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Current Stem Cell News
(from 
ScienceDaily.com)

Key to aging immune system: Discovery of DNA replication problem
The immune system ages and weakens with time, making the elderly prone to life-threatening infection and other maladies, and scientists have now discovered a reason why.
Sugar mimics guide stem cells toward neural fate
Many growth factors that influence the fate of embryonic stem cells must bind to sugars attached to specific receptors on the surface of the cell to work. Because the sugars are difficult to manipulate, biochemists created synthetic stand ins that helped to identify substructures recognized by a growth factor involved in neural development.
Stem cell advance may increase efficiency of tissue regeneration
A new stem-cell discovery might one day lead to a more streamlined process for obtaining stem cells, which in turn could be used in the development of replacement tissue for failing body parts, according to scientists.
Cell therapy for multiple sclerosis patients: Closer than ever?
For the first time, scientists generated induced pluripotent stem cells lines from skin samples of patients with primary progressive multiple sclerosis and further, they developed an accelerated protocol to induce these stem cells into becoming oligodendrocytes, the myelin-forming cells of the central nervous system implicated in multiple sclerosis and many other diseases.
First IPS cells created to offer human model of insulin resistance
The first iPSCs that offer a human model of insulin resistance, a key driver of type 2 diabetes, have been created by researchers. "There have been no good human cell models to study insulin resistance, but such cells can now be made with iPSCs," says a co-senior author on a new paper.
'Naïve' pluripotent human embryonic stem cells created
Embryonic stem cell (ESC) research has been hampered by the inability to transfer research and tools from mouse ESC studies to their human counterparts, in part because human ESCs are “primed” and slightly less plastic than the mouse cells. Now researchers have discovered how to manipulate and maintain human ESCs into a “naïve” or base pluripotent state similar to that of mouse ESCs without the use of any reprogramming factors.
Experiments prove 'stemness' of individual immune memory cells
Specific individual immune cells, termed 'central memory T cells,' have all the essential characteristics of adult tissue stem cells, researchers have proven for the first time. Such cells can perpetuate themselves indefinitely and generate diverse offspring that can reconstitute "tissue" function. These findings indicate that it should be possible to fully restore specific immunity to pathogens in immunocompromised patients by substitution of small numbers of these T cells.
3-D-printed tissues advance stem cell research
A tissue engineering and vascular biology expert recently won a Faculty Early Career Development Award for his work on 3D tissue printing, and its contribution of the advancement of stem cell research.
New technique maps life's effects on our DNA: Powerful single-cell technique to study environmental effects on DNA
Researchers have developed a powerful new single-cell technique to help investigate how the environment affects our development and the traits we inherit from our parents.
'Support' cells in brain play important role in Down syndrome
A group of cells in the brain has been identified by researchers who say that it plays an important role in the abnormal neuron development in Down syndrome. After developing a new model for studying the syndrome using patient-derived stem cells, the scientists also found that applying an inexpensive antibiotic to the cells appears to correct many abnormalities in the interaction between the cells and developing neurons.

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