Campus Alert: Find the latest UMMS campus news and resources at

Search Close Search
Search Close Search
Page Menu

Research Focus

Protein structure and dynamics with biophysical and computational methods

Research Focus.png

Proteins fold into specific three-dimensional structures and interact with other proteins and ligands. Elucidation of these structures at the atomic level, as well as interactions with other molecules and conformational flexibility, is essential for understanding biological function. Using a synergistic combination of experimental and computational techniques enables fundamental insights into molecular recognition events involving protein-protein and protein-ligand interactions. Our research aims to understand these molecular recognition events for proteins with key roles in viral infections, with a focus on inhibitor binding and drug resistance.

Read More


Total: 1 results
  • Drug Design Strategies to Avoid Resistance in Direct-Acting Antivirals and Beyond

    Thursday, January 07, 2021
    Author(s): Ashley N Matthew,Florian Leidner,Gordon J Lockbaum,Mina Henes,Jacqueto Zephyr,Shurong Hou,Desaboini Nageswara Rao,Jennifer Timm,Linah N Rusere,Debra A Ragland,Janet L Paulsen,Kristina Prachanronarong,Djade I Soumana,Ellen A Nalivaika,Nese Kurt Yilmaz,Akbar Ali,Celia A Schiffer
    Source: Chemical reviews
All Publications


Follow our research, stay in touch – join the lab! 

Contact Us


Campus Map (pdf)

508-856-1867 (office)


Mailing Address:
University of Massachusetts Medical School
Attn: Nese Kurt Yilmaz, PhD
Associate Professor
Department of Biochemistry & Molecular Pharmacology
364 Plantation Street, LRB 970-J
Worcester MA, 01605-2324

Join Us

Undergraduates interested in pursuing a PhD at UMass Medical School should apply directly to the Graduate School of Biomedical Sciences Program.