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Current Stem Cell News

Researchers find animal model for understudied type of muscular dystrophy
An animal research model has been developed for facioscapulohumeral muscular dystrophy (FSHD) to be used for muscle regeneration research as well as studies of the effectiveness of potential therapies for FSHD.
New tool aids stem cell engineering for medical research
An online analytic tool that will speed up and enhance the process of re-engineering cells for biomedical investigation has been developed by researchers. CellNet is a free-use Internet platform that uses network biology methods to aid stem cell engineering.
Key to universal flu vaccine: Embrace the unfamiliar
Human volunteers immunized against the avian flu virus H5N1 readily developed antibodies against the stem region of the viral hemagglutinin protein. In contrast, those immunized with standard seasonal trivalent vaccines did not, instead developing most of their antibodies against the more variable head region.
Biologists reprogram skin cells to mimic rare disease
Stem cell biologists have reprogrammed skin cells from patients with a rare genetic disorder, called familial dysautonomia, into neural crest cells that mimic and display many biological features of the disease. The research expedites the creation of these precursor cells from any patient with a neural crest-related disorder, allowing scientists to study each patient’s disorder at the cellular level.
Coronary arteries hold heart-regenerating cells
Endothelial cells residing in the coronary arteries can function as cardiac stem cells to produce new heart muscle tissue, investigators have discovered. The heart has long been considered to be an organ without regenerative potential, said one expert. Recent findings, however, have demonstrated that new heart muscle cells are generated at a low rate, suggesting the presence of cardiac stem cells. The source of these cells was unknown.
Zebrafish help unravel Alzheimer's disease
New fundamental knowledge about the regulation of stem cells in the nerve tissue of zebrafish embryos results in surprising insights into neurodegenerative disease processes in the human brain. A new study identifies the molecules responsible for this process.
Tissue development 'roadmap' created to guide stem cell medicine
In a boon to stem cell research and regenerative medicine, scientists have created a computer algorithm called CellNet as a 'roadmap' for cell and tissue engineering, to ensure that cells engineered in the lab have the same favorable properties as cells in our own bodies.
New blood: Tracing the beginnings of hematopoietic stem cells
Researchers elaborate upon a crucial signaling pathway and the role of key proteins, which may help clear the way to generate HSCs from human pluripotent precursors, similar to advances with other kinds of tissue stem cells.
Cell discovery brings blood disorder cure closer
A cure for a range of blood disorders and immune diseases is in sight, according to scientists who have unraveled the mystery of stem cell generation. Found in the bone marrow and in umbilical cord blood, HSCs are critically important because they can replenish the body's supply of blood cells. Leukemia patients have been successfully treated using HSC transplants, but medical experts believe blood stem cells have the potential to be used more widely.
Clinical trial evaluates safety of stem cell transplantation in spine
A clinical trial to investigate the safety of neural stem cell transplantation in patients with chronic spinal cord injuries has been launched in the United States. Related goals of the clinical trial include evaluating the stem cell graft's survival and the effectiveness of immunosuppression drugs to prevent rejection. The researchers will also look for possible therapeutic benefits such as changes in motor and sensory function, bowel and bladder function, and pain levels.

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