cell. 2020;53(1):42-59 e11. Epub 2020/02/29. doi: 10.1016/j.devcel.2020.01.030. PubMed PMID: 32109383; PMCID: PMC7346764.
https://www.ncbi.nlm.nih.gov/pubmed/32109383   

Han MS, Perry RJ, Camporez JP, Scherer PE, Shulman GI, Gao G, Davis RJ. A feed-forward regulatory loop in adipose tissue promotes signaling by the hepatokine FGF21. Genes Dev. 2021;35(1-2):133-46. Epub 2020/12/19. doi: 10.1101/gad.344556.120. PubMed PMID: 33334822.
https://www.ncbi.nlm.nih.gov/pubmed/33334822   

Han MS, White A, Perry RJ, Camporez JP, Hidalgo J, Shulman GI, Davis RJ. Regulation of adipose tissue inflammation by interleukin 6. Proc Natl Acad Sci U S A. 2020;117(6):2751-60. Epub 2020/01/26. doi: 10.1073/pnas.1920004117. PubMed PMID: 31980524; PMCID: PMC7022151.
https://www.ncbi.nlm.nih.gov/pubmed/31980524   

Hayden CA, Landrock D, Hung CY, Ostroff G, Fake GM, Walker JH, Kier A, Howard JA. Co-Administration of Injected and Oral Vaccine Candidates Elicits Improved Immune Responses over Either Route Alone. Vaccines (Basel). 2020;8(1). Epub 2020/01/25. doi: 10.3390/vaccines8010037. PubMed PMID: 31973150; PMCID: PMC7157212.
https://www.ncbi.nlm.nih.gov/pubmed/31973150   

Henriques F, Bedard AH, Guilherme A, Kelly M, Chi J, Zhang P, Lifshitz LM, Bellve K, Rowland LA, Yenilmez B, Kumar S, Wang Y, Luban J, Weinstein LS, Lin JD, Cohen P, Czech MP. Single-Cell RNA Profiling Reveals Adipocyte to Macrophage Signaling Sufficient to Enhance Thermogenesis. Cell Rep. 2020;32(5):107998. Epub 2020/08/07. doi: 10.1016/j.celrep.2020.107998. PubMed PMID: 32755590; PMCID: PMC7433376.
https://www.ncbi.nlm.nih.gov/pubmed/32755590   

Hester MM, Lee CK, Abraham A, Khoshkenar P, Ostroff GR, Levitz SM, Specht CA. Protection of mice against experimental cryptococcosis using glucan particle-based vaccines containing novel recombinant antigens. Vaccine. 2020;38(3):620-6. Epub 2019/11/09. doi: 10.1016/j.vaccine.2019.10.051. PubMed PMID: 31699504; PMCID: PMC6954324.
https://www.ncbi.nlm.nih.gov/pubmed/31699504   

Hien A, Molinaro G, Liu B, Huber KM, Richter JD. Ribosome profiling in mouse hippocampus: plasticity-induced regulation and bidirectional control by TSC2 and FMRP. Mol Autism. 2020;11(1):78. Epub 2020/10/16. doi: 10.1186/s13229-020-00384-9. PubMed PMID: 33054857; PMCID: PMC7556950.
https://www.ncbi.nlm.nih.gov/pubmed/33054857   

Holdorf AD, Higgins DP, Hart AC, Boag PR, Pazour GJ, Walhout AJM, Walker AK. WormCat: An Online Tool for Annotation and Visualization of Caenorhabditis elegans Genome-Scale Data. Genetics. 2020;214(2):279-94. Epub 2019/12/08. doi: 10.1534/genetics.119.302919. PubMed PMID: 31810987; PMCID: PMC7017019.
https://www.ncbi.nlm.nih.gov/pubmed/31810987   

Hsiao WY, Jung SM, Tang Y, Haley JA, Li R, Li H, Calejman CM, Sanchez-Gurmaches J, Hung CM, Luciano AK, DeMambro V, Wellen KE, Rosen CJ, Zhu LJ, Guertin DA. The Lipid Handling Capacity of Subcutaneous Fat Is Programmed by mTORC2 during Development. Cell Rep. 2020;33(1):108223. Epub 2020/10/08. doi: 10.1016/j.celrep.2020.108223. PubMed PMID: 33027655; PMCID: PMC7607535.
https://www.ncbi.nlm.nih.gov/pubmed/33027655   

Iwanaga R, Truong BT, Hsu JY, Lambert KA, Vyas R, Orlicky D, Shellman YG, Tan AC, Ceol C, Artinger KB. Loss of prdm1a accelerates melanoma onset and progression. Mol Carcinog. 2020;59(9):1052-63. Epub 2020/06/21. doi: 10.1002/mc.23236. PubMed PMID: 32562448.
https://www.ncbi.nlm.nih.gov/pubmed/32562448   

Jiang L, Wang YJ, Zhao J, Uehara M, Hou Q, Kasinath V, Ichimura T, Banouni N, Dai L, Li X, Greiner DL, Shultz LD, Zhang X, Sun ZJ, Curtin I, Vangos NE, Yeoh ZC, Geffken EA, Seo HS, Liu ZX, Heffron GJ, Shah K, Dhe-Paganon S, Abdi R. Direct Tumor Killing and Immunotherapy through Anti-SerpinB9 Therapy. Cell. 2020;183(5):1219-33 e18. Epub 2020/11/27. doi: 10.1016/j.cell.2020.10.045. PubMed PMID: 33242418.
https://www.ncbi.nlm.nih.gov/pubmed/33242418   

Jiang T, Henderson JM, Coote K, Cheng Y, Valley HC, Zhang XO, Wang Q, Rhym LH, Cao Y, Newby GA, Bihler H, Mense M, Weng Z, Anderson DG, McCaffrey AP, Liu DR, Xue W. Chemical modifications of adenine base editor mRNA and guide RNA expand its application scope. Nat Commun. 2020;11(1):1979. Epub 2020/04/26. doi: 10.1038/s41467-020-15892-8. PubMed PMID: 32332735; PMCID: PMC7181807.
https://www.ncbi.nlm.nih.gov/pubmed/32332735   

Krietenstein N, Abraham S, Venev SV, Abdennur N, Gibcus J, Hsieh TS, Parsi KM, Yang L, Maehr R, Mirny LA, Dekker J, Rando OJ. Ultrastructural Details of Mammalian Chromosome Architecture. Mol Cell. 2020;78(3):554-65 e7. Epub 2020/03/28. doi: 10.1016/j.molcel.2020.03.003. PubMed PMID: 32213324; PMCID: PMC7222625.
https://www.ncbi.nlm.nih.gov/pubmed/32213324   

Kwan SY, Sheel A, Song CQ, Zhang XO, Jiang T, Dang H, Cao Y, Ozata DM, Mou H, Yin H, Weng Z, Wang XW, Xue W. Depletion of TRRAP Induces p53-Independent Senescence in Liver Cancer by Down-Regulating Mitotic Genes. Hepatology. 2020;71(1):275-90. Epub 2019/06/13. doi: 10.1002/hep.30807. PubMed PMID: 31188495; PMCID: PMC6906267.
https://www.ncbi.nlm.nih.gov/pubmed/31188495   

Lawson ND, Li R, Shin M, Grosse A, Yukselen O, Stone OA, Kucukural A, Zhu L. An improved zebrafish transcriptome annotation for sensitive and comprehensive detection of cell type-specific genes. Elife. 2020;9. Epub 2020/08/25. doi: 10.7554/eLife.55792. PubMed PMID: 32831172; PMCID: PMC7486121.
https://www.ncbi.nlm.nih.gov/pubmed/32831172   

Leech CM, Flynn MJ, Arsenault HE, Ou J, Liu H, Zhu LJ, Benanti JA. The coordinate actions of calcineurin and Hog1 mediate the stress response through multiple nodes of the cell cycle network. PLoS Genet. 2020;16(4):e1008600. Epub 2020/04/29. doi: 10.1371/journal.pgen.1008600. PubMed PMID: 32343701; PMCID: PMC7209309.
https://www.ncbi.nlm.nih.gov/pubmed/32343701   

Leite NC, Sintov E, Meissner TB, Brehm MA, Greiner DL, Harlan DM, Melton DA. Modeling Type 1 Diabetes In Vitro Using Human Pluripotent Stem Cells. Cell Rep. 2020;32(2):107894. Epub 2020/07/16. doi: 10.1016/j.celrep.2020.107894. PubMed PMID: 32668238; PMCID: PMC7359783.
https://www.ncbi.nlm.nih.gov/pubmed/32668238   

Lemieux JE, Siddle KJ, Shaw BM, Loreth C, Schaffner SF, Gladden-Young A, Adams G, Fink T, Tomkins-Tinch CH, Krasilnikova LA, DeRuff KC, Rudy M, Bauer MR, Lagerborg KA, Normandin E, Chapman SB, Reilly SK, Anahtar MN, Lin AE, Carter A, Myhrvold C, Kemball ME, Chaluvadi S, Cusick C, Flowers K, Neumann A, Cerrato F, Farhat M, Slater D, Harris JB, Branda JA, Hooper D, Gaeta JM, Baggett TP, O'Connell J, Gnirke A, Lieberman TD, Philippakis A, Burns M, Brown CM, Luban J, Ryan ET, Turbett SE, LaRocque RC, Hanage WP, Gallagher GR, Madoff LC, Smole S, Pierce VM, Rosenberg E, Sabeti PC, Park DJ, MacInnis BL. Phylogenetic analysis of SARS-CoV-2 in Boston highlights the impact of superspreading events. Science. 2020. Epub 2020/12/12. doi: 10.1126/science.abe3261. PubMed PMID: 33303686.
https://www.ncbi.nlm.nih.gov/pubmed/33303686   

Li HJ, Ray SK, Kucukural A, Gradwohl G, Leiter AB. Reduced Neurog3 Gene Dosage Shifts Enteroendocrine Progenitor Towards Goblet Cell Lineage in the Mouse Intestine. Cell Mol Gastroenterol Hepatol. 2020. Epub 2020/08/22. doi: 10.1016/j.jcmgh.2020.08.006. PubMed PMID: 32822913.
https://www.ncbi.nlm.nih.gov/pubmed/32822913   

Li J, Lambright DG, Hsu VW. Coordination of Grp1 recruitment mechanisms by its phosphorylation. Mol Biol Cell. 2020;31(25):2816-25. Epub 2020/10/08. doi: 10.1091/mbc.E20-03-0173. PubMed PMID: 33026967.
https://www.ncbi.nlm.nih.gov/pubmed/33026967   

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Tsuji J, Thomson T, Chan E, Brown CK, Oppenheimer J, Bigelow C, Dong X, Theurkauf WE, Weng Z, Schwartz LM. High-resolution analysis of differential gene expression during skeletal muscle atrophy and programmed cell death. Physiol Genomics. 2020;52(10):492-511. Epub 2020/09/15. doi: 10.1152/physiolgenomics.00047.2020. PubMed PMID: 32926651; PMCID: PMC7750511.
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Walker RG, Barrandon O, Poggioli T, Dagdeviren S, Carroll SH, Mills MJ, Mendello KR, Gomez Y, Loffredo FS, Pancoast JR, Macias-Trevino C, Marts C, LeClair KB, Noh HL, Kim T, Banks AS, Kim JK, Cohen DE, Wagers AJ, Melton DA, Lee RT. Exogenous GDF11, but not GDF8, reduces body weight and improves glucose homeostasis in mice. Sci Rep. 2020;10(1):4561. Epub 2020/03/14. doi: 10.1038/s41598-020-61443-y. PubMed PMID: 32165710; PMCID: PMC7067781.
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