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Anastasia Khvorova headshot

Anastasia Khvorova, PhD


Professor, RNA Therapeutics Institute and Program in Molecular Medicine


Focus:
Medicinal chemistry of oligonucleotides; mechanism of small RNA trafficking; expanding chemical diversity of oligonucleotides for treatment of neurodegenerative disorders


Education:
Russian Academy of Sciences, Moscow, Russia

 Annabelle Biscans

Annabelle Biscans, PhD


Postdoctoral Associate, RNA Therapeutics Institute


Focus: Nucelic acid and oligonucleotide chemistries; development, optimization, and characterization of novel chemically modified oligonucleotides to enhance efficacy and biodistribution

Education: University of Montpellier, France

Andrew Coles

Andrew H Coles, PhD


Postdoctoral Associate, RNA Therapeutics Institute


Focus:
Oligonucleotide pharmacology; managing laboratory animal protocols; development of high-throughput (HTS) animal models for evaluation of oligonucleotide pharmokinetic and pharmodynamic (PK/PD) behavior


Education:
University of Massachusetts Medical School, Worcester, MA

 Marie Didiot

Marie-Cécile Didiot, PhD


Postdoctoral Associate, RNA Therapeutics Institute


Focus:
Oligonucleotide cell biology; identification of cellular pathways implicated in small RNA trafficking; exosomes as vehicles for oligonucleotide delivery for treatment of Huntington's disease


Education:
Institut de gènétique et de biologie molécular et cellulaire, University of Strasbourg, France

Bruno Godinho

Bruno Miguel da Cruz Godinho, PhD


Postdoctoral Associate, RNA Therapeutics Institute


Focus:
Oligonucleotide pharmacology; oligonucleotide engineering for improved tissue distribution and crossing the blood-brain barrier


Education:
University College Cork, Ireland

Matthew Hassler

Matthew R Hassler, PhD


Postdoctoral Associate, RNA Therapeutics Institute


Focus:
Oligonucleotide chemistry; managing Nucleic Acid Chemistry Core; novel platforms for expanding chemical diversity of oligonucleotides


Education:
McGill University, Montréal, Québec, Canada

 Maire Osborn

Maire F Osborn, PhD


Postdoctoral Associate, RNA Therapeutics Institute


Focus:
Oligonucleotide chemistry and biochemistry; modulation of oligonucleotide tissue distribution, efficacy, and toxicity through chemical engineering; novel siRNA conjugates for treatment of neurodegenerative disorders such as Huntington's disease


Education:
University of Oregon, Eugene, OR

Loic Roux

Loïc Roux, PhD


Postdoctoral Associate, RNA Therapeutics Institute


Focus:
Nucleic acid chemistry; expanding chemical diversity of oligonucleotides; development of novel chemical modalities for optimization of oligonucleotide intracellular localization and targeted delivery


Education:
Aix-Marseille University, France

Anton Turanov

Anton A Turanov, PhD


Postdoctoral Associate, RNA Therapeutics Institute


Focus:
Oligonucleotide cell biology and pharmacology; development and optimization of oligonucleotide chemical composition for systemic delivery to placenta; RNAi-based novel approaches for treatment of preeclampsia


Education:
University of Nebraska, Lincoln, NE

Dimas Echeverria

Dimas Echeverria Moreno


Research Associate, RNA Therapeutics Institute


Focus:
Nucleic Acid Chemistry Core; oligonucleotide synthesis, purification, and quality control


Education:
Universidad del Valle, Cali, Colombia

Julia Alterman

Julia F Alterman, MLA


PhD Student, Graduate School of Biomedical Sciences


Focus:
Expanding chemical diversity of oligonucleotides for treatment of neurodegenerative disorders such as Huntington's disease


Education:
Harvard University, Cambridge, MA

 

Sarah Davis


PhD Student, Graduate School of Biomedical Sciences


Focus:


Education: Connecticut College, New London, CT

 

Chantal M Ferguson


MD/PhD Student, School of Medicine and Graduate School of Biomedical Sciences


Focus:


Education: Wesleyan University, Middletown, CT

 James Gilbert

James Gilbert


PhD Student, Graduate School of Biomedical Sciences


Focus:
Development of novel oligonucleotide approaches for treatment of amyotrophic lateral sclerosis (ALS)


Education:
University of Bath, England

Reka Haraszti

Reka A Haraszti, MD


PhD Student, Graduate School of Biomedical Sciences


Focus:
Understanding extracellular vesicle (EV) trafficking; development of artifical exosomes as vehicles for oligonucleotide central nervous system (CNS) delivery


Education:
Semmelweis University Medical School, Budapest, Hungary

Havisha Karnam

Havisha Karnam


MD/PhD Student, School of Medicine and Graduate School of Biomedical Sciences


Focus:
Development of novel oligonucleotide chemistries for dorsal root ganglia (DRG) delivery; novel oligonucleotide approaches for treatment of heridtary neuropathy (HSAN1)


Education:
Dartmouth College, Hanover, NH

Socheata Ly

Socheata Ly


PhD Student, Graduate School of Biomedical Sciences


Focus:
Defining trafficking pathways utilized by different classes of oligonucleotides using high resolution microscopy and quantitative mass spectrometry


Education:
Clark University, Worcester, MA

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