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Current Members

Celia Schiffer

Celia A. Schiffer, PhD

Principal Investigator
Gladys Smith Martin Chair in Oncology
Director Institute for Drug Resistance (IDR)

LRB 828
Tel: 508-856-8008
 

Theme: Drug Resistance
Diseases: HIV; HCV; Cancer; Influenza; Dengue
Proteins: HIV-1 protease; HCV NS3/4A protease; APOBEC3's; Influenza neuraminindase; Influenza hemagglutinin; Dengue NS2B/NS3 protease
Research Technique: Everything

IDR Website

Akbar Ali, PhD

Akbar Ali, PhD

Associate Professor

Tel: 508-856-8873
 

Theme: Drug Resistance
Diseases: HIV; HCV; Dengue; Cancer
Proteins: HIV-1 protease; HCV NS3/4A protease; Dengue NS2B/NS3; APOBEC3's
Research Technique: Organic Chemistry

Mohan Somasundaran, PhD

Mohan Somasundaran, PhD

Associate Professor, Virologist

Tel: 508-856-4151
 

Theme: Drug Resistance
Diseases: HIV; Cancer
Proteins: APOBEC3's; HIV-1 protease
Research Technique: Molecular Virology

Nese Kurt Yilmaz, PhD

Nese Kurt Yilmaz, PhD

Associate Professor

Tel: 508-856-1867
 

Theme: Drug Resistance
Diseases: HIV; HCV; Cancer; Influenza; Dengue
Proteins: HIV-1 protease; HCV NS3/4A protease; APOBEC3's; Influenza neuraminidase; Dengue NS2B/NS3
Research Techniques: Enzyme Inhibition; Structural Analysis; Lab Managing

Ellen Nalivaika

Ellen Nalivaika

Senior Research Associate

 

Theme: Drug Resistance
Diseases: HIV; HCV; Cancer; Influenza; Dengue
Proteins: HIV-1 protease; HCV NS3/4A protease; Influenza neuraminidase; Dengue NS2B/NS3
Research Techniques: Lab Managing; Protein Expression; Protein Crystallization; Enzyme Inhibition

Jeong Min Lee

Jeong Min Lee, PhD

Postdoctoral Associate

 

Nageswara Rao Desaboini

Nageswara Rao Desaboini, PhD

Postdoctoral Associate

 

Theme: Drug Resistance
Diseases: HIV; Dengue
Proteins: HIV-1 protease; Dengue
Research Techniques: Organic Chemistry

Jennifer Timm

Jennifer Timm, PhD

Postdoctoral Associate

 

Theme: Drug Resistance
Disease: HCV
Protein: NS3/4A (GT1-6)
Research Techniques: Protein expression; Purification; Crystallization; Structural Analysis

Shurong Hou

Shurong Hou

PhD Student

 

Theme: Innate Immunity
Diseases: Cancer; HIV
Protein: APOBEC3's
Research Techniques: Molecular Dynamics; Protein Expression; Structure Based Drug Design

Anne Jecrois

Anne Jecrois

PhD Student / joint with Royer Lab

 

Theme: Signal Transduction
Disease: Cancer
Protein: IRFs
Research Techniques: Protein Expression; Protein Crystallization

Florian Leidner

Florian Leidner

Research Associate

 

Theme: Drug Resistance
Disease: HIV
Protein: HIV-1 protease
Research Technique: Molecular Dynamics

Gordon Lockbaum

Gordon Lockbaum

PhD Student

 

Theme: Drug Resistance
Disease: HIV
Protein: HIV-1 Protease
Research Techniques: Protein expression, Enzymology, Protein Crystallography, Structural Analysis

Heather Loring

Heather Loring

PhD Student / joint with Thompson Lab

 

Theme: Drug Design
Diseases: Cancer
Proteins: SARM1
Research Techniques: Structure Based Drug Design, Enzymology, Protein Expression, Crystallography

Jacqueto Zephyr

Jacqueto Zephyr

PhD Student

 

Theme: Drug Design, Drug Resistance
Diseases: DENV, ZIKV, HCV
Proteins: DENV and ZIKV NS2B-NS3 proteases, and HCV NS3/4A protease
Research Techniques: Organic chemistry, Structure Based Drug Design, Enzymology, Protein Expression, Crystallography

Mina Henes

Mina Henes

Intern

Theme: Drug Resistance
Diseases: HIV, HTLV, HCV
Proteins: HIV-1 and HTLV-1 proteases, and HCV NS3/4A protease
Research Techniques: Protein expression, Enzymology, Molecular Dynamics, Structure analysis

 

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