Jul 31, 2024
Celebrating RNA Day with Dr. Thoru Pederson
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Our lab investigates the glycoslyation, assembly, structure, trafficking and function of ion channel complexes.
Electric signals play important roles in diseases ranging from cardiac arrhythmias to diabetes.
We utilize synthetic organic chemistry, glycobiology, biochemistry, and electrophysiology to elucidate the molecular underpinnings of ion channel proteins.
We are an enthusiastic group of researchers and innovators.
Wheat germ agglutinin-conjugated fluorescent pH sensors for visualizing proton fluxes.
Zhang L, Zhang M, Bellve K, Fogarty KE, Castro MA, Brauchi S, Kobertz WR.
J Gen Physiol. 2020 Jun 1;152(6):e201912498. doi: 10.1085/jgp.201912498. PMID: 31978216; PMCID: PMC7266149.
The Proton-Coupled Monocarboxylate Transporter Hermes Is Necessary for Autophagy during Cell Death.
Velentzas PD, Zhang L, Das G, Chang TK, Nelson C, Kobertz WR, Baehrecke EH.
Dev Cell. 2018 Nov 5;47(3):281-293.e4. doi: 10.1016/j.devcel.2018.09.015. Epub 2018 Oct 11. PMID: 30318245; PMCID: PMC6219939.
Palladium-Mediated Synthesis of a Near-Infrared Fluorescent K+ Sensor.
Bandara HMD, Hua Z, Zhang M, Pauff SM, Miller SC, Davie EAC, Kobertz WR.
J Org Chem. 2017 Aug 4;82(15):8199-8205. doi: 10.1021/acs.joc.7b00845. Epub 2017 Jul 14. PMID: 28664732; PMCID: PMC5715468.
