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Michael J. Lee, PhD

Research Focus - Cancer Systems Pharmacology

  • Computational design of anticancer drug combinations
  • Use of genetic screening to understand mechanisms of regulated cell death
  • Examination of the mechanisms of interaction between apoptotic and non-apoptotic death
  • Characterization of the mechanisms of drug resistance
  • Modeling of signaling pathway circuitry in the DNA damage response

Representative Publication

Landry BD, Leete T, Richards R, et al. Tumor-stroma interactions differentially alter drug sensitivity based on the origin of stromal cells. Mol Syst Biol. 2018;14(8):e8322.

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