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Terence R. Flotte, MD

Celia and Isaac Haidak Professor, Dean of the T.H. Chan School of Medicine
Provost and Executive Deputy Chancellor
"This is an exciting time to be pursuing a career in medicine and applying to the UMass Chan Medical School."

 

About the dean 

Terence R. Flotte, MD

Terence R. Flotte, MD, is provost, dean and executive deputy chancellor of UMass Chan Medical School, the only public medical school in Massachusetts. Since joining UMass Chan in 2007, Dr. Flotte has forged a path of unprecedented growth and achievement for the research, education and academic missions of the campus.

An internationally known scientist, Flotte has conducted research on cutting edge molecular therapeutics that led to the first successful gene transfer with adeno-associated virus (AAV) in animals and the first ever human trial of an AAV. He also led the first human recombinant AAV trials in alpha-1 antitrypsin deficiency and Tay-Sachs disease, with the latter showing promising clinical benefits.

He is the author of more than 280 scholarly papers and his research has been funded by the National Institutes of Health and the Alpha One Foundation. Since 2015, Flotte has also been editor-in-chief of gene therapy’s oldest journal family, Human Gene Therapy. 

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  • Massachusetts Secretary of Economic Development Yvonne Hao announced a $555,000 grant from the Massachusetts Technology Collaborative to UMass Chan on April 10, to be matched with $137,000 private investment, for the establishment of the Health AI Assurance Laboratory, in partnership with MITRE and the Coalition for Health AI. Pictured at the announcement, from left to right: Francis Campion, MITRE; Ozgur Eris, MITRE; Brian Anderson, CHAI; Carolyn Kirk, MassTech; Patrick Larkin, MassTech; Secretary Yvonne Hao; Terence R. Flotte, UMass Chan; Michael F. Collins, UMass Chan; Senator Robyn Kennedy; Doug Robbins, MITRE; Melissa Fischer, UMass Chan; Miles Thompson, MITRE; David McManus, UMass Chan.

    UMass Chan and MITRE launch Health AI Assurance Laboratory with MassTech grant

    UMass Chan Medical School and MITRE, operator of federally funded research and development centers, announced the establishment of the Health AI Assurance Laboratory, a collaborative initiative to advance health artificial intelligence in the public interest. The initiative is at the forefront of efforts in the United States, and the first in Massachusetts, to ensure AI technology in health care is safe and effective for everyone using it.

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  • At Second Look Day, presence and intentionality connect students to UMass Chan

    At Second Look Day, presence and intentionality connect students to UMass Chan

    Second Look Day introduced accepted medical students to the T.H. Chan School of Medicine and included programming from the Diversity and Inclusion office.

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  • UMass Chan and Lahey partner on new clinical and quantitative research science hub

    UMass Chan and Lahey partner on new clinical and quantitative research science hub

    UMass Chan Medical School and Lahey Hospital & Medical Center, part of the Beth Israel Lahey Health system, have signed a research affiliation agreement to create a new quantitative science research hub to improve health outcomes and disparities through population health, digital medicine and health systems science.  

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  • Match Day 2024 at UMass Chan: ‘Excited about the future . . . and the patients I will serve’

    Match Day 2024 at UMass Chan: ‘Excited about the future . . . and the patients I will serve’

    Members of the T.H. Chan School of Medicine Class of 2024—the largest in school history at 167—celebrated Match Day at UMass Chan Medical School on Friday, March 15, with hundreds of friends, relatives and faculty cheering them on.  

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  • Dean Flotte testifies at congressional hearing in support of gene therapy development

    Dean Flotte testifies at congressional hearing in support of gene therapy development

    Dean Flotte testified in support of policies that would encourage and accelerate gene therapy for rare diseases, in a Feb. 29 hearing before the House Committee on Energy and Commerce’s Subcommittee on Health.

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  • New issue of @umasschan magazine highlights stories of gene therapy ‘heroes’

    New issue of @umasschan magazine highlights stories of gene therapy ‘heroes’

    The cover story for the winter 2023-24 issue of @umasschan magazine highlights how the families of children with genetic disorders inspire gene therapy research and how UMass Chan is streamlining the pathway from bench research to clinical trials for new treatments.

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  • Top story: Family connects with researchers behind Canavan gene therapy

    Top story: Family connects with researchers behind Canavan gene therapy

    Top story: Boston toddler Noa Greenwood, who was one of the first to receive an investigational gene therapy for Canavan disease developed at UMass Chan Medical School, delivered a very special “thank you” to the research team in a visit with her parents earlier this year.

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  • Top story: UMass Chan best in New England for primary care education

    Top story: UMass Chan best in New England for primary care education

    Top story: The T.H. Chan School of Medicine at UMass Chan Medical School is best in New England and in the top 10 percent nationwide for primary care education according to the U.S News & World Report 2023-2024 Best Graduate Schools rankings.

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  • Top story: UMass Chan-Lahey regional medical school campus approved by LCME

    Top story: UMass Chan-Lahey regional medical school campus approved by LCME

    UMass Chan Medical School and Lahey Hospital & Medical Center, part of Beth Israel Lahey Health, have received approval from the Liaison Committee on Medical Education to establish a new regional medical school campus in Burlington.

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  • UMass Chan Medical School joins ARPA-H Investor Catalyst Hub and Spoke Consortium

    UMass Chan Medical School joins ARPA-H Investor Catalyst Hub and Spoke Consortium

    UMass Chan Medical School joins ARPA-H Investor Catalyst Hub and Spoke Consortium

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