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Job Dekker, PhD

Research Focus - Mechanisms of Chromosome Folding

  • Determining the pathways by which cells build mitotic chromosomes and segregate sister chromatids 
  • Elucidating the molecular mechanisms by which cells fold their genomes during the cell cycle
  • Mapping how genomic rearrangements in cancer cells rewire enhancer-promoter interactions
  • Analyzing the impact of nuclear organization on DNA damage repair outcomes 

Representative Publication

Dixon JR, Xu J, Dileep V, et al. Integrative detection and analysis of structural variation in cancer genomes. Nature Genet. 2018;50(10):1388–1398.

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  • Job Dekker elected to National Academy of Sciences

    Job Dekker elected to National Academy of Sciences

    UMass Chan Medical School scientist Job Dekker, PhD, was elected to the National Academy of Sciences on May 3 for his contributions to the field of genomics.

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  • UMass Chan scientists to expand 4D nucleome research with $13 million NIH grants

    UMMS scientists to expand 4D nucleome research with $13 million NIH grants

    Investigators at UMass Medical School have received two, five-year grants totaling $13 million to explore how the 4D genome structure influences gene expression, cellular function, development and disease as it reshapes itself. Job Dekker, PhD, and Paul Kaufman, PhD, to investigate architecture of genome as it changes over time.

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  • Job Dekker elected to European Molecular Biology Organization

    Job Dekker elected to European Molecular Biology Organization

    The European Molecular Biology Organization (EMBO) has elected Job Dekker, PhD, to lifetime membership in the organization.

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