Principal Investigator

John E. Landers, Ph.D. 

Associate Professor 
UMass Chan Medical School 
Department of Neurology 
Worcester MA 01605 
Office: LRB604 
Telephone: 508-856-6221 
Email: john.landers@umassmed.edu 

Key Publications 

Kwiatkowski T.J. et al. Mutations in the FUS/TLS Gene on Chromosome 16 Cause Familial Amyotrophic Lateral Sclerosis. Science 2009; 323:1205-8. 

Landers J.E. et al. Genetic Variants in Kinesin-Associated Protein Gene KIFAP3 Modify Survival in Sporadic Amyotrophic Lateral Sclerosis. Proc. Natl. Acad. Sci. USA. 2009; 106:9004-9. 
Ticozzi N. et al. Analysis of FUS Gene Mutation in Familial Amyotrophic Lateral Sclerosis within an Italian cohort. Neurology 2009; 73:1180-5. 
van Es M.A. et al. Genome-wide association study identifies UNC13A and 9p21.2 as susceptibility loci for sporadic Amyotrophic Lateral Sclerosis. Nature Genet. 2009; 41:1083-7. 
Ticozzi N. et al. Mutational analysis of TARDBP in neurodegenerative diseases. Neurobiol Aging. 2011; 32:2096-9. 
Ticozzi N. et al. Paraoxonase gene mutations in amyotrophic lateral sclerosis. Ann Neurol. 2010; 68:102-7. 
Blauw H.M. et al. A large genome scan for rare CNVs in amyotrophic lateral sclerosis. Hum Mol Genet. 2010; 19:4091-9. 
Ticozzi N. et al. Mutational analysis reveals the FUS homolog TAF15 as a candidate gene for familial amyotrophic lateral sclerosis. Am. J. Med. Gen. Part B: Neuropsychiatric Genetics. 2011; 156:285-90. 
van Es M.A. et al. Angiogenin mutations in Parkinson’s disease and amyotrophic lateral sclerosis. Ann Neurol. In Press.