Stephen Heard, M.D.


Academic Role: Professor

Faculty Appointment(s) and Affiliations:
School of Medicine
Graduate School of Biomedical Sciences
Clinical and Population Health Research

Clinical Interests: Critical Care, Neuro Anesthesia, Research, Perioperative Outcomes Research

Phone: (508) 856-3266
Fax: (508) 856-3921


Academic Background

M.D. University of Texas, Houston, TX, 1978

Postdoctoral Training

Newton-Wellesley Hospital, Newton, MA, Residency in Internal Medicine, 1978-1981
University of Florida, Gainesville, FL, Residency in Anesthesiology, 1981-1983
University of Florida, Gainesville, FL, Fellowship in Critical Care Medicine, 1983-1984

Selected Publications

Koff MD, Brown JR, Marshall EJ, O'Malley AJ, Jensen J, Heard SO, Longtine K, O’Neill M, Longtine J, Houston D, Robison C, Moulton E, Patel HM, Loftus R. A Novel Hand Hygiene System Increases Hand Decontamination Frequency of Intraoperative Providers but Does Not Reduce Postoperative Healthcare-Associated Infections: a Multicenter, Randomized, and Controlled Clinical Trial. Infection Control Hosp EpidemiolInfect Control Hosp Epidemiol. 2016 Aug;37(8):888-95.

Walz JM, Ellison R, Mack D, Flaherty H, McIlwaine J, Whyte K, Landry K, Baker S, Heard SO; UMass Memorial, Critical Care Operations Committee Research Group. The bundle “plus”: effect of a multidisciplinary team approach to eradicate central line associated blood-stream infections (CLABSI). Anesth Analg. 2015;120:868-76. 

Mylonakis E, Clancy CJ, Ostrosky-Zeichner L, Garey KW, Alangaden GJ, Vazquez JA, Groeger JS, Judson MA, Vinagre Y, Heard SO, Zervou FN, Zacharioudakis IM, Kontoyiannis DM, Pappas PG. Magnetic resonance assay for the diagnosis of candidemia. Clin Infect Dis. 2015 Mar 15;60:892-9.

Caramiciu JA, Adams JP, McKown BT, French CD, Ruggieri E, Heard SO. Effects of an in-house coordinator and practitioner referral rather than proxy referral to an organ procurement organization following asystolic death on tissue donation rates. Transplant Proc. 2014;46:1274-80.

Zhao H, Heard SO, Mullen MT, Crawford S, Goldberg RJ, Frendl G, Lilly CM. An evaluation of the diagnostic accuracy of the 1991 ACCP/SCCM and the 2001 SCCM/ESICM/ACCP/ATS/SIS sepsis definition. Crit Care Med. 2012;40:1700-6.

Loftus RW, Koff MD, Reddy S, Heard SO, Patel HM, Fernandez PG, Beach ML, Brown JR, Corwin HL, Jensen JT, Kispert D, Huysman B, Dodds TM, Ruoff KL, Yeager MP. Multiple reservoirs contribute to intraoperative bacterial transmission. Anesth Analg. 2012;114:1236-48.

O'Grady NP, Alexander M, Burns LA, Dellinger EP, Garland J, Heard SO, Lipsett PA, Masur H, Mermel LA, Pearson ML, Raad II, Randolph AG, Rupp ME, Saint S.  Summary of recommendations:  guidelines for the prevention of intravascular catheter-related infections. Clin Infect Dis 2011; 52:1087-99.

Walz JM, Avelar RL, Longtine KJ, Carter KL, Mermel LA, Heard SO.  Anti-infective external coating of central venous catheters:  a randomized, noninferiority trial comparing 5-fluorouracil with chlorhexidine/silver sulfadiazine in preventing catheter colonization.  Crit Care Med 2010; 38:2095-102.

Watson NC, Heard SO.  The use of lactate as a biomarker.  J Intensive Care Med 2010; 25:301-2.

Jones N, Cocchiarella A, Faris K, Heard SO.  Pancreatitis associated with Strongyloides stercoralis infection in a patient chronically treated with corticosteroids.  J Intensive Care Med 2010; 25:172-4.

Matheos T, Walz JM, Adams JP, Johnson K, Longtine K, Longtine J, O'Neill M, Heard SO. Comparison of the duration of antimicrobial activity of 2 different antimicrobial central venous catheters.  Infect Control Hosp Epidemiol 2010; 31:295-7.

Walz JM, Memtsoudis SG, Heard SO.  Analytic reviews: prevention of central venous catheter bloodstream infections.  J Intensive Care Med 2010; 25:131-8.

Walz JM, Faris K, Heard SO.  Who let the bugs in?  Crit Care Med 2008; 36:2689-90.

Soller BR, Ryan KL, Rickards CA, Cooke WH, Yang Y, Soyemi OO, Crookes BA, Heard SO, Convertino VA.  Oxygen saturation determined from deep muscle, not thenar tissue, is an early indicator of central hypovolemia in humans.  Crit Care Med 2008; 36:176-82.

Soller BR, Yang Y, Soyemi OO, Ryan KL, Rickards CA, Walz, JM, Heard SO, Convertino VA. Noninvasively determined muscle oxygen saturation is an early indicator of central hypovolemia in humans. J Appl Physiol 2008; 104:475-81.

Corwin HL, Gettinger A, Fabian TC, May A, Pearl RG, Heard SO, et al. Efficacy and safety of epoetin alfa in critically ill patients. New Engl J Med 2007; 357:965-976.

Bernat JL, D’Alessandro AM, Port FK, Bleck TP, Heard SO, et al. Report of national conference on donation after cardiac death. Am J Transplant 2006; 6:281-291.

Heard SO, Munson EL, Doern GV. Exposure of bacteria to antimicrobial impregnated central venous catheters does not directly lead to the emergence of antimicrobial resistance. Chest 2004; 126:1628-1635.

Soller BR, Idwasi PO, Balaguer J, Levin S, Simsir SA, Vander Salm TJ, Collette H, Heard SO. Noninvasive, NIRS-Measured Muscle pH and PO2 Indicate Tissue Perfusion for Cardiac Surgical Patients on Cardiopulmonary Bypass. Critical Care Medicine 2003; 31:2324-2331.

Soller BR, Kahn T, Favreau J, His C, Puyana JC, Heard SO. Investigation of muscle pH as an indication of liver pH and injury from hemorrhagic shock. J Surg Res 2003; 114:195-201.

Dickson EW, Doern GV, Trevino L, Mazzoni M, Heard SO. Prevention of descending pneumonia in rats with perflubron-delivered tobramycin. Acad Emerg Med 2003; 10:1019-1023.

Smyrnios NA, Irwin RS, Connolly AE, Wilson MM, Curley FJ, French CL, Heard SO. Effects of a multifaceted, multidisciplinary, hospital-wide quality improvement program on weaning from mechanical ventilation. Crit Care Med 2002; 30(6):1224-1230.

Soller BR, Cingo N, Puyana JC, Khan T, Hsi C, Kim H, Favreau J, Heard SO. Simultaneous measurement of hepatic tissue pH, venous oxygen saturation and hemoglobin by near infrared spectroscopy. Shock 2001; 15:106-111.

Talke P, Chen R, Thomas B, Aggarwall A, Gottlieb A, Thorborg P, Heard S. Hemodynamic and adrenergic effects of dexmedetomidine after vascular surgery. Anesth Analg 2000; 90:834-839.

Abraham E, Baughman R, Fletcher E, Heard S, et al. Liposomal prostaglandin E1 (TLC C-53) in adult respiratory distress syndrome (ARDS): A controlled, randomized, double-blind, multi-center clinical trial. Crit Care Med 1999; 27:1478-1485.

Heard SO, Longtine K, Toth I, Puyana JC, Potenza B, Smyrnios N. The influence of liposomal-encapsulated prostaglandin E1 on hydrogen peroxide concentrations in the exhaled breath of patients with the acute respiratory distress syndrome ARDS. Anesth Analg 1999; 89:353-357.

Darouiche RO, Raad II, Heard SO, et al. Comparative clinical efficacy of antimicrobial-impregnated central venous catheters. New Engl J Med 1999; 340:1-8.

Wiswell TE, Smith RM, Katz LB, Mastroianni L, Wong DY, Willms D, Heard S, et al. Bronchopulmonary segmental lavage with Surfaxin” (KL4-Surfactant) for acute respiratory distress syndrome. Am J Respir Crit Care Med 1999; 160:1188-1195.

Heard SO, Fink MP, Gamelli RL, et al. Prophylactic administration of recombinant human granulocyte colony-stimulating factor (Filgrastim) decreases the incidence of nosocomial blood-stream infections in patients with acute traumatic brain injury or cerebral hemorrhage. Crit Care Med 1998; 26:748-754.

Heard SO, Wagle M, Vijayakumar E, et al. The influence of triple-lumen central venous catheters coated with chlorhexidine and silver sulfadiazine on the incidence of catheter-related bacteremia: a randomized, controlled clinical trial. Arch Intern Med 1998: 158;81-87.

Heard SO, Toth IE, Perkins MW, Leonard JL. The role of protein kinase C in lipopolysaccharide-induced myocardial depression in guinea pigs. Shock 1994; 1:419-424.

Gluck E, Heard SO, Patel C, Mohr J, Calkins J. Use of ultra-high frequency ventilation in patients with ARDS. Chest 1993; 103:1413-1420.

Heard SO, Thomas WT, Ferrari D, Hanna D, Wong PD, Liland A, Willock MM. Analgesic effect of intraarticular bupivacaine or morphine after arthroscopic knee surgery: a randomized, prospective, double-blind study. Anesth Analg 1992; 74:822-826.

Heard SO, Helsmoortel CM, Kent JC, Shahnarian A, Fink MP. Gastric tonometry in healthy volunteers: effect of ranitidine on calculated intramural pH. Crit Care Med 1991; 19:271-274.

▴ Back To Top
Section Menu To Top