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Publications 2019

Allen TM, Brehm MA, Bridges S, Ferguson S, Kumar P, Mirochnitchenko O, Palucka K, Pelanda R, Sanders-Beer B, Shultz LD, Su L, PrabhuDas M. Humanized immune system mouse models: progress, challenges and opportunities. Nat Immunol. 2019;20(7):770-4. Epub 2019/06/05. doi: 10.1038/s41590-019-0416-z. PubMed PMID: 31160798.
https://www.ncbi.nlm.nih.gov/pubmed/31160798 

Alterman JF, Godinho B, Hassler MR, Ferguson CM, Echeverria D, Sapp E, Haraszti RA, Coles AH, Conroy F, Miller R, Roux L, Yan P, Knox EG, Turanov AA, King RM, Gernoux G, Mueller C, Gray-Edwards HL, Moser RP, Bishop NC, Jaber SM, Gounis MJ, Sena-Esteves M, Pai AA, DiFiglia M, Aronin N, Khvorova A. A divalent siRNA chemical scaffold for potent and sustained modulation of gene expression throughout the central nervous system. Nat Biotechnol. 2019;37(8):884-94. Epub 2019/08/04. doi: 10.1038/s41587-019-0205-0. PubMed PMID: 31375812; PMCID: PMC6879195.
https://www.ncbi.nlm.nih.gov/pubmed/31375812    

Batista TM, Garcia-Martin R, Cai W, Konishi M, O'Neill BT, Sakaguchi M, Kim JH, Jung DY, Kim JK, Kahn CR. Multi-dimensional Transcriptional Remodeling by Physiological Insulin In Vivo. Cell Rep. 2019;26(12):3429-43 e3. Epub 2019/03/21. doi: 10.1016/j.celrep.2019.02.081. PubMed PMID: 30893613; PMCID: PMC6543850. https://www.ncbi.nlm.nih.gov/pubmed/30893613 

Beichman AC, Koepfli KP, Li G, Murphy W, Dobrynin P, Kliver S, Tinker MT, Murray MJ, Johnson J, Lindblad-Toh K, Karlsson EK, Lohmueller KE, Wayne RK. Aquatic Adaptation and Depleted Diversity: A Deep Dive into the Genomes of the Sea Otter and Giant Otter. Mol Biol Evol. 2019;36(12):2631-55. Epub 2019/06/19. doi: 10.1093/molbev/msz101. PubMed PMID: 31212313.
https://www.ncbi.nlm.nih.gov/pubmed/31212313 

Biscans A, Coles A, Echeverria D, Khvorova A. The valency of fatty acid conjugates impacts siRNA pharmacokinetics, distribution, and efficacy in vivo. J Control Release. 2019;302:116-25. Epub 2019/04/04. doi: 10.1016/j.jconrel.2019.03.028. PubMed PMID: 30940496; PMCID: PMC6546539. https://www.ncbi.nlm.nih.gov/pubmed/30940496

Biscans A, Coles A, Haraszti R, Echeverria D, Hassler M, Osborn M, Khvorova A. Diverse lipid conjugates for functional extra-hepatic siRNA delivery in vivo. Nucleic Acids Res. 2019;47(3):1082-96. Epub 2018/12/14. doi: 10.1093/nar/gky1239. PubMed PMID: 30544191; PMCID: PMC6379722.
https://www.ncbi.nlm.nih.gov/pubmed/30544191 

Blaszczak AM, Wright VP, Anandani K, Liu J, Jalilvand A, Bergin S, Nicoloro SM, Czech MP, Lafuse W, Deng T, Bradley D, Hsueh WA. Loss of Antigen Presentation in Adipose Tissue Macrophages or in Adipocytes, but Not Both, Improves Glucose Metabolism. J Immunol. 2019;202(8):2451-9. Epub 2019/03/10. doi: 10.4049/jimmunol.1801470. PubMed PMID: 30850480.
https://www.ncbi.nlm.nih.gov/pubmed/30850480    

Boucher JI, Whitfield TW, Dauphin A, Nachum G, Hollins C, Zeldovich KB, Swanstrom R, Schiffer CA, Luban J, Bolon DNA. Constrained Mutational Sampling of Amino Acids in HIV-1 Protease Evolution. Mol Biol Evol. 2019;36(4):798-810. Epub 2019/02/06. doi: 10.1093/molbev/msz022. PubMed PMID: 30721995. https://www.ncbi.nlm.nih.gov/pubmed/30721995   

Braun MC, Castillo-Ruiz A, Indic P, Jung DY, Kim JK, Brown RH, Jr., Swoap SJ, Schwartz WJ. Defective daily temperature regulation in a mouse model of amyotrophic lateral sclerosis. Exp Neurol. 2019;311:305-12. Epub 2018/07/22. doi: 10.1016/j.expneurol.2018.07.008. PubMed PMID: 30031021; PMCID: PMC6263852. https://www.ncbi.nlm.nih.gov/pubmed/30031021   

Bulcha JT, Giese GE, Ali MZ, Lee YU, Walker MD, Holdorf AD, Yilmaz LS, Brewster RC, Walhout AJM. A Persistence Detector for Metabolic Network Rewiring in an Animal. Cell Rep. 2019;26(2):460-8 e4. Epub 2019/01/10. doi: 10.1016/j.celrep.2018.12.064. PubMed PMID: 30625328; PMCID: PMC6368391. https://www.ncbi.nlm.nih.gov/pubmed/30625328

Carreiro S, Marvel-Coen J, Lee R, Chapman B, Ambros V. Circulating microRNA Profiles in Acetaminophen Toxicity. J Med Toxicol. 2019. Epub 2019/12/04. doi: 10.1007/s13181-019-00739-6. PubMed PMID: 31792846.
https://www.ncbi.nlm.nih.gov/pubmed/31792846 

Casewell NR, Petras D, Card DC, Suranse V, Mychajliw AM, Richards D, Koludarov I, Albulescu LO, Slagboom J, Hempel BF, Ngum NM, Kennerley RJ, Brocca JL, Whiteley G, Harrison RA, Bolton FMS, Debono J, Vonk FJ, Alfoldi J, Johnson J, Karlsson EK, Lindblad-Toh K, Mellor IR, Sussmuth RD, Fry BG, Kuruppu S, Hodgson WC, Kool J, Castoe TA, Barnes I, Sunagar K, Undheim EAB, Turvey ST. Solenodon genome reveals convergent evolution of venom in eulipotyphlan mammals. Proc Natl Acad Sci U S A. 2019;116(51):25745-55. Epub 2019/11/28. doi: 10.1073/pnas.1906117116. PubMed PMID: 31772017; PMCID: PMC6926037. https://www.ncbi.nlm.nih.gov/pubmed/31772017

Charuchaibovorn S, Sanprasert V, Sutthanont N, Hu Y, Abraham A, Ostroff GR, Aroian RV, Jaleta TG, Lok JB, Nuchprayoon S. Bacillus thuringiensis Cry5B is Active against Strongyloides stercoralis in vitro. Am J Trop Med Hyg. 2019;101(5):1177-82. Epub 2019/09/14. doi: 10.4269/ajtmh.19-0083. PubMed PMID: 31516117; PMCID: PMC6838580.
https://www.ncbi.nlm.nih.gov/pubmed/31516117 

Chiramel AI, Meyerson NR, McNally KL, Broeckel RM, Montoya VR, Mendez-Solis O, Robertson SJ, Sturdevant GL, Lubick KJ, Nair V, Youseff BH, Ireland RM, Bosio CM, Kim K, Luban J, Hirsch VM, Taylor RT, Bouamr F, Sawyer SL, Best SM. TRIM5alpha Restricts Flavivirus Replication by Targeting the Viral Protease for Proteasomal Degradation. Cell Rep. 2019;27(11):3269-83 e6. Epub 2019/06/13. doi: 10.1016/j.celrep.2019.05.040. PubMed PMID: 31189110.
https://www.ncbi.nlm.nih.gov/pubmed/31189110    

Choi S, Ambros V. The C. elegans heterochronic gene lin-28 coordinates the timing of hypodermal and somatic gonadal programs for hermaphrodite reproductive system morphogenesis. Development. 2019;146(5). Epub 2019/02/13. doi: 10.1242/dev.164293. PubMed PMID: 30745431; PMCID: PMC6432661. https://www.ncbi.nlm.nih.gov/pubmed/30745431   

Chowdhury M, Li CF, He Z, Lu Y, Liu XS, Wang YF, Ip YT, Strand MR, Yu XQ. Toll family members bind multiple Spatzle proteins and activate antimicrobial peptide gene expression in Drosophila. J Biol Chem. 2019;294(26):10172-81. Epub 2019/05/16. doi: 10.1074/jbc.RA118.006804. PubMed PMID: 31088910.
https://www.ncbi.nlm.nih.gov/pubmed/31088910    

D'Agostino L, Nie Y, Goswami S, Tong K, Yu S, Bandyopadhyay S, Flores J, Zhang X, Balasubramanian I, Joseph I, Sakamori R, Farrell V, Li Q, Yang CS, Gao B, Ferraris RP, Yehia G, Bonder EM, Goldenring JR, Verzi MP, Zhang L, Ip YT, Gao N. Recycling Endosomes in Mature Epithelia Restrain Tumorigenic Signaling. Cancer Res. 2019;79(16):4099-112. Epub 2019/06/27. doi: 10.1158/0008-5472.CAN-18-4075. PubMed PMID: 31239271; PMCID: PMC6726494.
https://www.ncbi.nlm.nih.gov/pubmed/31239271 

Dahan O, Dorfman BS, Sayin S, Rosener B, Hua T, Yarden A, Mitchell A. Harnessing robotic automation and web-based technologies to modernize scientific outreach. PLoS Biol. 2019;17(6):e3000348. Epub 2019/06/27. doi: 10.1371/journal.pbio.3000348. PubMed PMID: 31242174.
https://www.ncbi.nlm.nih.gov/pubmed/31242174    

Das S, Malaby AW, Nawrotek A, Zhang W, Zeghouf M, Maslen S, Skehel M, Chakravarthy S, Irving TC, Bilsel O, Cherfils J, Lambright DG. Structural Organization and Dynamics of Homodimeric Cytohesin Family Arf GTPase Exchange Factors in Solution and on Membranes. Structure. 2019;27(12):1782-97 e7. Epub 2019/10/12. doi: 10.1016/j.str.2019.09.007. PubMed PMID: 31601460; PMCID: PMC6948192.
https://www.ncbi.nlm.nih.gov/pubmed/31601460 

Dittmann A, Kennedy NJ, Soltero NL, Morshed N, Mana MD, Yilmaz OH, Davis RJ, White FM. High-fat diet in a mouse insulin-resistant model induces widespread rewiring of the phosphotyrosine signaling network. Mol Syst Biol. 2019;15(8):e8849. Epub 2019/08/30. doi: 10.15252/msb.20198849. PubMed PMID: 31464373; PMCID: PMC6674232.
https://www.ncbi.nlm.nih.gov/pubmed/31464373 

Duan J, Lambright DG. TRAPPing a Rab GTPase by the Tail. Dev Cell. 2019;48(1):9-11. Epub 2019/01/09. doi: 10.1016/j.devcel.2018.12.008. PubMed PMID: 30620905. https://www.ncbi.nlm.nih.gov/pubmed/30620905   

Dumas SN, Guo CA, Kim JK, Friedline RH, Ntambi JM. Interleukin-6 derived from cutaneous deficiency of stearoyl-CoA desaturase- 1 may mediate metabolic organ crosstalk among skin, adipose tissue and liver. Biochem Biophys Res Commun. 2019;508(1):87-91. Epub 2018/11/25. doi: 10.1016/j.bbrc.2018.11.083. PubMed PMID: 30470572; PMCID: PMC6309575.
https://www.ncbi.nlm.nih.gov/pubmed/30470572    

Edraki A, Mir A, Ibraheim R, Gainetdinov I, Yoon Y, Song CQ, Cao Y, Gallant J, Xue W, Rivera-Perez JA, Sontheimer EJ. A Compact, High-Accuracy Cas9 with a Dinucleotide PAM for In Vivo Genome Editing. Mol Cell. 2019;73(4):714-26 e4. Epub 2018/12/26. doi: 10.1016/j.molcel.2018.12.003. PubMed PMID: 30581144; PMCID: PMC6386616.
https://www.ncbi.nlm.nih.gov/pubmed/30581144 

Ehrhardt N, Cui J, Dagdeviren S, Saengnipanthkul S, Goodridge HS, Kim JK, Lantier L, Guo X, Chen YI, Raffel LJ, Buchanan TA, Hsueh WA, Rotter JI, Goodarzi MO, Peterfy M. Adiposity-Independent Effects of Aging on Insulin Sensitivity and Clearance in Mice and Humans. Obesity (Silver Spring). 2019;27(3):434-43. Epub 2019/02/26. doi: 10.1002/oby.22418. PubMed PMID: 30801985; PMCID: PMC6474357.
https://www.ncbi.nlm.nih.gov/pubmed/30801985    

Elaimy AL, Amante JJ, Zhu LJ, Wang M, Walmsley CS, FitzGerald TJ, Goel HL, Mercurio AM. The VEGF receptor neuropilin 2 promotes homologous recombination by stimulating YAP/TAZ-mediated Rad51 expression. Proc Natl Acad Sci U S A. 2019;116(28):14174-80. Epub 2019/06/27. doi: 10.1073/pnas.1821194116. PubMed PMID: 31235595; PMCID: PMC6628806.
https://www.ncbi.nlm.nih.gov/pubmed/31235595 

Elfawal MA, Savinov SN, Aroian RV. Drug Screening for Discovery of Broad-spectrum Agents for Soil-transmitted Nematodes. Sci Rep. 2019;9(1):12347. Epub 2019/08/28. doi: 10.1038/s41598-019-48720-1. PubMed PMID: 31451730; PMCID: PMC6710243.
https://www.ncbi.nlm.nih.gov/pubmed/31451730 

Farah S, Doloff JC, Muller P, Sadraei A, Han HJ, Olafson K, Vyas K, Tam HH, Hollister-Lock J, Kowalski PS, Griffin M, Meng A, McAvoy M, Graham AC, McGarrigle J, Oberholzer J, Weir GC, Greiner DL, Langer R, Anderson DG. Long-term implant fibrosis prevention in rodents and non-human primates using crystallized drug formulations. Nat Mater. 2019. Epub 2019/06/27. doi: 10.1038/s41563-019-0377-5. PubMed PMID: 31235902.
https://www.ncbi.nlm.nih.gov/pubmed/31235902    

Feldman JL, Peterson CL. Yeast Sirtuin Family Members Maintain Transcription Homeostasis to Ensure Genome Stability. Cell Rep. 2019;27(10):2978-89 e5. Epub 2019/06/06. doi: 10.1016/j.celrep.2019.05.009. PubMed PMID: 31167142. https://www.ncbi.nlm.nih.gov/pubmed/31167142   

Fernandez S, Viola JM, Torres A, Wallace M, Trefely S, Zhao S, Affronti HC, Gengatharan JM, Guertin DA, Snyder NW, Metallo CM, Wellen KE. Adipocyte ACLY Facilitates Dietary Carbohydrate Handling to Maintain Metabolic Homeostasis in Females. Cell Rep. 2019;27(9):2772-84 e6. Epub 2019/05/30. doi: 10.1016/j.celrep.2019.04.112. PubMed PMID: 31141698; PMCID: PMC6608748. https://www.ncbi.nlm.nih.gov/pubmed/31141698   

Fischer DS, Fiedler AK, Kernfeld EM, Genga RMJ, Bastidas-Ponce A, Bakhti M, Lickert H, Hasenauer J, Maehr R, Theis FJ. Inferring population dynamics from single-cell RNA-sequencing time series data. Nat Biotechnol. 2019;37(4):461-8. Epub 2019/04/03. doi: 10.1038/s41587-019-0088-0. PubMed PMID: 30936567. https://www.ncbi.nlm.nih.gov/pubmed/30936567   

Fitzgibbons TP, Lee N, Tran KV, Nicoloro S, Kelly M, Tam SK, Czech MP. Coronary disease is not associated with robust alterations in inflammatory gene expression in human epicardial fat. JCI Insight. 2019;4(20). Epub 2019/09/13. doi: 10.1172/jci.insight.124859. PubMed PMID: 31513547; PMCID: PMC6824304. https://www.ncbi.nlm.nih.gov/pubmed/31513547

Garcia B, Lee J, Edraki A, Hidalgo-Reyes Y, Erwood S, Mir A, Trost CN, Seroussi U, Stanley SY, Cohn RD, Claycomb JM, Sontheimer EJ, Maxwell KL, Davidson AR. Anti-CRISPR AcrIIA5 Potently Inhibits All Cas9 Homologs Used for Genome Editing. Cell Rep. 2019;29(7):1739-46 e5. Epub 2019/11/14. doi: 10.1016/j.celrep.2019.10.017. PubMed PMID: 31722192; PMCID: PMC6910239. https://www.ncbi.nlm.nih.gov/pubmed/31722192

Gawron MA, Duval M, Carbone C, Jaiswal S, Wallace A, Martin JC, 3rd, Dauphin A, Brehm MA, Greiner DL, Shultz LD, Luban J, Cavacini LA. Human Anti-HIV-1 gp120 Monoclonal Antibodies with Neutralizing Activity Cloned from Humanized Mice Infected with HIV-1. J Immunol. 2019;202(3):799-804. Epub 2018/12/30. doi: 10.4049/jimmunol.1801085. PubMed PMID: 30593536; PMCID: PMC6344273. https://www.ncbi.nlm.nih.gov/pubmed/30593536   

Genga RMJ, Kernfeld EM, Parsi KM, Parsons TJ, Ziller MJ, Maehr R. Single-Cell RNA-Sequencing-Based CRISPRi Screening Resolves Molecular Drivers of Early Human Endoderm Development. Cell Rep. 2019;27(3):708-18 e10. Epub 2019/04/18. doi: 10.1016/j.celrep.2019.03.076. PubMed PMID: 30995470; PMCID: PMC6525305. https://www.ncbi.nlm.nih.gov/pubmed/30995470   

Ghadieh HE, Russo L, Muturi HT, Ghanem SS, Manaserh IH, Noh HL, Suk S, Kim JK, Hill JW, Najjar SM. Hyperinsulinemia drives hepatic insulin resistance in male mice with liver-specific Ceacam1 deletion independently of lipolysis. Metabolism. 2019;93:33-43. Epub 2019/01/22. doi: 10.1016/j.metabol.2019.01.008. PubMed PMID: 30664851; PMCID: PMC6401268. https://www.ncbi.nlm.nih.gov/pubmed/30664851   

Gramann AK, Venkatesan AM, Guerin M, Ceol CJ. Regulation of zebrafish melanocyte development by ligand-dependent BMP signaling. Elife. 2019;8. Epub 2019/12/24. doi: 10.7554/eLife.50047. PubMed PMID: 31868592.
https://www.ncbi.nlm.nih.gov/pubmed/31868592 

Greer PL, Samuel MA. Becoming a Principal Investigator: Designing and Navigating Your Academic Adventure. Neuron. 2019;103(6):959-63. Epub 2019/09/27. doi: 10.1016/j.neuron.2019.08.023. PubMed PMID: 31557459.
https://www.ncbi.nlm.nih.gov/pubmed/31557459 

Guilherme A, Henriques F, Bedard AH, Czech MP. Molecular pathways linking adipose innervation to insulin action in obesity and diabetes mellitus. Nat Rev Endocrinol. 2019;15(4):207-25. Epub 2019/02/09. doi: 10.1038/s41574-019-0165-y. PubMed PMID: 30733616.
https://www.ncbi.nlm.nih.gov/pubmed/30733616    

Guo S, Pridham KJ, Virbasius CM, He B, Zhang L, Varmark H, Green MR, Sheng Z.  A large-scale RNA interference screen identifies genes that regulate autophagy at different stages. Sci Rep. 2019;9(1):8382. Epub 2019/06/12. doi: 10.1038/s41598-019-42889-1. PubMed PMID: 31182720; PMCID: PMC6557834. https://www.ncbi.nlm.nih.gov/pubmed/31182720 

Hamza Z, El-Hashash M, Aly S, Hathout A, Soto E, Sabry B, Ostroff G. Preparation and characterization of yeast cell wall beta-glucan encapsulated humic acid nanoparticles as an enhanced aflatoxin B1 binder. Carbohydr Polym. 2019;203:185-92. Epub 2018/10/16. doi: 10.1016/j.carbpol.2018.08.047. PubMed PMID: 30318202. https://www.ncbi.nlm.nih.gov/pubmed/30318202   

Haraszti RA, Miller R, Dubuke ML, Rockwell HE, Coles AH, Sapp E, Didiot MC, Echeverria D, Stoppato M, Sere YY, Leszyk J, Alterman JF, Godinho B, Hassler MR, McDaniel J, Narain NR, Wollacott R, Wang Y, Shaffer SA, Kiebish MA, DiFiglia M, Aronin N, Khvorova A. Serum Deprivation of Mesenchymal Stem Cells Improves Exosome Activity and Alters Lipid and Protein Composition. iScience. 2019;16:230-41. Epub 2019/06/14. doi: 10.1016/j.isci.2019.05.029. PubMed PMID: 31195240; PMCID: PMC6562145.
https://www.ncbi.nlm.nih.gov/pubmed/31195240   

Hayden CA, Hung CY, Zhang H, Negron A, Esquerra R, Ostroff G, Abraham A, Lopez AG, Gonzales JE, Howard JA. Maize-Produced Ag2 as a Subunit Vaccine for Valley Fever. J Infect Dis. 2019. Epub 2019/06/12. doi: 10.1093/infdis/jiz196. PubMed PMID: 31184702.
https://www.ncbi.nlm.nih.gov/pubmed/31184702    

Heijink AM, Everts M, Honeywell ME, Richards R, Kok YP, de Vries EGE, Lee MJ, van Vugt M. Modeling of Cisplatin-Induced Signaling Dynamics in Triple-Negative Breast Cancer Cells Reveals Mediators of Sensitivity. Cell Rep. 2019;28(9):2345-57 e5. Epub 2019/08/29. doi: 10.1016/j.celrep.2019.07.070. PubMed PMID: 31461651; PMCID: PMC6718811.
https://www.ncbi.nlm.nih.gov/pubmed/31461651 

Hester MM, Lee CK, Abraham A, Khoshkenar P, Ostroff GR, Levitz SM, Specht CA. Protection of mice against experimental cryptococcosis using glucan particle-based vaccines containing novel recombinant antigens. Vaccine. 2020;38(3):620-6. Epub 2019/11/09. doi: 10.1016/j.vaccine.2019.10.051. PubMed PMID: 31699504; PMCID: PMC6954324.
https://www.ncbi.nlm.nih.gov/pubmed/31699504

Hsiao WY, Guertin DA. De Novo Lipogenesis as a Source of Second Messengers in Adipocytes. Curr Diab Rep. 2019;19(11):138. Epub 2019/11/22. doi: 10.1007/s11892-019-1264-9. PubMed PMID: 31749022.
https://www.ncbi.nlm.nih.gov/pubmed/3174902 

Hurtado Del Pozo C, Ruiz HH, Arivazhagan L, Aranda JF, Shim C, Daya P, Derk J, MacLean M, He M, Frye L, Friedline RH, Noh HL, Kim JK, Friedman RA, Ramasamy R, Schmidt AM. A Receptor of the Immunoglobulin Superfamily Regulates Adaptive Thermogenesis. Cell Rep. 2019;28(3):773-91 e7. Epub 2019/07/18. doi: 10.1016/j.celrep.2019.06.061. PubMed PMID: 31315054.
https://www.ncbi.nlm.nih.gov/pubmed/31315054    

Ilbay O, Ambros V. Pheromones and Nutritional Signals Regulate the Developmental Reliance on let-7 Family MicroRNAs in C. elegans. Curr Biol. 2019;29(11):1735-45 e4. Epub 2019/05/21. doi: 10.1016/j.cub.2019.04.034. PubMed PMID: 31104929. https://www.ncbi.nlm.nih.gov/pubmed/31104929   

Ilbay O, Ambros V. Regulation of nuclear-cytoplasmic partitioning by the lin-28-lin-46 pathway reinforces microRNA repression of HBL-1 to confer robust cell-fate progression in C. elegans. Development. 2019;146(21). Epub 2019/10/11. doi: 10.1242/dev.183111. PubMed PMID: 31597658; PMCID: PMC6857590.
https://www.ncbi.nlm.nih.gov/pubmed/31597658 

Jangalwe S, Kapoor VN, Xu J, Girnius N, Kennedy NJ, Edwards YJK, Welsh RM, Davis RJ, Brehm MA. Cutting Edge: Early Attrition of Memory T Cells during Inflammation and Costimulation Blockade Is Regulated Concurrently by Proapoptotic Proteins Fas and Bim. J Immunol. 2019;202(3):647-51. Epub 2019/01/06. doi: 10.4049/jimmunol.1800278. PubMed PMID: 30610162; PMCID: PMC6344249. https://www.ncbi.nlm.nih.gov/pubmed/30610162   

Jin YJ, Byun S, Han S, Chamberlin J, Kim D, Kim MJ, Lee Y. Differential alternative splicing regulation among hepatocellular carcinoma with different risk factors. BMC Med Genomics. 2019;12(Suppl 8):175. Epub 2019/12/21. doi: 10.1186/s12920-019-0635-z. PubMed PMID: 31856847; PMCID: PMC6923823.
https://www.ncbi.nlm.nih.gov/pubmed/31856847 

Jung SM, Hung CM, Hildebrand SR, Sanchez-Gurmaches J, Martinez-Pastor B, Gengatharan JM, Wallace M, Mukhopadhyay D, Martinez Calejman C, Luciano AK, Hsiao WY, Tang Y, Li H, Daniels DL, Mostoslavsky R, Metallo CM, Guertin DA. Non-canonical mTORC2 Signaling Regulates Brown Adipocyte Lipid Catabolism through SIRT6-FoxO1. Mol Cell. 2019;75(4):807-22 e8. Epub 2019/08/24. doi: 10.1016/j.molcel.2019.07.023. PubMed PMID: 31442424.
https://www.ncbi.nlm.nih.gov/pubmed/31442424   

Jung SM, Sanchez-Gurmaches J, Guertin DA. Brown Adipose Tissue Development and Metabolism. Handb Exp Pharmacol. 2019;251:3-36. Epub 2018/09/12. doi: 10.1007/164_2018_168. PubMed PMID: 30203328.
https://www.ncbi.nlm.nih.gov/pubmed/30203328    

Kamga L, Gil A, Song I, Brody R, Ghersi D, Aslan N, Stern LJ, Selin LK, Luzuriaga K. CDR3alpha drives selection of the immunodominant Epstein Barr virus (EBV) BRLF1-specific CD8 T cell receptor repertoire in primary infection. PLoS Pathog. 2019;15(11):e1008122. Epub 2019/11/26. doi: 10.1371/journal.ppat.1008122. PubMed PMID: 31765434; PMCID: PMC6901265. https://www.ncbi.nlm.nih.gov/pubmed/31765434

Kant S, Craige SM, Chen K, Reif MM, Learnard H, Kelly M, Caliz AD, Tran KV, Ramo K, Peters OM, Freeman M, Davis RJ, Keaney JF, Jr. Neural JNK3 regulates blood flow recovery after hindlimb ischemia in mice via an Egr1/Creb1 axis. Nat Commun. 2019;10(1):4223. Epub 2019/09/19. doi: 10.1038/s41467-019-11982-4. PubMed PMID: 31530804; PMCID: PMC6748991.
https://www.ncbi.nlm.nih.gov/pubmed/31530804 

Karlinsey JE, Stepien TA, Mayho M, Singletary LA, Bingham-Ramos LK, Brehm MA, Greiner DL, Shultz LD, Gallagher LA, Bawn M, Kingsley RA, Libby SJ, Fang FC. Genome-wide Analysis of Salmonella enterica serovar Typhi in Humanized Mice Reveals Key Virulence Features. Cell Host Microbe. 2019;26(3):426-34 e6. Epub 2019/08/27. doi: 10.1016/j.chom.2019.08.001. PubMed PMID: 31447308; PMCID: PMC6742556.
https://www.ncbi.nlm.nih.gov/pubmed/31447308 

Kim DW, Chang C, Chen X, Doran AC, Gaudreault F, Wager T, DeMarco GJ, Kim JK. Systems approach reveals photosensitivity and PER2 level as determinants of clock-modulator efficacy. Mol Syst Biol. 2019;15(7):e8838. Epub 2019/07/30. doi: 10.15252/msb.20198838. PubMed PMID: 31353796; PMCID: PMC6613017. https://www.ncbi.nlm.nih.gov/pubmed/31353796

Kim K, Dauphin A, Komurlu S, McCauley SM, Yurkovetskiy L, Carbone C, Diehl WE, Strambio-De-Castillia C, Campbell EM, Luban J. Cyclophilin A protects HIV-1 from restriction by human TRIM5alpha. Nat Microbiol. 2019;4(12):2044-51. Epub 2019/10/23. doi: 10.1038/s41564-019-0592-5. PubMed PMID: 31636416; PMCID: PMC6879858.
https://www.ncbi.nlm.nih.gov/pubmed/31636416 

Kucukural A, Yukselen O, Ozata DM, Moore MJ, Garber M. DEBrowser: interactive differential expression analysis and visualization tool for count data. BMC Genomics. 2019;20(1):6. Epub 2019/01/07. doi: 10.1186/s12864-018-5362-x. PubMed PMID: 30611200; PMCID: PMC6321710.
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Kwan SY, Sheel A, Song CQ, Zhang XO, Jiang T, Dang H, Cao Y, Ozata DM, Mou H, Yin H, Weng Z, Wang XW, Xue W. Depletion of TRRAP induces p53-independent senescence in liver cancer by downregulating mitotic genes. Hepatology. 2019. Epub 2019/06/13. doi: 10.1002/hep.30807. PubMed PMID: 31188495. https://www.ncbi.nlm.nih.gov/pubmed/31188495   

Lamers SL, Fogel GB, Nolan DJ, Barbier AE, Rose R, Singer EJ, Gonzalez-Perez MP, McGrath MS. Emerging Patterns in HIV-1 gp120 Variable Domains in Anatomical Tissues in the Absence of a Plasma Viral Load. AIDS Res Hum Retroviruses. 2019;35(6):588-96. Epub 2019/02/23. doi: 10.1089/AID.2018.0267. PubMed PMID: 30793919; PMCID: PMC6588100.
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Lee J, Mou H, Ibraheim R, Liang SQ, Liu P, Xue W, Sontheimer EJ. Tissue-restricted genome editing in vivo specified by microRNA-repressible anti-CRISPR proteins. RNA. 2019;25(11):1421-31. Epub 2019/08/24. doi: 10.1261/rna.071704.119. PubMed PMID: 31439808; PMCID: PMC6795140.
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Li F, Miao L, Xue T, Qin H, Mondal S, Thompson PR, Coonrod SA, Liu X, Zhang X. Inhibiting PAD2 enhances the anti-tumor effect of docetaxel in tamoxifen-resistant breast cancer cells. J Exp Clin Cancer Res. 2019;38(1):414. Epub 2019/10/12. doi: 10.1186/s13046-019-1404-8. PubMed PMID: 31601253; PMCID: PMC6785896. https://www.ncbi.nlm.nih.gov/pubmed/31601253

Li H, Li Q, Dang K, Ma S, Cotton JL, Yang S, Zhu LJ, Deng AC, Ip YT, Johnson RL, Wu X, Punzo C, Mao J. YAP/TAZ Activation Drives Uveal Melanoma Initiation and Progression. Cell Rep. 2019;29(10):3200-11 e4. Epub 2019/12/05. doi: 10.1016/j.celrep.2019.03.021. PubMed PMID: 31801083.
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Li Q, Nirala NK, Chen HJ, Nie Y, Wang W, Zhang B, Czech MP, Wang Q, Xu L, Mao J, Ip YT. The Misshapen subfamily of Ste20 kinases regulate proliferation in the aging mammalian intestinal epithelium. J Cell Physiol. 2019. Epub 2019/05/02. doi: 10.1002/jcp.28756. PubMed PMID: 31042012.
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Liu B, Molinaro G, Shu H, Stackpole EE, Huber KM, Richter JD. Optimization of ribosome profiling using low-input brain tissue from fragile X syndrome model mice. Nucleic Acids Res. 2019;47(5):e25. Epub 2018/12/28. doi: 10.1093/nar/gky1292. PubMed PMID: 30590705; PMCID: PMC6411937.
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Liu J, Wang T, Creighton CJ, Wu SP, Ray M, Janardhan KS, Willson CJ, Cho SN, Castro PD, Ittmann MM, Li JL, Davis RJ, DeMayo FJ. JNK(1/2) represses Lkb(1)-deficiency-induced lung squamous cell carcinoma progression. Nat Commun. 2019;10(1):2148. Epub 2019/05/16. doi: 10.1038/s41467-019-09843-1. PubMed PMID: 31089135; PMCID: PMC6517592.
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Liu P, Luk K, Shin M, Idrizi F, Kwok S, Roscoe B, Mintzer E, Suresh S, Morrison K, Frazao JB, Bolukbasi MF, Ponnienselvan K, Luban J, Zhu LJ, Lawson ND, Wolfe SA. Enhanced Cas12a editing in mammalian cells and zebrafish. Nucleic Acids Res. 2019;47(8):4169-80. Epub 2019/03/21. doi: 10.1093/nar/gkz184. PubMed PMID: 30892626; PMCID: PMC6486634.
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Lord KA, Larson G, Coppinger RP, Karlsson EK. The History of Farm Foxes Undermines the Animal Domestication Syndrome. Trends Ecol Evol. 2019. Epub 2019/12/08. doi: 10.1016/j.tree.2019.10.011. PubMed PMID: 31810775.
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Luban J. The hidden cost of genetic resistance to HIV-1. Nat Med. 2019;25(11):1796. Epub 2019/10/09. doi: 10.1038/s41591-019-0636-7. PubMed PMID: 31595085. https://www.ncbi.nlm.nih.gov/pubmed/31595085  

Luban J. The hidden cost of genetic resistance to HIV-1. Nat Med. 2019;25(6):878-9. Epub 2019/06/05. doi: 10.1038/s41591-019-0481-8. PubMed PMID: 31160816. https://www.ncbi.nlm.nih.gov/pubmed/31160816 

Luciano AK, Guertin DA. Oncogenic AKTivation by methylation. Nat Cell Biol. 2019;21(2):114-5. Epub 2019/01/30. doi: 10.1038/s41556-019-0275-8. PubMed PMID: 30692624. https://www.ncbi.nlm.nih.gov/pubmed/30692624   

Ma L, Pak ML, Ou J, Yu J, St Louis P, Shan Y, Hutchinson L, Li S, Brehm MA, Zhu LJ, Green MR. Prosurvival kinase PIM2 is a therapeutic target for eradication of chronic myeloid leukemia stem cells. Proc Natl Acad Sci U S A. 2019;116(21):10482-7. Epub 2019/05/10. doi: 10.1073/pnas.1903550116. PubMed PMID: 31068472; PMCID: PMC6535024.
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Mataix-Cols D, Hansen B, Mattheisen M, Karlsson EK, Addington AM, Boberg J, Djurfeldt DR, Halvorsen M, Lichtenstein P, Solem S, Lindblad-Toh K, Nordic OCD, Related Disorders C, Haavik J, Kvale G, Ruck C, Crowley JJ. Nordic OCD & Related Disorders Consortium: Rationale, design, and methods. Am J Med Genet B Neuropsychiatr Genet. 2020;183(1):38-50. Epub 2019/08/20. doi: 10.1002/ajmg.b.32756. PubMed PMID: 31424634; PMCID: PMC6898732.
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McDougall WM, Perreira JM, Hung HF, Vertii A, Xiaofei E, Zimmerman W, Kowalik TF, Doxsey S, Brass AL. Viral Infection or IFN-alpha Alters Mitotic Spindle Orientation by Modulating Pericentrin Levels. iScience. 2019;12:270-9. Epub 2019/02/05. doi: 10.1016/j.isci.2019.01.025. PubMed PMID: 30716700; PMCID: PMC6360249. https://www.ncbi.nlm.nih.gov/pubmed/30716700   

McManus M, Henderson J, Gautam A, Brody R, Weiss ER, Persaud D, Mick E, Luzuriaga K, Investigators P. Quantitative Human Immunodeficiency Virus (HIV)-1 Antibodies Correlate With Plasma HIV-1 RNA and Cell-associated DNA Levels in Children on Antiretroviral Therapy. Clin Infect Dis. 2019;68(10):1725-32. Epub 2019/01/23. doi: 10.1093/cid/ciy753. PubMed PMID: 30668843; PMCID: PMC6495016. https://www.ncbi.nlm.nih.gov/pubmed/30668843   

Megquier K, Genereux DP, Hekman J, Swofford R, Turner-Maier J, Johnson J, Alonso J, Li X, Morrill K, Anguish LJ, Koltookian M, Logan B, Sharp CR, Ferrer L, Lindblad-Toh K, Meyers-Wallen VN, Hoffman A, Karlsson EK. BarkBase: Epigenomic Annotation of Canine Genomes. Genes (Basel). 2019;10(6). Epub 2019/06/12. doi: 10.3390/genes10060433. PubMed PMID: 31181663.
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Megquier K, Turner-Maier J, Swofford R, Kim JH, Sarver AL, Wang C, Sakthikumar S, Johnson J, Koltookian M, Lewellen M, Scott MC, Schulte AJ, Borst L, Tonomura N, Alfoldi J, Painter C, Thomas R, Karlsson EK, Breen M, Modiano JF, Elvers I, Lindblad-Toh K. Comparative Genomics Reveals Shared Mutational Landscape in Canine Hemangiosarcoma and Human Angiosarcoma. Mol Cancer Res. 2019;17(12):2410-21. Epub 2019/10/02. doi: 10.1158/1541-7786.MCR-19-0221. PubMed PMID: 31570656.
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Min SY, Desai A, Yang Z, Sharma A, DeSouza T, Genga RMJ, Kucukural A, Lifshitz LM, Nielsen S, Scheele C, Maehr R, Garber M, Corvera S. Diverse repertoire of human adipocyte subtypes develops from transcriptionally distinct mesenchymal progenitor cells. Proc Natl Acad Sci U S A. 2019;116(36):17970-9. Epub 2019/08/20. doi: 10.1073/pnas.1906512116. PubMed PMID: 31420514; PMCID: PMC6731669.
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Min SY, Learnard H, Kant S, Gealikman O, Rojas-Rodriguez R, DeSouza T, Desai A, Keaney JF, Jr., Corvera S, Craige SM. Exercise Rescues Gene Pathways Involved in Vascular Expansion and Promotes Functional Angiogenesis in Subcutaneous White Adipose Tissue. Int J Mol Sci. 2019;20(8). Epub 2019/04/28. doi: 10.3390/ijms20082046. PubMed PMID: 31027261; PMCID: PMC6515240. https://www.ncbi.nlm.nih.gov/pubmed/31027261   

Mookerjee-Basu J, Hua X, Ge L, Nicolas E, Li Q, Czyzewicz P, Zhongping D, Peri S, FuxmanBass JI, Walhout AJM, Kappes DJ. Functional Conservation of a Developmental Switch in Mammals since the Jurassic Age. Mol Biol Evol. 2019;36(1):39-53. Epub 2018/10/09. doi: 10.1093/molbev/msy191. PubMed PMID: 30295892; PMCID: PMC6340473.
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Mou H, Ozata DM, Smith JL, Sheel A, Kwan SY, Hough S, Kucukural A, Kennedy Z, Cao Y, Xue W. CRISPR-SONIC: targeted somatic oncogene knock-in enables rapid in vivo cancer modeling. Genome Med. 2019;11(1):21. Epub 2019/04/17. doi: 10.1186/s13073-019-0627-9. PubMed PMID: 30987660; PMCID: PMC6466773. https://www.ncbi.nlm.nih.gov/pubmed/30987660   

Muniraju M, Mutsvunguma LZ, Foley J, Escalante GM, Rodriguez E, Nabiee R, Totonchy J, Mulama DH, Nyagol J, Wussow F, Barasa AK, Brehm M, Ogembo JG. Kaposi Sarcoma-associated Herpesvirus Glycoprotein H is Indispensable for Infection of Epithelial, Endothelial, and Fibroblast Cell Types. J Virol. 2019. Epub 2019/05/31. doi: 10.1128/JVI.00630-19. PubMed PMID: 31142670.
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Nelson C, Ambros V. Trans-splicing of the C. elegans let-7 primary transcript developmentally regulates let-7 microRNA biogenesis and let-7 family microRNA activity. Development. 2019;146(5). Epub 2019/02/17. doi: 10.1242/dev.172031. PubMed PMID: 30770392; PMCID: PMC6432665.
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Nie Y, Yu S, Li Q, Nirala NK, Amcheslavsky A, Edwards YJK, Shum PW, Jiang Z, Wang W, Zhang B, Gao N, Ip YT. Oncogenic Pathways and Loss of the Rab11 GTPase Synergize To Alter Metabolism in Drosophila. Genetics. 2019;212(4):1227-39. Epub 2019/06/20. doi: 10.1534/genetics.119.302137. PubMed PMID: 31213502; PMCID: PMC6707446.
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Noon JB, Schwarz EM, Ostroff GR, Aroian RV. A highly expressed intestinal cysteine protease of Ancylostoma ceylanicum protects vaccinated hamsters from hookworm infection. PLoS Negl Trop Dis. 2019;13(4):e0007345. Epub 2019/04/23. doi: 10.1371/journal.pntd.0007345. PubMed PMID: 31009474; PMCID: PMC6497320. https://www.ncbi.nlm.nih.gov/pubmed/31009474   

Ou J, Zhu LJ. trackViewer: a Bioconductor package for interactive and integrative visualization of multi-omics data. Nat Methods. 2019;16(6):453-4. Epub 2019/05/28. doi: 10.1038/s41592-019-0430-y. PubMed PMID: 31133757.
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Pan SC, Ward DV, Yin Y, Hu Y, Elfawal MA, Clark RE, Aroian RV. Cognitive and Microbiome Impacts of Experimental Ancylostoma ceylanicum Hookworm Infections in Hamsters. Sci Rep. 2019;9(1):7868. Epub 2019/05/28. doi: 10.1038/s41598-019-44301-4. PubMed PMID: 31133690; PMCID: PMC6536493. https://www.ncbi.nlm.nih.gov/pubmed/31133690    

Parhad SS, Theurkauf WE. Rapid evolution and conserved function of the piRNA pathway. Open Biol. 2019;9(1):180181. Epub 2019/04/09. doi: 10.1098/rsob.180181. PubMed PMID: 30958115; PMCID: PMC6367137.
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Park CS, Lewis AH, Chen TJ, Bridges CS, Shen Y, Suppipat K, Puppi M, Tomolonis JA, Pang PD, Mistretta TA, Ma L, Green MR, Rau R, Lacorazza HD. A KLF4-DYRK2-mediated pathway regulating self-renewal in CML stem cells. Blood. 2019;134(22):1960-72. Epub 2019/09/14. doi: 10.1182/blood.2018875922. PubMed PMID: 31515251.
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Parthibane V, Acharya D, Srideshikan SM, Lin J, Myerscough DG, Abimannan T, Vijaykrishna N, Blankenberg D, Bondada L, Klarmann KD, Fox SD, Andresson T, Tessarollo L, Acharya U, Keller JR, Acharya JK. Sptlc1 is essential for myeloid differentiation and hematopoietic homeostasis. Blood Adv. 2019;3(22):3635-49. Epub 2019/11/22. doi: 10.1182/bloodadvances.2019000729. PubMed PMID: 31751474; PMCID: PMC6880889.
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Pazour GJ, King SM. Ciliary Doublet Microtubules at Near-Atomic Resolution. Cell. 2019;179(4):805-7. Epub 2019/11/02. doi: 10.1016/j.cell.2019.10.013. PubMed PMID: 31675493. https://www.ncbi.nlm.nih.gov/pubmed/31675493  

Pazour GJ, Quarmby L, Smith AO, Desai PB, Schmidts M. Cilia in cystic kidney and other diseases. Cell Signal. 2019:109519. Epub 2019/12/28. doi: 10.1016/j.cellsig.2019.109519. PubMed PMID: 31881326; PMCID: PMC6953175. https://www.ncbi.nlm.nih.gov/pubmed/31881326  

Picariello T, Brown JM, Hou Y, Swank G, Cochran DA, King OD, Lechtreck K, Pazour GJ, Witman GB. A global analysis of IFT-A function reveals specialization for transport of membrane-associated proteins into cilia. J Cell Sci. 2019;132(3). Epub 2019/01/20. doi: 10.1242/jcs.220749. PubMed PMID: 30659111; PMCID: PMC6382014.
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Qu M, Lu P, Bevell K, Fogarty K, Lifshitz L, Shi F, ZhuGe R. Smooth muscle cell-specific TMEM16A deletion does not alter Ca2+ signaling, uterine contraction, gestation length or litter size in micedagger. Biol Reprod. 2019. Epub 2019/06/09. doi: 10.1093/biolre/ioz096. PubMed PMID: 31175367.
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Quitadamo B, Peters PJ, Koch M, Luzuriaga K, Cheng-Mayer C, Clapham PR, Gonzalez-Perez MP. No detection of CD4-independent human immunodeficiency virus 1 envelope glycoproteins in brain tissue of patients with or without neurological complications. Arch Virol. 2019;164(2):473-82. Epub 2018/11/12. doi: 10.1007/s00705-018-4094-1. PubMed PMID: 30415390; PMCID: PMC6369005. https://www.ncbi.nlm.nih.gov/pubmed/30415390   

Redick SD, Leehy L, Rittenhouse AR, Blodgett DM, Derr AG, Kucukural A, Garber MG, Shultz LD, Greiner DL, Wang JP, Harlan DM, Bortell R, Jurczyk A. Recovery of viable endocrine-specific cells and transcriptomes from human pancreatic islet-engrafted mice. FASEB J. 2020;34(1):1901-11. Epub 2020/01/10. doi: 10.1096/fj.201901022RR. PubMed PMID: 31914605.
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Rojas-Rodriguez R, Lujan-Hernandez J, Min SY, DeSouza T, Teebagy P, Desai A, Tessier H, Slamin R, Siegel-Reamer L, Berg C, Baez A, Lalikos J, Corvera S. Generation of Functional Human Adipose Tissue in Mice from Primed Progenitor Cells. Tissue Eng Part A. 2019;25(11-12):842-54. Epub 2018/10/12. doi: 10.1089/ten.TEA.2018.0067. PubMed PMID: 30306830; PMCID: PMC6590775.
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Rovira Gonzalez YI, Moyer AL, LeTexier NJ, Bratti AD, Feng S, Sun C, Liu T, Mula J, Jha P, Iyer SR, Lovering RM, O'Rourke B, Noh HL, Suk S, Kim JK, Essien Umanah GK, Wagner KR. Mss51 deletion enhances muscle metabolism and glucose homeostasis in mice. JCI Insight. 2019;4(20). Epub 2019/09/19. doi: 10.1172/jci.insight.122247. PubMed PMID: 31527314; PMCID: PMC6824300.
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Russell MA, Redick SD, Blodgett DM, Richardson SJ, Leete P, Krogvold L, Dahl-Jorgensen K, Bottino R, Brissova M, Spaeth JM, Babon JAB, Haliyur R, Powers AC, Yang C, Kent SC, Derr AG, Kucukural A, Garber MG, Morgan NG, Harlan DM. HLA Class II Antigen Processing and Presentation Pathway Components Demonstrated by Transcriptome and Protein Analyses of Islet beta-Cells From Donors With Type 1 Diabetes. Diabetes. 2019;68(5):988-1001. Epub 2019/03/06. doi: 10.2337/db18-0686. PubMed PMID: 30833470; PMCID: PMC6477908. https://www.ncbi.nlm.nih.gov/pubmed/30833470   

Sanchez-Gurmaches J, Martinez Calejman C, Jung SM, Li H, Guertin DA. Brown fat organogenesis and maintenance requires AKT1 and AKT2. Mol Metab. 2019;23:60-74. Epub 2019/03/06. doi: 10.1016/j.molmet.2019.02.004. PubMed PMID: 30833219; PMCID: PMC6480051.
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Shen K, Rogala KB, Chou HT, Huang RK, Yu Z, Sabatini DM. Cryo-EM Structure of the Human FLCN-FNIP2-Rag-Ragulator Complex. Cell. 2019;179(6):1319-29 e8. Epub 2019/11/11. doi: 10.1016/j.cell.2019.10.036. PubMed PMID: 31704029. https://www.ncbi.nlm.nih.gov/pubmed/31704029  

Shi L, Zhou T, Huang Q, Zhang S, Li W, Zhang L, Hess RA, Pazour GJ, Zhang Z. Intraflagellar transport protein 74 is essential for spermatogenesis and male fertility in micedagger. Biol Reprod. 2019;101(1):188-99. Epub 2019/04/21. doi: 10.1093/biolre/ioz071. PubMed PMID: 31004481; PMCID: PMC6614581.
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Shientag LJ, Cabrera OA, Pazour GJ. Allelic Diversity in the Serum Amyloid A2 Gene and Amyloid A Amyloidosis in a Breeding Colony of Zebra Finches (Taeniopygia guttata). Comp Med. 2019;69(5):425-31. Epub 2019/08/30. doi: 10.30802/AALAS-CM-18-000139. PubMed PMID: 31462347; PMCID: PMC6807727. https://www.ncbi.nlm.nih.gov/pubmed/31462347  

Shraga A, Olshvang E, Davidzohn N, Khoshkenar P, Germain N, Shurrush K, Carvalho S, Avram L, Albeck S, Unger T, Lefker B, Subramanyam C, Hudkins RL, Mitchell A, Shulman Z, Kinoshita T, London N. Covalent Docking Identifies a Potent and Selective MKK7 Inhibitor. Cell Chem Biol. 2019;26(1):98-108 e5. Epub 2018/11/20. doi: 10.1016/j.chembiol.2018.10.011. PubMed PMID: 30449673. https://www.ncbi.nlm.nih.gov/pubmed/30449673  

Singh RK, Fan J, Gioacchini N, Watanabe S, Bilsel O, Peterson CL. Transient Kinetic Analysis of SWR1C-Catalyzed H2A.Z Deposition Unravels the Impact of Nucleosome Dynamics and the Asymmetry of Histone Exchange. Cell Rep. 2019;27(2):374-86 e4. Epub 2019/04/11. doi: 10.1016/j.celrep.2019.03.035. PubMed PMID: 30970243; PMCID: PMC6545893.
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Soldatov R, Kaucka M, Kastriti ME, Petersen J, Chontorotzea T, Englmaier L, Akkuratova N, Yang Y, Haring M, Dyachuk V, Bock C, Farlik M, Piacentino ML, Boismoreau F, Hilscher MM, Yokota C, Qian X, Nilsson M, Bronner ME, Croci L, Hsiao WY, Guertin DA, Brunet JF, Consalez GG, Ernfors P, Fried K, Kharchenko PV, Adameyko I. Spatiotemporal structure of cell fate decisions in murine neural crest. Science. 2019;364(6444). Epub 2019/06/07. doi: 10.1126/science.aas9536. PubMed PMID: 31171666.
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Song CQ, Jiang T, Richter M, Rhym LH, Koblan LW, Zafra MP, Schatoff EM, Doman JL, Cao Y, Dow LE, Zhu LJ, Anderson DG, Liu DR, Yin H, Xue W. Adenine base editing in an adult mouse model of tyrosinaemia. Nat Biomed Eng. 2019. Epub 2019/11/20. doi: 10.1038/s41551-019-0357-8. PubMed PMID: 31740768.
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Stackpole EE, Akins MR, Ivshina M, Murthy AC, Fawzi NL, Fallon JR. EGFP insertional mutagenesis reveals multiple FXR2P fibrillar states with differing ribosome association in neurons. Biol Open. 2019;8(8). Epub 2019/08/23. doi: 10.1242/bio.046383. PubMed PMID: 31434643; PMCID: PMC6737979.
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Stanney W, 3rd, Ladam F, Donaldson IJ, Parsons TJ, Maehr R, Bobola N, Sagerstrom CG. Combinatorial action of NF-Y and TALE at embryonic enhancers defines distinct gene expression programs during zygotic genome activation in zebrafish. Dev Biol. 2019. Epub 2019/12/22. doi: 10.1016/j.ydbio.2019.12.003. PubMed PMID: 31862379. https://www.ncbi.nlm.nih.gov/pubmed/31862379  

Sztul E, Chen PW, Casanova JE, Cherfils J, Dacks JB, Lambright DG, Lee FS, Randazzo PA, Santy LC, Schurmann A, Wilhelmi I, Yohe ME, Kahn RA. ARF GTPases and their GEFs and GAPs: concepts and challenges. Mol Biol Cell. 2019;30(11):1249-71. Epub 2019/05/16. doi: 10.1091/mbc.E18-12-0820. PubMed PMID: 31084567. https://www.ncbi.nlm.nih.gov/pubmed/31084567   

Thavalingam A, Cheng Z, Garcia B, Huang X, Shah M, Sun W, Wang M, Harrington L, Hwang S, Hidalgo-Reyes Y, Sontheimer EJ, Doudna J, Davidson AR, Moraes TF, Wang Y, Maxwell KL. Inhibition of CRISPR-Cas9 ribonucleoprotein complex assembly by anti-CRISPR AcrIIC2. Nat Commun. 2019;10(1):2806. Epub 2019/06/28. doi: 10.1038/s41467-019-10577-3. PubMed PMID: 31243272; PMCID: PMC6594998.
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Topal S, Vasseur P, Radman-Livaja M, Peterson CL. Distinct transcriptional roles for Histone H3-K56 acetylation during the cell cycle in Yeast. Nat Commun. 2019;10(1):4372. Epub 2019/09/29. doi: 10.1038/s41467-019-12400-5. PubMed PMID: 31558720; PMCID: PMC6763489.
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Vasquez-Rifo A, Veksler-Lublinsky I, Cheng Z, Ausubel FM, Ambros V. The Pseudomonas aeruginosa accessory genome elements influence virulence towards Caenorhabditis elegans. Genome Biol. 2019;20(1):270. Epub 2019/12/12. doi: 10.1186/s13059-019-1890-1. PubMed PMID: 31823826; PMCID: PMC6902481. https://www.ncbi.nlm.nih.gov/pubmed/31823826   

Vertii A, Ou J, Yu J, Yan A, Pages H, Liu H, Zhu LJ, Kaufman PD. Two contrasting classes of nucleolus-associated domains in mouse fibroblast heterochromatin. Genome Res. 2019;29(8):1235-49. Epub 2019/06/16. doi: 10.1101/gr.247072.118. PubMed PMID: 31201210; PMCID: PMC6673712.
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