May 31, 2023
Graduation 2023!
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Molecular illustrations on this webpage were generated by Leonora Martínez-Núñez, PhD.
We study the regulation of membrane trafficking, in particular the mechanistic basis for the regulation of spatial and temporal specificity.
We utilize a multifaceted approach that combines biochemistry, structural biology, cell biology, and biophysical techniques in a variety of model organisms.
We are a group of diverse researchers who work together to create an inclusive, and collaborative environment where we can all thrive scientifically, professionally, and personally
We are committed to creating a diverse, equitable, and inclusive culture that helps foster scientific discovery and enriches our lab culture through expanding viewpoints, countering biases, and offering unique approaches and ideas.
Exocyst stimulates each step of exocytic SNARE complex assembly and vesicle fusion.
Lee C, Lepore D, Lee SH, Kim TG, Buwa N, Lee J, Munson M, Yoon TY.
Nat Struct Mol Biol. 2024 Sep 6. doi: 10.1038/s41594-024-01388-2. Epub ahead of print. PMID: 39242980.
Exposing the elusive exocyst structure
Lepore DM, Martínez-Núñez L, Munson M.
Trends Biochem Sci. 2018 Sep;43(9):714-725. doi: 10.1016/j.tibs.2018.06.012. Epub 2018 Jul 25. PMID: 30055895; PMCID: PMC6108956.
Subunit connectivity, assembly determinants and architecture of the yeast exocyst complex
Heider MR, Gu M, Duffy CM, Mirza AM, Marcotte LL, Walls AC, Farrall N, Hakhverdyan Z, Field MC, Rout MP, Frost A, Munson M.
Nat Struct Mol Biol. 2016 Jan;23(1):59-66. doi: 10.1038/nsmb.3146. Epub 2015 Dec 14. PMID: 26656853; PMCID: PMC4752824.
Molecular illustrations on this webpage were generated by Leonora Martínez-Núñez, PhD.