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UMMS PacBio Core Enterprise logo

    The PacBio Core Enterprise operates a Pacific Biosciences Sequel II Instrument with the newest version of the run chemistry (read lengths over 50kb) and SMRT Link data analysis. The service includes (as a package deal): library construction from submitted DNA or RNA, sequencing of one SMRTcell, and quality filtering/run metrics. Multiplexing is available using either internal PacBio Barcoded Universal Primers (for amplicon libraries) or PacBio Barcoded Adapters. Additional bioinformatics options are available for a fee. Please contact us about your project. We'd love to work with you!

The PBCE is closely united with the Deep Sequencing and Molecular Biology Cores, and all three Cores work together to provide streamlined sample analysis services. Click on the logos at the left to visit the websites of the other facilities.

Pricing, Support, and Other Details
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For a copy of the service ticket, sequencing pricing list, details on specific services, scheduling, or a quote for services, please email us here. Information about grant support letters can be found on our Grant Support page.

Join Email List or Send a Suggestion
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Contact us if you would like to be added to our PacBio email list for news and service updates.

We try to keep our Resources section relevant. If you have a protocol or publication that you found useful, or a request for something you think would be beneficial on the website, please email us at PacBio@umassmed.edu.

Other Useful Information
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Drop-off locations:
Samples can be left in the labeled fridges at these locations
for 11:00 AM pickup each business day:
Biotech2 outside Suite 207
LRB 6th floor mailroom
AS8-2046 on top of the filing cabinet
We are also available by appointment if you need to visit with us.
Our shipping address for off-campus customers is
Rose-Gordon Bldg. Rm. 141, 222 Maple Ave, Shrewsbury, MA, 01545.

Pricing and Payment Policy
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Please email PacBio@umassmed.edu to get a quote for your desired services.

Processing and analyzing a sample requires time and reagents. Payment for these services is the responsibility of the user submitting the sample and should be rendered in a timely fashion. In the event of a reagent or equipment failure, the samples will be rerun at the next possible opportunity at no additional charge.

Clients withdrawing samples prior to the analysis run will be charged a fee to recover QC assay costs. For the return of archived post-analysis samples, clients will be charged a delivery fee per sample.

Inclement Weather Policy
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In case of extreme and/or inconvenient weather, the machines will still be running but we may not be here for sample login, pickup, or delivery. Please email us to arrange drop-off if the weather is questionable. The PBCE, DSCL, & MBCL are closed when UMassMed is on "inclement weather alert".

UMMS Deep Sequencing Core logo linking to website

UMMS Molecular Biology Core Labs logo linking to website