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displaying 25 out of
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Gasdermin D deletion prevents liver injury and exacerbates extrahepatic damage in a murine model of alcohol-induced ACLF
March 26, 2025
Author(s):
Martí Ortega-Ribera,Yuan Zhuang,Veronika Brezani,Radhika S Joshi,Zsuzsanna Zsengeller,Prashanth Thevkar Nagesh,Aditi Datta,Gyongyi Szabo
Source:
eGastroenterology
Neutrophil extracellular traps (NETs) and NETosis in alcohol-associated diseases: A systematic review
March 17, 2025
Author(s):
Mohammed A S Khan,Byoung-Joon Song,Xin Wang,Shams Iqbal,Gyongyi Szabo,Sulie L Chang
Source:
Alcohol, clinical & experimental research
A single-nucleus and spatial transcriptomic atlas of the COVID-19 liver reveals topological, functional, and regenerative organ disruption in patients
March 15, 2025
Author(s):
Yered Pita-Juarez,Dimitra Karagkouni,Nikolaos Kalavros,Johannes C Melms,Sebastian Niezen,Toni M Delorey,Adam L Essene,Olga R Brook,Deepti Pant,Disha Skelton-Badlani,Pourya Naderi,Pinzhu Huang,Liuliu Pan,Tyler Hether,Tallulah S Andrews,Carly G K Ziegler,Jason Reeves,Andriy Myloserdnyy,Rachel Chen,Andy Nam,Stefan Phelan,Yan Liang,Mark Gregory,Shanshan He,Michael Patrick,Tushar Rane,Aster Wardhani,Amit Dipak Amin,Jana Biermann,Hanina Hibshoosh,Molly Veregge,Zachary Kramer,Christopher Jacobs,Yusuf Yalcin,Devan Phillips,Michal Slyper,Ayshwarya Subramanian,Orr Ashenberg,Zohar Bloom-Ackermann,Victoria M Tran,James Gomez,Alexander Sturm,Shuting Zhang,Stephen J Fleming,Sarah Warren,Joseph Beechem,Deborah Hung,Mehrtash Babadi,Robert F Padera,Sonya A MacParland,Gary D Bader,Nasser Imad,Isaac H Solomon,Eric Miller,Stefan Riedel,Caroline B M Porter,Alexandra-Chloé Villani,Linus T-Y Tsai,Winston Hide,Gyongyi Szabo,Jonathan Hecht,Orit Rozenblatt-Rosen,Alex K Shalek,Benjamin Izar,Aviv Regev,Yury V Popov,Z Gordon Jiang,Ioannis S Vlachos
Source:
Genome biology
Acute-on-chronic liver failure (ACLF): the 'Kyoto Consensus'-steps from Asia
February 17, 2025
Author(s):
Ashok Choudhury,Anand V Kulkarni,Vinod Arora,A S Soin,Abdul Kadir Dokmeci,Abhijeet Chowdhury,Abraham Koshy,Ajay Duseja,Ajay Kumar,Ajay Kumar Mishra,Ajay Kumar Patwa,Ajit Sood,Akash Roy,Akash Shukla,Albert Chan,Aleksander Krag,Amar Mukund,Ameet Mandot,Amit Goel,Amna Subhan Butt,Amrish Sahney,Ananta Shrestha,Andrés Cárdenas,Angelo Di Giorgio,Anil Arora,Anil Chandra Anand,Anil Dhawan,Ankur Jindal,Anoop Saraya,Anshu Srivastava,Anupam Kumar,Apichat Kaewdech,Apurva Pande,Archana Rastogi,Arun Valsan,Ashish Goel,Ashish Kumar,Ashwani K Singal,Atsushi Tanaka,Audrey Coilly,Ayaskanta Singh,Babu Lal Meena,Barath Jagadisan,Barjesh Chander Sharma,Bikrant Bihari Lal,C E Eapen,Cesar Yaghi,Chandan Kumar Kedarisetty,Chang Wook Kim,Charles Panackel,Chen Yu,Chetan R Kalal,Chhagan Bihari,Chien Hao Huang,Chitranshu Vasishtha,Christian Jansen,Christian Strassburg,Chun Yen Lin,Constantine J Karvellas,Cosmas Rinaldi Adithya Lesmana,Cyriac Abby Philips,Debbie Shawcross,Dharmesh Kapoor,Dhiraj Agrawal,Diana Alcantara Payawal,Dibya Lochan Praharaj,Dinesh Jothimani,Do Seon Song,Dong Joon Kim,Dong-Sik Kim,Duan Zhongping,Fazal Karim,Francois Durand,Gamal E Shiha,Gennaro D'Amico,George K Lau,Girish Kumar Pati,Graciela Elia Castro Narro,Guan-Huei Lee,Gupse Adali,Guru Prasad Dhakal,Gyongyi Szabo,H C Lin,Hai Li,Hari Kumar Nair,Harshad Devarbhavi,Harshvardhan Tevethia,Hasmik Ghazinian,Hemamala Ilango,Hong Ling Yu,Irsan Hasan,J Fernandez,Jacob George,Jaideep Behari,James Fung,Jasmohan Bajaj,Jaya Benjamin,Jennifer C Lai,Jidong Jia,Jin Hua Hu,Jin Jun Chen,Jin Lin Hou,Jin Mo Yang,Johannes Chang,Jonel Trebicka,Jörg C Kalf,Jose D Sollano,Joy Varghese,Juan Pablo Arab,Jun Li,K Rajender Reddy,Kaiser Raja,Kalpana Panda,Kamal Kajal,Karan Kumar,Kaushal Madan,Kemal Fariz Kalista,Kessarin Thanapirom,Khin Maung Win,Ki Tae Suk,Krishnadas Devadas,Laurentius A Lesmana,Lubna Kamani,Madhumita Premkumar,Madunil A Niriella,Mamun Al Mahtab,Man Fung Yuen,Manal HEl Sayed,Manasa Alla,Manav Wadhawan,Manoj Kumar Sharma,Manoj Sahu,Manya Prasad,Mark Dhinesh Muthiah,Martin Schulz,Meenu Bajpai,Mettu Srinivas Reddy,Michael Praktiknjo,Ming Lung Yu,Mithra Prasad,Mithun Sharma,Mohamed Elbasiony,Mohammed Eslam,Mohd Golam Azam,Mohd Rela,Moreshwar S Desai,Mukul Vij,Nadim Mahmud,Narendra Singh Choudhary,Navin Kumar Marannan,Necati Ormeci,Neeraj Saraf,Nipun Verma,Nobuaki Nakayama,Norifumi Kawada,None Oidov Baatarkhuu,Omesh Goyal,Osamu Yokosuka,P N Rao,Paolo Angeli,Pathik Parikh,Patrick S Kamath,Paul J Thuluvath,Philipp Lingohr,Piyush Ranjan,Prashant Bhangui,Pravin Rathi,Puja Sakhuja,Puneet Puri,Qin Ning,R K Dhiman,Rahul Kumar,Rajan Vijayaraghavan,Rajeev Khanna,Rakhi Maiwall,Ravi Mohanka,Richard Moreau,Rino Alvani Gani,Rohit Loomba,Rohit Mehtani,Ruveena Bhavani Rajaram,S S Hamid,Sachin Palnitkar,Sadhna Lal,Sagnik Biswas,Sakkarin Chirapongsathorn,Samagra Agarwal,Sanjeev Sachdeva,Sanjiv Saigal,Santhosh E Kumar,Sargsyan Violeta,Satender Pal Singh,Satoshi Mochida,Saurabh Mukewar,Seema Alam,Seng Gee Lim,Shahinul Alam,None Shalimar,Shantan Venishetty,Shikha S Sundaram,Shiran Shetty,Shobna Bhatia,Shweta A Singh,Shyam Kottilil,Simone Strasser,S M Shasthry,Soe Thiha Maung,Soek Siam Tan,Sombat Treeprasertsuk,Sonal Asthana,Steffen Manekeller,Subhash Gupta,Subrat Kumar Acharya,Sudhamshu K C,Sudhir Maharshi,Sumeet Asrani,Sunil Dadhich,Sunil Taneja,Suprabhat Giri,Surender Singh,Tao Chen,Tarana Gupta,Tatsuo Kanda,Tawesak Tanwandee,Teerha Piratvishuth,Ulrich Spengler,V G Mohan Prasad,Vandana Midha,Venera Rakhmetova,Vicente Arroyo,Vikrant Sood,Vinay Kumar Br,Vincent Wai-Sun Wong,Viniyendra Pamecha,Virendra Singh,Vishwa Mohan Dayal,Vivek A Saraswat,WRay Kim,Wasim Jafri,Wenyi Gu,Wong Yu Jun,Xiaolong Qi,Yogesh K Chawla,Yoon Jun Kim,Yu Shi,Zaigham Abbas,Guresh Kumar,Shuichiro Shiina,Lai Wei,Masao Omata,Shiv Kumar Sarin,APASL-ACLF Research Consortium (AARC) for APASL-ACLF working party
Source:
Hepatology international
A Novel Multi-organ Male Model of Alcohol-induced Acute-on-chronic Liver Failure Reveals NET-mediated Hepatocellular Death, Which is Prevented by RIPK3 Inhibition
December 22, 2024
Author(s):
Martí Ortega-Ribera,Yuan Zhuang,Mrigya Babuta,Veronika Brezani,Radhika S Joshi,Zsuzsanna Zsengeller,Prashanth Thevkar Nagesh,Yanbo Wang,Roderick Bronson,Gyongyi Szabo
Source:
Cellular and molecular gastroenterology and hepatology
miR-21: A therapeutic target for delaying severe liver disease and hepatocellular carcinoma in high-fat-diet-fed mice
October 10, 2024
Author(s):
Urmila Jagtap,Anan Quan,Yuho Ono,Jonathan Lee,Kylie A Shen,Sergei Manakov,Gyongyi Szabo,Imad Nasser,Frank J Slack
Source:
bioRxiv : the preprint server for biology
Efficacy and Safety of Erenumab for Nonopioid Medication Overuse Headache in Chronic Migraine: A Phase 4, Randomized, Placebo-Controlled Trial
September 16, 2024
Author(s):
Stewart J Tepper,David W Dodick,Michel Lanteri-Minet,David Dolezil,Raquel Gil-Gouveia,Christian Lucas,Karolina Piasecka-Stryczynska,Gyöngyi Szabó,Daniel D Mikol,Mahan Chehrenama,Denise E Chou,Yiping Yang,Gabriel Paiva da Silva Lima
Source:
JAMA neurology
IRF3 regulates neuroinflammatory responses and the expression of genes associated with Alzheimer's disease
August 30, 2024
Author(s):
Radhika Joshi,Veronika Brezani,Gabrielle M Mey,Sergi Guixé-Muntet,Marti Ortega-Ribera,Yuan Zhuang,Adam Zivny,Sebastian Werneburg,Jordi Gracia-Sancho,Gyongyi Szabo
Source:
Journal of neuroinflammation
In vivo Bruton's tyrosine kinase inhibition attenuates alcohol-associated liver disease by regulating CD84-mediated granulopoiesis
August 07, 2024
Author(s):
Prashanth Thevkar Nagesh,Yeonhee Cho,Yuan Zhuang,Mrigya Babuta,Marti Ortega-Ribera,Radhika Joshi,Veronika Brezani,Arman Patel,Aditi Ashish Datta,Viliam Brezani,Yun-Cheng Hsieh,Adriana Ramos,Jeeval Mehta,Christopher Copeland,Eleni Kanata,Zhenghui Gordon Jiang,Ioannis Vlachos,John Asara,AlcHepNet Consortium,Gyongyi Szabo
Source:
Science translational medicine
Acute kidney injury in severe alcohol-associated hepatitis treated with anakinra plus zinc or prednisone
July 19, 2024
Author(s):
Kavish R Patidar,Wanzhu Tu,Thomas G Cotter,Douglas A Simonetto,Amon Asgharpour,Muhammad Y Jan,Qing Tang,Yunpeng Yu,Yang Li,Moyinoluwa Taiwo,Prashanth Thevkar Nagesh,Srinivasan Dasarathy,Patrick S Kamath,Craig J McClain,Naga Chalasani,Gyongyi Szabo,Ramon Bataller,Mack Mitchell,Wajahat Z Mehal,Laura E Nagy,Vijay H Shah,Samer Gawrieh,Arun J Sanyal,AlcHepNet Investigators
Source:
Hepatology (Baltimore, Md.)
Reply: Exercise greater caution in bile acid research
July 17, 2024
Author(s):
Yuan Zhuang,Marti Ortega-Ribera,Gyongyi Szabo
Source:
Hepatology (Baltimore, Md.)
Inflammasomes in chronic liver disease: Hepatic injury, fibrosis progression and systemic inflammation
June 22, 2024
Author(s):
Vlad Taru,Gyongyi Szabo,Wajahat Mehal,Thomas Reiberger
Source:
Journal of hepatology
A novel experimental model of MetALD in male mice recapitulates key features of severe alcohol-associated hepatitis
June 19, 2024
Author(s):
Mrigya Babuta,Caroline Morel,Marcelle de Carvalho Ribeiro,Aditi Ashish Datta,Charles Calenda,Christopher Copeland,Imad Nasser,Gyongyi Szabo
Source:
Hepatology communications
Combined Insults of a MASH Diet and Alcohol Binges Activate Intercellular Communication and Neutrophil Recruitment via the NLRP3-IL-1β Axis in the Liver
June 19, 2024
Author(s):
Mrigya Babuta,Prashanth Thevkar Nagesh,Aditi Ashish Datta,Victoria Remotti,Yuan Zhuang,Jeeval Mehta,Francesca Lami,Yanbo Wang,Gyongyi Szabo
Source:
Cells
Neutrophil extracellular traps activate hepatic stellate cells and monocytes via NLRP3 sensing in alcohol-induced acceleration of MASH fibrosis
May 22, 2024
Author(s):
Mrigya Babuta,Caroline Morel,Marcelle de Carvalho Ribeiro,Charles Calenda,Martí Ortega-Ribera,Prashanth Thevkar Nagesh,Christopher Copeland,Yuan Zhuang,Yanbo Wang,Yeonhee Cho,Radhika Joshi,Viliam Brezani,Danielle Hawryluk,Aditi Ashish Datta,Jeeval Mehta,Imad Nasser,Gyongyi Szabo
Source:
Gut
Alcohol-Associated Liver Disease Outcomes: Critical Mechanisms of Liver Injury Progression
April 27, 2024
Author(s):
Natalia A Osna,Irina Tikhanovich,Martí Ortega-Ribera,Sebastian Mueller,Chaowen Zheng,Johannes Mueller,Siyuan Li,Sadatsugu Sakane,Raquel Carvalho Gontijo Weber,Hyun Young Kim,Wonseok Lee,Souradipta Ganguly,Yusuke Kimura,Xiao Liu,Debanjan Dhar,Karin Diggle,David A Brenner,Tatiana Kisseleva,Neha Attal,Iain H McKillop,Shilpa Chokshi,Ram Mahato,Karuna Rasineni,Gyongyi Szabo,Kusum K Kharbanda
Source:
Biomolecules
IRF3 regulates neuroinflammatory responses and the expression of genes associated with Alzheimer's disease
April 24, 2024
Author(s):
Radhika Joshi,Veronika Brezani,Gabrielle M Mey,Sergi Guixé-Muntet,Marti Ortega-Ribera,Yuan Zhuang,Adam Zivny,Sebastian Werneburg,Jordi Gracia-Sancho,Gyongyi Szabo
Source:
bioRxiv : the preprint server for biology
Proteomics identifies complement protein signatures in patients with alcohol-associated hepatitis
April 04, 2024
Author(s):
Moyinoluwa Taiwo,Emily Huang,Vai Pathak,Annette Bellar,Nicole Welch,Jaividhya Dasarathy,David Streem,Craig J McClain,Mack C Mitchell,Bruce A Barton,Gyongyi Szabo,Srinivasan Dasarathy,Alcohol Hepatitis Network (AlcHepNet) Consortium,Esperance A Schaefer,Jay Luther,Le Z Day,Xinshou Ouyang,Arumugam Suyavaran,Wajahat Z Mehal,Jon M Jacobs,Russell P Goodman,Daniel M Rotroff,Laura E Nagy
Source:
JCI insight
Reply: How does bile acid-induced IRF3 phosphorylation mediate cholestatic liver and kidney injury?-More needs to be known
March 05, 2024
Author(s):
Yuan Zhuang,Gyongyi Szabo
Source:
Hepatology (Baltimore, Md.)
G-CSF increases calprotectin expression, liver damage and neuroinflammation in a murine model of alcohol-induced ACLF
February 29, 2024
Author(s):
Martí Ortega-Ribera,Yuan Zhuang,Veronika Brezani,Prashanth Thevkar Nagesh,Radhika S Joshi,Mrigya Babuta,Yanbo Wang,Gyongyi Szabo
Source:
Frontiers in cell and developmental biology
Effects of a TAML catalyst on mice exposed during pregnancy and lactation
February 15, 2024
Author(s):
Laura N Vandenberg,Joshua P Mogus,Gillian K Szabo
Source:
Reproductive toxicology (Elmsford, N.Y.)
Randomized trial of anakinra plus zinc vs. prednisone for severe alcohol-associated hepatitis
February 11, 2024
Author(s):
Samer Gawrieh,Srinivasan Dasarathy,Wanzhu Tu,Patrick S Kamath,Naga P Chalasani,Craig J McClain,Ramon Bataller,Gyongyi Szabo,Qing Tang,Svetlana Radaeva,Bruce Barton,Laura E Nagy,Vijay H Shah,Arun J Sanyal,Mack C Mitchell,AlcHepNet Investigators
Source:
Journal of hepatology
Effects of perinatal exposures to a TAML catalyst on the mammary gland and hormone-sensitive outcomes in male mice
December 01, 2023
Author(s):
Gillian K Szabo,Joshua P Mogus,Laura N Vandenberg
Source:
Reproductive toxicology (Elmsford, N.Y.)
A novel score of IL-13 and age predicts 90-day mortality in severe alcohol-associated hepatitis: A multicenter plasma biomarker analysis
November 23, 2023
Author(s):
David Tornai,Mack Mitchell,Craig J McClain,Srinivasan Dasarathy,Arthur McCullough,Svetlana Radaeva,Aimee Kroll-Desrosiers,JungAe Lee,Bruce Barton,Gyongyi Szabo
Source:
Hepatology communications
Reply: Alcohol-induced extracellular ASC specks perpetuate liver inflammation and damage in alcohol-associated hepatitis even after alcohol cessation
November 16, 2023
Author(s):
Marcelle de Carvalho Ribeiro,Mrigya Babuta,Gyongyi Szabo
Source:
Hepatology (Baltimore, Md.)
Dysregulated meta-organismal metabolism of aromatic amino acids in alcohol-associated liver disease
October 11, 2023
Author(s):
Marko Mrdjen,Emily Huang,Vai Pathak,Annette Bellar,Nicole Welch,Jaividhya Dasarathy,David Streem,Craig J McClain,Mack Mitchell,Svetlana Radaeva,Bruce Barton,Gyongyi Szabo,Srinivasan Dasarathy,Zeneng Wang,Stanley L Hazen,J Mark Brown,Laura E Nagy
Source:
Hepatology communications
Bile acid-induced IRF3 phosphorylation mediates cell death, inflammatory responses, and fibrosis in cholestasis-induced liver and kidney injury via regulation of ZBP1
September 19, 2023
Author(s):
Yuan Zhuang,Martí Ortega-Ribera,Prashanth Thevkar Nagesh,Radhika Joshi,Huihui Huang,Yanbo Wang,Adam Zivny,Jeeval Mehta,Samir M Parikh,Gyongyi Szabo
Source:
Hepatology (Baltimore, Md.)
Skeletal Muscle Function Is Altered in Male Mice on Low-Dose Androgen Receptor Antagonist or Estrogen Receptor Agonist
August 26, 2023
Author(s):
Brent A Momb,Gillian K Szabo,Joshua P Mogus,Stuart R Chipkin,Laura N Vandenberg,Mark S Miller
Source:
Endocrinology
Therapeutic inhibition of miR-155 attenuates liver fibrosis via STAT3 signaling
August 07, 2023
Author(s):
Shashi Bala,Yuan Zhuang,Prashanth Thevkar Nagesh,Donna Catalano,Adam Zivny,Yanbo Wang,Jun Xie,Guangping Gao,Gyongyi Szabo
Source:
Molecular therapy. Nucleic acids
Prolonged hypoxia alleviates prolyl hydroxylation-mediated suppression of RIPK1 to promote necroptosis and inflammation
July 03, 2023
Author(s):
Tao Zhang,Daichao Xu,Jianping Liu,Min Wang,Li-Juan Duan,Min Liu,Huyan Meng,Yuan Zhuang,Huibing Wang,Yingnan Wang,Mingming Lv,Zhengyi Zhang,Jia Hu,Linyu Shi,Rui Guo,Xingxing Xie,Hui Liu,Emily Erickson,Yaru Wang,Wenyu Yu,Fabin Dang,Dongxian Guan,Cong Jiang,Xiaoming Dai,Hiroyuki Inuzuka,Peiqiang Yan,Jingchao Wang,Mrigya Babuta,Gewei Lian,Zhenbo Tu,Ji Miao,Gyongyi Szabo,Guo-Hua Fong,Antoine E Karnoub,Yu-Ru Lee,Lifeng Pan,William G Kaelin,Junying Yuan,Wenyi Wei
Source:
Nature cell biology
Protective role of cGAS in NASH is related to the maintenance of intestinal homeostasis
May 24, 2023
Author(s):
Marcelle de Carvalho Ribeiro,Yeonhee Cho,Jeeval Mehta,Xiaojing Wang,Mrigya Babuta,Christopher Copeland,Hosni Hussein,Donna Catalano,Yanbo Wang,Gyongyi Szabo
Source:
Liver international : official journal of the International Association for the Study of the Liver
The Beneficial Effects of Lactobacillus GG Therapy on Liver and Drinking Assessments in Patients with Moderate Alcohol-Associated Hepatitis
April 11, 2023
Author(s):
Vatsalya Vatsalya,Wenke Feng,Maiying Kong,Huirong Hu,Gyongyi Szabo,Arthur McCullough,Srinivasan Dasarathy,Laura E Nagy,Svetlana Radaeva,Bruce Barton,Mack Mitchell,Craig J McClain
Source:
The American journal of gastroenterology
Safety, Pharmacokinetics, and Efficacy Signals of Larsucosterol (DUR-928) in Alcohol-Associated Hepatitis
April 03, 2023
Author(s):
Tarek Hassanein,Craig J McClain,Vatsalya Vatsalya,Lance L Stein,Steven L Flamm,Paul Martin,Matthew C Cave,Mack Mitchell,Bruce Barton,Laura Nagy,Gyongyi Szabo,Arthur McCullough,Srinivasin Dasarathy,Jaymin Shah,Christina Blevins,Deborah Scott,William Krebs,James E Brown,WeiQi Lin
Source:
The American journal of gastroenterology
Alcohol-induced extracellular ASC specks perpetuate liver inflammation and damage in alcohol-associated hepatitis even after alcohol cessation
March 02, 2023
Author(s):
Marcelle de Carvalho Ribeiro,Arvin Iracheta-Vellve,Mrigya Babuta,Charles D Calenda,Christopher Copeland,Yuan Zhuang,Patrick P Lowe,Danielle Hawryluk,Donna Catalano,Yeonhee Cho,Bruce Barton,Srinivasan Dasarathy,Craig McClain,Arthur J McCullough,Mack C Mitchell,Laura E Nagy,Svetlana Radaeva,Egil Lien,Douglas T Golenbock,Gyongyi Szabo
Source:
Hepatology (Baltimore, Md.)
Reply
February 23, 2023
Author(s):
Gyongyi Szabo,Mack C Mitchell,Srinivasan Dasarathy,Craig McClain
Source:
Hepatology (Baltimore, Md.)
Design of a multicenter randomized clinical trial for treatment of Alcohol-Associated Hepatitis
January 26, 2023
Author(s):
Wanzhu Tu,Samer Gawrieh,Srinivasan Dasarathy,Mack C Mitchell,Douglas A Simonetto,Kavish R Patidar,Craig J McClain,Ramon Bataller,Gyongyi Szabo,Qing Tang,Bruce A Barton,Svetlana Radaeva,Arun J Sanyal,Vijay Shah,Alcoholic Hepatitis Network (AlcHepNet) Investigators
Source:
Contemporary clinical trials communications
Differential role of MLKL in alcohol-associated and non-alcohol-associated fatty liver diseases in mice and humans
December 08, 2022
Author(s):
Tatsunori Miyata,Xiaoqin Wu,Xiude Fan,Emily Huang,Carlos Sanz-Garcia,Christina K Cajigas-Du Ross,Sanjoy Roychowdhury,Annette Bellar,Megan R McMullen,Jaividhya Dasarathy,Daniela S Allende,Joan Caballeria,Pau Sancho-Bru,Craig J McClain,Mack Mitchell,Arthur J McCullough,Svetlana Radaeva,Bruce Barton,Gyongyi Szabo,Srinivasan Dasarathy,Laura E Nagy
Source:
JCI insight
A single-nucleus and spatial transcriptomic atlas of the COVID-19 liver reveals topological, functional, and regenerative organ disruption in patients
November 03, 2022
Author(s):
Yered Pita-Juarez,Dimitra Karagkouni,Nikolaos Kalavros,Johannes C Melms,Sebastian Niezen,Toni M Delorey,Adam L Essene,Olga R Brook,Deepti Pant,Disha Skelton-Badlani,Pourya Naderi,Pinzhu Huang,Liuliu Pan,Tyler Hether,Tallulah S Andrews,Carly G K Ziegler,Jason Reeves,Andriy Myloserdnyy,Rachel Chen,Andy Nam,Stefan Phelan,Yan Liang,Amit Dipak Amin,Jana Biermann,Hanina Hibshoosh,Molly Veregge,Zachary Kramer,Christopher Jacobs,Yusuf Yalcin,Devan Phillips,Michal Slyper,Ayshwarya Subramanian,Orr Ashenberg,Zohar Bloom-Ackermann,Victoria M Tran,James Gomez,Alexander Sturm,Shuting Zhang,Stephen J Fleming,Sarah Warren,Joseph Beechem,Deborah Hung,Mehrtash Babadi,Robert F Padera,Sonya A MacParland,Gary D Bader,Nasser Imad,Isaac H Solomon,Eric Miller,Stefan Riedel,Caroline B M Porter,Alexandra-Chloé Villani,Linus T-Y Tsai,Winston Hide,Gyongyi Szabo,Jonathan Hecht,Orit Rozenblatt-Rosen,Alex K Shalek,Benjamin Izar,Aviv Regev,Yury Popov,Z Gordon Jiang,Ioannis S Vlachos
Source:
bioRxiv : the preprint server for biology
Innate immune activation: Parallels in alcohol use disorder and Alzheimer's disease
September 26, 2022
Author(s):
Adriana Ramos,Radhika S Joshi,Gyongyi Szabo
Source:
Frontiers in molecular neuroscience
Neutrophil extracellular traps contribute to liver damage and increase defective low-density neutrophils in alcohol-associated hepatitis
September 05, 2022
Author(s):
Yeonhee Cho,Terence Ndonyi Bukong,David Tornai,Mrigya Babuta,Ioannis S Vlachos,Eleni Kanata,Donna Catalano,Gyongyi Szabo
Source:
Journal of hepatology
Transcriptional regulation of Acsl1 by CHREBP and NF-kappa B in macrophages during hyperglycemia and inflammation
September 02, 2022
Author(s):
Prashanth Thevkar-Nagesh,Justine Habault,Maud Voisin,Sophie E Ruff,Susan Ha,Rachel Ruoff,Xi Chen,Shruti Rawal,Tarik Zahr,Gyongyi Szabo,Inez Rogatsky,Edward A Fisher,Michael J Garabedian
Source:
PloS one
Granulocyte colony-stimulating factor attenuates liver damage by M2 macrophage polarization and hepatocyte proliferation in alcoholic hepatitis in mice
August 23, 2022
Author(s):
Yeonhee Cho,Radhika Joshi,Patrick Lowe,Christopher Copeland,Marcelle Ribeiro,Caroline Morel,Donna Catalano,Gyongyi Szabo
Source:
Hepatology communications
Altered ethanol metabolism and increased oxidative stress enhance alcohol-associated liver injury in farnesoid X receptor-deficient mice
July 23, 2022
Author(s):
Caroline Morel,Vivek Chowdhary,Prashanth Thevkar Nagesh,Marcelle Ribeiro,Danielle Hawryluk,Donna Catalano,Luciano Adorini,Gyongyi Szabo
Source:
Liver international : official journal of the International Association for the Study of the Liver
Reply
July 01, 2022
Author(s):
Gyongyi Szabo,Mack Mitchell,Craig J McClain,Srinivasan Dasarathy,Bruce Barton,Arthur J McCullough,Laura E Nagy,Aimee Kroll-Desrosiers,David Tornai,Hyesung Alice Min,Svetlana Radaeva,Lisa Casey,Jennifer Cuthbert
Source:
Hepatology (Baltimore, Md.)
Best practices to quantify the impact of reproductive toxicants on development, function, and diseases of the rodent mammary gland
June 28, 2022
Author(s):
Klara Matouskova,Gillian K Szabo,Jessica Daum,Suzanne E Fenton,Sofie Christiansen,Ana M Soto,Jennifer E Kay,Bethsaida Cardona,Laura N Vandenberg
Source:
Reproductive toxicology (Elmsford, N.Y.)
Review article: vascular effects of PPARs in the context of NASH
June 06, 2022
Author(s):
Sergi Guixé-Muntet,Louise Biquard,Gyongyi Szabo,Jean-François Dufour,Frank Tacke,Sven Francque,Pierre-Emmanuel Rautou,Jordi Gracia-Sancho
Source:
Alimentary pharmacology & therapeutics
Therapeutic advances in alcohol-associated hepatitis
May 19, 2022
Author(s):
Gyongyi Szabo,Mark Thursz,Vijay H Shah
Source:
Journal of hepatology
IL-1 receptor antagonist plus pentoxifylline and zinc for severe alcohol-associated hepatitis
March 27, 2022
Author(s):
Gyongyi Szabo,Mack Mitchell,Craig J McClain,Srinivasan Dasarathy,Bruce Barton,Arthur J McCullough,Laura E Nagy,Aimee Kroll-Desrosiers,David Tornai,Hyesung Alice Min,Svetlana Radaeva,M E Blair Holbein,Lisa Casey,Jennifer Cuthbert
Source:
Hepatology (Baltimore, Md.)
Cell-to-Cell Communications in Alcohol-Associated Liver Disease
March 10, 2022
Author(s):
Natalia A Osna,Akiko Eguchi,Ariel E Feldstein,Hidekazu Tsukamoto,Raghubendra S Dagur,Murali Ganesan,Moses New-Aaron,Madan Kumar Arumugam,Srinivas Chava,Marcelle Ribeiro,Gyongyi Szabo,Sebastian Mueller,Shijin Wang,Cheng Chen,Steven A Weinman,Kusum K Kharbanda
Source:
Frontiers in physiology
Alcohol Promotes Exosome Biogenesis and Release via Modulating Rabs and miR-192 Expression in Human Hepatocytes
January 31, 2022
Author(s):
Shashi Bala,Mrigya Babuta,Donna Catalano,Aman Saiju,Gyongyi Szabo
Source:
Frontiers in cell and developmental biology
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