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C Robert Mathews

UMassMed Faculty Page


Title: A Versatile Microplate Design for High Performance Spectroscopic Applications. UMMS14-19; Patent Pending.

  • This novel technology describes a microplate for use in high-throughput determinations of protein stability, protein-DNA/RNA binding, and protein-protein associations. The disclosed invention overcomes the limitations of other microplate designs including meniscus formation, variable path length for each well, and compatibility with use in the UV and far-UV region. The invention uses two optical flats, which for example can be quartz glass, and a spacer having a plurality of holes defined in the spacer to make optical measurements. 


Innovation TopicsResearch ToolsProtein interactions and behavior