Search the New Massi Lab site site

Page Menu

Our most recent publications:

Total: displaying 10 out of 15 results

A Hydrophobic Core Stabilizes the Residual Structure in the RRM2 Intermediate State of the ALS-linked Protein TDP-43

Saturday, October 19, 2024

Author(s): Brian C Mackness,Brittany R Morgan,Laura M Deveau,Sagar V Kathuria,Jill A Zitzewitz,Francesca Massi

Source: Journal of molecular biology
Structure and Dynamics of the CCCH-Type Tandem Zinc Finger Domain of POS-1 and Implications for RNA Binding Specificity

Wednesday, September 25, 2024

Author(s): Asli Ertekin,Brittany R Morgan,Sean P Ryder,Francesca Massi

Source: Biochemistry
A hydrophobic core stabilizes the residual structure in the RRM2 intermediate state of the ALS-linked protein TDP-43

Tuesday, June 25, 2024

Author(s): Brian C Mackness,Brittany R Morgan,Laura M Deveau,Sagar V Kathuria,Jill A Zitzewitz,Francesca Massi

Source: bioRxiv : the preprint server for biology
Expression of ALS-PFN1 impairs vesicular degradation in iPSC-derived microglia

Thursday, March 21, 2024

Author(s): Salome Funes,Jonathan Jung,Del Hayden Gadd,Michelle Mosqueda,Jianjun Zhong,None Shankaracharya,Matthew Unger,Karly Stallworth,Debra Cameron,Melissa S Rotunno,Pepper Dawes,Megan Fowler-Magaw,Pamela J K...

Source: Nature communications
A nematode model to evaluate microdeletion phenotype expression

Monday, November 13, 2023

Author(s): Katianna R Antkowiak,Peren Coskun,Sharon T Noronha,Davide Tavella,Francesca Massi,Sean P Ryder

Source: G3 (Bethesda, Md.)
Expression of ALS-PFN1 impairs vesicular degradation in iPSC-derived microglia

Monday, July 03, 2023

Author(s): Salome Funes,Del Hayden Gadd,Michelle Mosqueda,Jianjun Zhong,Jonathan Jung,None Shankaracharya,Matthew Unger,Debra Cameron,Pepper Dawes,Pamela J Keagle,Justin A McDonough,Sivakumar Boopathy,Miguel Sen...

Source: bioRxiv : the preprint server for biology
The Role of Substrate Mediated Allostery in the Catalytic Competency of the Bacterial Oligosaccharyltransferase PglB

Monday, October 04, 2021

Author(s): Brittany R Morgan,Francesca Massi

Source: Frontiers in molecular biosciences
ALS-linked PFN1 variants exhibit loss and gain of functions in the context of formin-induced actin polymerization

Wednesday, June 02, 2021

Author(s): Eric J Schmidt,Salome Funes,Jeanne E McKeon,Brittany R Morgan,Sivakumar Boopathy,Lauren C O'Connor,Osman Bilsel,Francesca Massi,Antoine Jégou,Daryl A Bosco

Source: Proceedings of the National Academy of Sciences of the United States of America
Analysis of Emerging Variants in Structured Regions of the SARS-CoV-2 Genome

Friday, May 21, 2021

Author(s): Sean P Ryder,Brittany R Morgan,Peren Coskun,Katianna Antkowiak,Francesca Massi

Source: Evolutionary bioinformatics online
Analysis of Rapidly Emerging Variants in Structured Regions of the SARS-CoV-2 Genome

Thursday, June 25, 2020

Author(s): Sean P Ryder,Brittany R Morgan,Francesca Massi

Source: bioRxiv : the preprint server for biology
A Disorder-to-Order Transition Mediates RNA Binding of the Caenorhabditis elegans Protein MEX-5

Thursday, April 16, 2020

Author(s): Davide Tavella,Asli Ertekin,Hila Schaal,Sean P Ryder,Francesca Massi

Source: Biophysical journal
Networks of electrostatic and hydrophobic interactions modulate the complex folding free energy surface of a designed βα protein

Sunday, March 17, 2019

Author(s): Sujit Basak,R Paul Nobrega,Davide Tavella,Laura M Deveau,Nobuyasu Koga,Rie Tatsumi-Koga,David Baker,Francesca Massi,C Robert Matthews

Source: Proceedings of the National Academy of Sciences of the United States of America
Characterization of TDP-43 RRM2 Partially Folded States and Their Significance to ALS Pathogenesis

Saturday, October 13, 2018

Author(s): Davide Tavella,Jill A Zitzewitz,Francesca Massi

Source: Biophysical journal
Characterizing Protein Dynamics with NMR R 1ρ Relaxation Experiments

Monday, November 20, 2017

Author(s): Francesca Massi,Jeffrey W Peng

Source: Methods in molecular biology (Clifton, N.J.)
Structural Rearrangement upon Fragmentation of the Stability Core of the ALS-Linked Protein TDP-43

Thursday, August 10, 2017

Author(s): Brittany R Morgan,Jill A Zitzewitz,Francesca Massi

Source: Biophysical journal

In the News

Latest BMB news as reported by the UMass Chan Communications Office

New research examines mechanisms of protein complex at basic cell biological level

January 14, 2025
PhD student among first to join UMass Chan program focused on quantitative skills

December 09, 2024
UMass Chan community invited to ponder meaning of ‘advancing together’ at art exhibit

September 25, 2024
UMass Memorial Health gift, with matching funds from UMass Foundation, to fund five new endowed chairs at UMass Chan

September 19, 2024
Convocation 2024: UMass Chan racing toward ambitious future

September 13, 2024
Morningside Graduate School of Biomedical Sciences celebrates largest class at qualifying exam ceremony

September 12, 2024
UMass Chan kicks off 2024 academic year with weeklong Convocation celebration

August 30, 2024
UMass Chan neuroscientist receives $4.1 million Transformative Research Award to study Down syndrome

July 16, 2024
UMass Chan BRIDGE Fund commits $2M in six faculty projects

July 03, 2024
Morningside Graduate School of Biomedical Sciences celebrates milestones of IMSD, PREP students

June 18, 2024
Advancing gender equity, importance of mentoring highlighted at Women’s Faculty Awards

May 24, 2024
Twenty rising faculty members graduate from Junior Faculty Development Program

May 17, 2024
Celia A. Schiffer elected to National Academy of Sciences

May 03, 2024
Mary Munson, Craig Peterson named American Association for the Advancement of Science fellows

April 18, 2024
Zhiping Weng named inaugural chair of the Department of Genomics & Computational Biology

November 03, 2023
Celebrating collaboration, UMass Chan launches ‘Advancing Together’ brand

September 06, 2023