2018 RESEARCH
- Archives -RNAi therapy mitigates preeclampsia symptoms in UMass Medical School study
A new study by Anastasia Khvorova, PhD, and Melissa Moore, PhD, at UMass Medical School and colleagues at Beth Israel Deaconess Medical Center and Western Sydney University, suggests that RNA interference therapy could be a potential strategy for the treatment of preeclampsia.
M2D2 receives $7.9M NIH grant for new center to assist medical-device entrepreneurs
The Massachusetts Medical Device Development Center, a joint partnership between UMass Lowell and UMass Medical School, will establish a new center to assist inventors pioneering promising new point-of-care devices and technologies for patients, thanks to a new $7.9 million grant for the National Institutes of Health.
Blu Genes Foundation gives UMMS $1.4M to bring Tay-Sachs gene therapy to clinical trial
The Toronto-based Blu Genes Foundation, which is dedicated to developing gene therapies for rare disease, has given $1.4 million to UMass Medical School to advance a Phase I/II clinical trial for Tay-Sachs. Miguel Sena-Esteves, PhD, Terence Flotte, MD, Heather Gray-Edwards, PhD, DVM, and colleagues at Auburn University are leading the research.
David Ayers, Patricia Franklin highlight value of patient-reported outcomes registries in NEJM Catalyst
A new analysis by Patricia Franklin, MD, MBA, MPH, and David Ayers, MD, published by NEJM Catalyst, explains why patient outcome registries such as the Function and Outcomes Research for Comparative Effectiveness in Total Joint Replacement are essential to informing health policy and treatment decisions.
Robert Brown Jr. and Jonathan Watts honored by Angel Fund for ALS
Jonathan K. Watts, PhD, and Robert H. Brown Jr., DPhil, MD, were recognized at the annual Angel Fund for ALS Gala on Oct. 27. The organization is a nonprofit charity dedicated to supporting Dr. Brown’s research.
UMass Medical School scientists safely deliver RNAi-based gene therapy for ALS in animal model
A gene therapy delivered to motor neurons was able to silence SOD1 protein, mutations of which are linked to ALS, without causing any adverse effects, according to a new study published in Science Translational Medicine, by Christian Mueller, PhD, and Robert H. Brown Jr., DPhil, MD.
Better strategies to ID people at risk for opioid-related overdose deaths needed, study suggests
A new study by Gerardo Gonzalez, MD, examines how health care systems may be able to help prevent opioid-related overdose deaths. The findings are published in Psychiatric Services.
Silvia Corvera, Michael Czech receive $2.5M grant to advance potential therapy for type 2 diabetes
Silvia Corvera, MD, and Michael Czech, PhD, are investigating whether technologies developed in their labs will harness beige fat’s ability to burn energy and accelerate metabolism in order to improve the body’s response to sugar and lower blood glucose levels.
Postdoc Tessa Simone explores role of immune cells in cancer
Tessa Simone, PhD, a postdoc in the lab of Michael R. Green, MD, PhD, is focused on identifying ways to teach the immune system to attack cancerous tumors without harming healthy tissue.
UMMS scientists featured in special edition of Small Methods journal
Multidisciplinary research in chemical biology, life sciences and medicine at UMass Medical School is featured in a special issue of the journal Small Methods. The collection of papers spans a wide disciplinary range that includes biomedical engineering/materials science, frontiers in optical microscopy and organic synthesis, as well as nanoparticle technology and emerging CRISPR‐based genomic sciences.
