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Robert M Kotin

UMassMed Faculty Page


Title: Closed-ended Linear Duplex DNA (CELiD) for Non-Viral Gene Transfer: Methods, Materials, and Uses for Therapeutic Gene Transfer. UMMS16-18; Patent Pending.  

  • This invention provides a novel gene delivery vector that elicits little immune response and is not limited in carrying capacity. The invention discloses novel closed-ended linear DNA molecules suitable for long-term gene therapy and methods of delivery.


Innovation TopicsGene TherapyAAVGene therapy improvement