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Neuropathology Web Page

Director, Thomas Smith, MD   

Consultative Services
Specimen Requirements
Contact Information 

Consultative Services

The Neuropathology service provides diagnostic evaluation of adult and pediatric central nervous system and neuromuscular disorders.  

The consultation services include:

  1. Evaluation of surgical specimens of neoplastic and non-neoplastic disorders of brain and spinal cord utilizing standard histology as well as immunohistochemistry, electron microscopy and molecular diagnostics 
  2. Evaluation of brain and spinal cord pathology in autopsy specimens 
  3. Evaluation of nerve and muscle biopsies by standard histology, enzyme histochemistry, immunohistochemistry and electron microscopy 
  4. Electron microscopic evaluation of diagnostic skin biopsies for neurologic disorders (e.g. CADASIL). 

The types of specimens that may be submitted include: fresh and fixed (formalin, glutaraldehyde) tissue, paraffin blocks, and slides. 

Specific procedures are required for submission of nerve and muscle biopsies (see link to Specimen Requirements and Transportation)


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Dr. Tom Smith

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 Specimen Requirements

  • Paraffin block or unstained slides and one H&E 
  • Fresh tissue – call Lab at 508-793-6210 to make arrangements 

Send specimens to:

UMass Memorial Hospital Labs
365 Plantation Street
Worcester, MA  01605

For assistance with consultation cases please call the Main Office at 508-793-6100

For assistance with billing issues please call Lou Savas at 508-793-6204

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Contact Information

Director: Dr. Thomas Smith
Division of Anatomic Pathology
Three Biotech
One Innovation Drive
Worcester, MA 01605
Tel: 508-793-6100

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