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Department of Biochemistry and Molecular Pharmacology

Research is core to the mission of the Department of Medicine. The Department has an exceptional foundation in basic research and is nationally recognized for its success in building interdisciplinary teams capable of supporting high-quality clinical research. Department investigators across several divisions have created outstanding research programs spanning basic, translational and clinical research. Investigators are supported by department-based initiatives, such as the Clinical Research Core, which expand investigators’ capabilities, enhance collaboration, and support rapid discovery and translation. Additionally,  interdepartmental and interdisciplinary programs such as the Program in Innate Immunity and Program in Digital Medicine also contribute to the ingenuity and vitality of the Department's investigators and research labs. These programs offer investigators unique resources and opportunities for collaboration within their divisions and the department, as well as interdepartmentally at UMass Chan Medical School.

The Department of Medicine is committed to providing a diverse, equitable, and inclusive environment for our faculty, postdocs, students, and staff. We oppose discrimination in all forms and strive to educate ourselves about systemic issues by actively engaging in an ongoing dialogue and learning from all members of the program as well as the broader community. We believe that by doing so, we not only strive to provide an environment that is welcoming to all but that also enriches our personal and professional perspectives and approaches to our research and clinical care.

The Department of Biochemistry and Molecular Pharmacology strives to bring a molecular perspective to problems in biology and medicine. With a mission to advance our knowledge in BiophysicsCell and Developmental BiologyComputational Biology, Chemical BiologyDevelopmental BiologyDNA/RNA and EpigeneticsHuman Disease and TherapeuticsNeurobiologyMembrane Biology and Structural Biology, we strive to translate discoveries in basic science to clinical applications in our hospital. 

Research topics include:  mechanisms of protein folding, protein dynamics and assembly, bio-organic chemistry, RNA biology, structural biology, molecular modeling, molecular pharmacology, mechanisms of epigenetic inheritance, drug discovery, developmental biology, DNA repair and recombination, protein translocation mechanisms, gene expression, neuroscience and membrane biology.  Collaborations with colleagues in other basic science and clinical departments enrich the possibilities for translating discoveries in basic science to clinical applications in our hospital.  And the recently initiated development of companion programs in RNA Therapeutics, Stem Cell Biology and Gene Therapy portend new opportunities in translational research for our faculty and students.

Please access and learn more about our open positions that are posted to the right of the page. Also, please access the following laboratory websites where positions are available: