Metallic Implant Surface Modifications
Strategies to reduce periprosthetic infections and enhance implant osteointegration
Jordan D. Skelly, Feiyang Chen, Shing-Yun Chang, Rewati R. Ujjwal, Ananta Ghimire, David C. Ayers and Jie Song. Tuning On-demand Releases of Vancomycin Covalently Tethered to Implant Coatings through the Chemical Modification of a Micrococcal-Nuclease-Sensitive Oligonucleotide Linker. ACS Appl Mater Interfaces 2023, 10.1021/acsami.3c05881. View Publication
Ananta Ghimire and Jie Song. Anti-periprosthetic infection strategies: from implant surface topographical engineering to smart drug-releasing coatings. ACS Appl Mater Interfaces. 2021, 13(18):20921–20937. View Publication.
Ben Zhang, Jordan D. Skelly, Benjamin Braun, David C. Ayers and Jie Song. Surface-grafted zwitterionic polymers improve the efficacy of a single antibiotic injection in suppressing Staphylococcus aureus periprosthetic infections ACS Appl Bio Mater 2020, 3(9), 5896-5904. View Publication
Ananta Ghimire, Jordan D. Skelly and Jie Song. Micrococcal-nuclease-triggered on-demand release of vancomycin from Intramedullary implant coating eradicates Staphylococcus aureus infection in mouse femoral canals. ACS Central Science 2019, Dec 10; 5(12): 1929–1936. View Publication