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Torres Lab Publications

Hwang S, Cavaliere P, Li R, Zhu LJ, Dephoure N, Torres EM. Consequences of aneuploidy in human fibroblasts with trisomy 21. Proc Natl Acad Sci U S A2021 Feb 9;118(6). PubMed PMID: 33526671.

Hwang S, Williams JF, Kneissig M, Lioudyno M, Rivera I, Helguera P, Busciglio J, Storchova Z, King MC, Torres EM. (2019) Suppressing Aneuploidy-Associated Phenotypes Improves the Fitness of Trisomy 21 Cells. Cell Reports. Nov 19 2019. PMID:31747614

Hwang S, Gustafsson HT, O’Sullivan C, Bisceglia G, Huang X,  Klose C, Schevchenko A, Dickson RC, Cavaliere P,Dephoure N,  Torres EM. (2017). Serine-dependent Sphingolipid Synthesis is a metabolic liability of aneuploid cells. Cell Reports. PMID: 29281829

Zaytouni T, Tsai PY, Hitchcock DS, DuBois CD, Freinkman E, Lin L, Morales-Oyarvide V, Lenehan PJ, Wolpin BM, Mino-Kenudson M, Torres EM, Stylopoulos N, Clish CB, Kalaany NY. (2017). Critical role for arginase 2 in obesity-associated pancreatic cancer. Nature Communications. PMID: 28808255 

Wang F, Shin J, Shea JM, Yu J, Bošković A, Byron M, Zhu X, Shalek AK, Regev A, Lawrence JB, Torres EM, Zhu LJ, Rando OJ, Bach I.(2016) Regulation of X-linked gene expression during early mouse development by Rlim. Elife. PMID: 27642011

Torres EM, Springer M, Amon A. (2016). No current evidence for widespread dosage compensation in S. cerevisiae. Elife. PMID: 26949255

Torres E. (2015). Yeast as Models of Mitotic Fidelity. Recent Results Cancer Res. 200:143-64. PMID: 26376876

Dephoure N, Hwang S, O'Sullivan C, Dodgson SE, Gygi SP, Amon A, Torres EM. (2014). Quantitative proteomic analysis reveals posttranslational responses to aneuploidy in yeast. Elife. Jul 29;3:e03023. PMID: 2573701

Sheltzer, J.M., Torres, E.M., Dunham, M.J., and Amon, A. (2012). Transcriptional consequences of aneuploidy. Proceedings of the National Academy of Sciences 109(31),12644-9. PMID: 22802626

Torres, E.M.,Williams, B.R., Tang, Y.C., and Amon, A. (2011). Thoughts on aneuploidy. Cold Spring Harbor Symposia on Quantitative Biology 75, 445-451. PMID: 21289044 

Torres, E.M.,Dephoure, N., Panneerselvam, A., Tucker, C.M., Whittaker, C.A., Gygi, S.P., Dunham, M.J., and Amon, A. (2010). Identification of aneuploidy-tolerating mutations. Cell 143, 71-83. PMID: 20850176

Torres, E.M.,Williams, B.R., and Amon, A. (2008). Aneuploidy: cells losing their balance. Genetics 179, 737-746. PMID: 18558649

Torres, E.M.,Sokolsky, T., Tucker, C.M., Chan, L.Y., Boselli, M., Dunham, M.J., and Amon, A. (2007). Effects of aneuploidy on cellular physiology and cell division in haploid yeast. Science 317, 916-924. PMID:17702937

Torres, E.,and Rosen, M.K. (2006). Protein-tyrosine kinase and GTPase signals cooperate to phosphorylate and activate Wiskott-Aldrich syndrome protein (WASP)/neuronal WASP. Journal of Biological Chemistry 281, 3513-3520. PMID: 16293614

Panchal, S.C., Kaiser, D.A., Torres, E., Pollard, T.D., and Rosen, M.K. (2003). A conserved amphipathic helix in WASP/Scar proteins is essential for activation of Arp2/3 complex. Nature Structural Biology 10, 591-598.  PMID: 12872157

Torres, E., and Rosen, M.K. (2003). Contingent phosphorylation/dephosphorylation provides a mechanism of molecular memory in WASP. Molecular Cell 11, 1215-1227. PMID: 12769846