Page Menu

Alkema Lab Publications

Publications from 2019

Diapause induces functional axonal regeneration after necrotic insult in C. elegans, Mauricio Caneo, Victoria Julian, Alexandra B. Byrne, Mark J. Alkema, and Andrea Calixto  PDF

Co-option of neurotransmitter signaling for inter-organismal communication in C. elegans, Christopher D. Chute, Elizabeth M. DiLoreto, Ying K. Zhang, Douglas K. Reilly, Diego Rayes, Veronica L. Coyle, Hee June Choi, Mark J. Alkema, Frank C. Schroeder, and Jagan Srinivasan  PDF

Gain-of-function mutations in the UNC-2/CaV2alpha channel lead to excitation-dominant synaptic transmission in C. elegans, Yung-Chi Huang, Jennifer K. Pirri, Diego Rayes, Shangbang Gao, Ben Mulcahy, Jeff Grant, Yasunori Saheki, Michael M. Francis, Mei Zhen, and Mark J. Alkema PDF

Publications from 2018

Excitatory motor neurons are local oscillators for backward locomotion, Shangbang Gao, Sihui Asuka Guan, Anthony D. Fouad, Jun Meng, Taizo Kawano, Yung-Chi Huang, Yi Li, Salvador Alcaire, Wesley Hung, Yangning Lu, Yingchuan Billy Qi, Yishi Jin, Mark J. Alkema, Christopher Fang-Yen, and Mei Zhen  PDF

Neurexin directs partner-specific synaptic connectivity in C. elegans, Alison Philbrook, Shankar Ramachandran, Christopher M. Lambert, Devyn Oliver, Jeremy Florman, Mark J. Alkema, Michele Lemons, and Michael M. Francis  PDF

Publications from 2017

Excitatory Motor Neurons are Local Central Pattern Generators in an Anatomically Compressed Motor Circuit for Reverse Locomotion, Shangbang Gao, Sihui Asuka Guan, Anthony D. Fouad, Jun Meng, Yung-Chi Huang, Yi Li, Salvador Alcaire, Wesley Hung, Taizo Kawano, Yangning Lu, Yingchuan Billy Qi, Yishi Jin, Mark J. Alkema, Christopher Fang-Yen, and Mei Zhen  PDF

Behavioral and Functional Analysis of a Calcium Channelopathy in Caenorhaditis elegans, Yung-Chi Huang  PDF

Selenoprotein T is required for pathogenic bacteria avoidance in Caenorhabditis elegans, Laura Romanelli-Cedrez, Ines Carrera, Lucia Otero, Antonio Miranda-Vizuete, Marco Mariotti, Mark J. Alkema, and Gustavo Salinas  Link

Publications from 2016

The Genetic Basis of Natural Variation in Caenorhabditis elegans Telomere Length, Daniel E. Cook, Stefan Zdraljevic, Robyn E. Tanny, Beomseok Seo, David D. Riccardi, Luke M. Noble, Matthew V. Rockman, Mark J. Alkema, Christian Braendle, Jan E. Kammenga, John Wang, Leonid Kruglyak, Marie-Anne Felix, Junho Lee, and Erik C. Andersen  PDF

The genetic basis of natural variation in C. elegans telomere length, Daniel E. Cook, Stefan Zdraljevic, Robyn E. Tanny, Beomseok Seo, David Riccardi, Luke M. Noble, Matthew V. Rockman, Mark J. Alkema, Christian Braendle, Jan Kammenga, John Wang, Leonid Kruglyak, Marie-Anne Felix, Junho Lee, and Erik Andersen  PDF

Imprinting: When Early Life Memories Make Food Smell Bad, Diego Rayes and Mark J. Alkema  Link

Pan-neuronal imaging in roaming Caenorhabditis elegans, Vivek Venkatachalam, Ni Ji, Xian Wang, Christopher M. Clark, James Kameron Mitchell, Mason Klein, Christopher J. Tabone, Jeremy Florman, Hongfei Ji, Joel Greenwood, Andrew D. Chisholm, Jagan Srinivasan, Mark J. Alkema, Mei Zhen, and Aravinthan D.T. Samuel  PDF

Publications from 2015

The NCA sodium leak channel is required for persistent motor circuit activity that sustains locomotion, Shangbang Gao, Lin Xie, Taizo Kawano, Michelle D. Po, Sihui Guan, Mei Zhen, Jennifer K. Pirri, and Mark J. Alkema  Link

Caenorhabditis elegans exhibit a coupling between the defecation motor program and directed locomotion, Stanislav Nagy, Yung-Chi Huang, Mark J. Alkema, and David Biron  PDF

Presynaptic BK channel localization is dependent on the hierarchical organization of alpha-catulin and dystrobrevin and fine-tuned by CaV2 calcium channels, Kelly H. Oh, Linu S. Abraham, Chandler Gegg, Christian Silvestri, Yung-Chi Huang, Mark J. Alkema, Jacob Furst, Daniela Raicu, and Hongkyun Kim  PDF

A Change in the Ion Selectivity of Ligand-Gated Ion Channels Provides a Mechanism to Switch Behavior, Jennifer K. Pirri, Diego Rayes, and Mark J. Alkema  PDF

Publications from 2014

A conserved dopamine-cholecystokinin signaling pathway shapes context-dependent Caenorhabditis elegans behavior, Raja Bhattacharya, Denis Touroutine, Belinda Barbagallo, Jason Climer, Christopher M. Lambert, Christopher M. Clark, Mark J. Alkema, and Michael M. Francis  PDF

Neural Orchestration of the C. elegans Escape Response: A Dissertation, Christopher M. Clark  PDF

Simultaneous optogenetic manipulation and calcium imaging in freely moving C. elegans, Frederick B. Shipley, Christopher M. Clark, Mark J. Alkema, and Andrew M. Leifer  PDF

Simultaneous optogenetic manipulation and calcium imaging in freely moving C. elegans, Frederick B. Shipley, Christopher M. Clark, Mark J. Alkema, and Andrew M. Leifer  PDF

Neuronal regeneration in C. elegans requires subcellular calcium release by ryanodine receptor channels and can be enhanced by optogenetic stimulation, Lin Sun, James Shay, Melissa McLoed, Kevin Roodhouse, Samuel H. Chung, Christopher M. Clark, Jennifer K. Pirri, Mark J. Alkema, and Christopher V. Gabel  Link

Publications from 2013

Monoaminergic orchestration of motor programs in a complex C. elegans behavior, Jamie L. Donnelly, Christopher M. Clark, Andrew M. Leifer, Jennifer K. Pirri, Marian Haburcak, Michael M. Francis, Aravinthan D. T. Samuel, and Mark J. Alkema  PDF

Anatomical basis of sun compass navigation II: The neuronal composition of the central complex of the monarch butterfly, Stanley Heinze, Jeremy Florman, Surainder Asokaraj, Basil el Jundi, and Steven M. Reppert  Link

Identification of distinct tyraminergic and octopaminergic neurons innervating the central complex of the desert locust, Schistocerca gregaria, Uwe Homberg, Jutta Seyfarth, Ulrike Binkle, Maria Monastirioti, and Mark J. Alkema  Link

The Role of Ion Channels in Coordinating Neural Circuit Activity in Caenorhabditis elegans: A Dissertation, Jennifer K. Pirri  PDF

Publications from 2012

The neuroethology of C. elegans escape, Jennifer K. Pirri and Mark J. Alkema  Link

Intercellular calcium signaling in a gap junction-coupled cell network establishes asymmetric neuronal fates in C. elegans, Jennifer A. Schumacher, Yi-Wen Hsieh, Shiuhwei Chen, Jennifer K. Pirri, Mark J. Alkema, Wen-hong Li, Chieh Chang, and Chiou-Fen Chuang  PDF

Publications from 2011

Tyraminergic G Protein-Coupled Receptors Modulate Locomotion and Navigational Behavior In C. Elegans: A Dissertation, Jamie L. Donnelly  PDF

Autoregulatory and paracrine control of synaptic and behavioral plasticity by octopaminergic signaling, Alex C. Koon, James A. Ashley, Romina Barria, Shamik DasGupta, Ruth Brain, Scott Waddell, Mark J. Alkema, and Vivian Budnik  Link

Optogenetic manipulation of neural activity in freely moving Caenorhabditis elegans, Andrew M. Leifer, Christopher Fang-Yen, Marc Gershow, Mark J. Alkema, and Aravinthan D. T. Samuel  Link

The C. elegans Touch Response Facilitates Escape From Predacious Fungi, Sean M. Maguire, Christopher M. Clark, Jennifer K. Pirri, John J. Nunnari, and Mark J. Alkema  Link

Publications from 2009

Oxygen sensation: into thick air, Mark J. Alkema  Link

A multiparameter network reveals extensive divergence between C. elegans bHLH transcription factors, Christian A. Grove, Federico De Masi, M. Inmaculada Barrasa, Daniel E. Newburger, Mark J. Alkema, Martha L. Bulyk, and Albertha J. M. Walhout  Link

A Tyramine-Gated Chloride Channel Coordinates Distinct Motor Programs of a Caenorhabditis elegans Escape Response, Jennifer K. Pirri, Adam D. McPherson, Jamie L. Donnelly, Michael M. Francis, and Mark J. Alkema  Link