Animal Medicine State-of-the-art animal facilities and maintains the highest standards of animal care and veterinary services Bioinformatics Provides help and support in storing, visualizing, and analyzing biological data Biorepository The Conquering Diseases Biorepository is a partnership between the patients being cared for by the health professionals of UMass Memorial, and the research community at the University of Massachusetts Medical School. Deep Sequencing Operates an Illumina-Solexa GA Massively Parallel Deep Sequencer Digital Light Microscopy Provides UMass and outside researchers with high-resolution, multi-mode, digital microscopic imaging and image analysis Electron Microscopy Assists investigators with services and products to advance their research needs Flow Cytometry Provides extensive cytometry services for internal and external investigators with state-of-the-art sorting and analyzing services Genomics Provides GeneChip and custom microarray services to the UMMS community. Human Embryonic Stem Cell Provides human ES cells to researchers at UMASS for investigation of biological control and therapeutic application. Imaging Cores - Advanced MRI Provides the latest magnetic resonance imaging and spectroscopy capabilities to scientists, clinicians, government and industry. Technical and clinical expertise for collaborative research is also provided.
- New England Center for Stroke Research (NECStR) Develop imaging technology & medical devices for minimally invasive treatment of cerebrovascular pathologies & brain ischemia. A neuroradiology facility that offers the latest technology in image guided intervention.
- Small Animal Imaging With both the Bioscan NanoSPECT/CT and the Philips Mosaic PET small animal cameras, UMMS has the latest equipment for imaging radioactive contrast agents labeled with SPECT radionuclides such as 99mTc, 111In ,123I and PET radionuclides such as 18F, 64Cu, 68Ga, to follow the biodistributions in mice, rats, rabbits, cats, marmoset monkeys and other small animals of proteins, peptides, oligomers, nanoparticles, and other biomarkers of interest.
- Live Animal Imaging Services The Xenogen® IVIS imaging system allows detection of light-emitting cells within a living organism. The imaging system is currently being used for in vivo studies to monitor tumor development and progression, and additional studies to identify the presence of pathogenic microorganisms within mice.
Machine Shop Specializes in design, manufacture, and repair of biomedical lab equipment.
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Molecular Biology MBCL Provides DNA fragment analysis, Genotyping and SPR services.
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Morphology A DERC (Diabetes and Endocrinology Research Center) core facility that is a state-of the-art, fully equipped histology lab.
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Oligonucleotide Provides discounted DNA and RNA oligonucleotides and siRNA duplexes.
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Peptide Provides custom peptide synthesis, peptide chromatography, amino acid analysis and peptide conjugation.
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Proteomic and Mass Spectometry Cores - Proteomic Fractionation state-of-the-art proteomics laboratory that serves both UMass and external investigators in their proteomic fractionation needs. The focus of the lab is the reproducible and quantitative analysis of complex protein mixtures derived from whole organisms, tissues, cells, sub-cellular fractions or partially purified mixtures.
- Proteomics & Mass Spec Shrewsbury Equipped with the latest instrumentation for protein/peptide mass spectral analysis Specializes in Proteomic Mass Spectometry services utilizing MALDI MS and MS/MS Protein Idenfications.
- Proteomic & Mass Spectometry Worcester serves both UMass and external investigators in their proteomic fractionation needs. The focus of the lab is the reproducible and quantitative analysis of complex protein mixtures derived from whole organisms, tissues, cells, sub-cellular fractions or partially purified mixtures.
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Research Core Administration Provides financial support for the 35+ revenue-based research cores.
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RNAi Distributes clones from the Open Biosystems human and mouse shRNAmir retroviral libraries to UMMS researchers.
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Small Molecule Screening Assists researchers in developing high-throughput (HT) screening assays, performs HT screens of chemical libraries to identify new small molecules that can be used to probebiological processes.
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Tissue Culture Facility Provides a variety of cell culture support services, including programmed cell freezing, cell transfection and cloning, cell expansion, and liquid nitrogen storages and many other services. The Custom Media Center offers custom-made media and plates for microbiological and tissue culture research at very competitive pricing.
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Tissue Culture and Enzyme Freezer Supply TCEFS Supplies tissue culture products and/or fetal bovine and other sera from Atlas Biologicals, Gemini Bioproducts, HyClone, Invitrogen/GIBCO, MediaTech, and Sigma. In addition, the Enzyme Freezer Program supplies polymerases, restriction and modifying enzymes, DNA purification kits, PCR kits, and a host of other molecular biology products, from all major vendors. TCEFS offers the best discounts on campus and free shipping on all products.
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Transgenic Animal Modeling Produces genetically-altered mice for the UMMS research community.
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UMASS Cancer Center Tissue Bank engages in dynamic tissue collection,annotation, storage and distribution service, collecting fresh tissue samples for rapid processing/snap freezing immediately after surgery.
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UMASS Mouse Phenotyping Center (UMPC) is designed to provide the scientific community with sophisticated and standardized experimental tools for the purpose of investigating transgenic mouse models and understanding obesity, diabetes and its complications.
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Viral Vector Core VVC of the Gene Therapy Center uses cutting-edge technologies to create and produce a variety of high quality viral vectors. The goal of the VVC is to provide investigators at UMMS with the most suitable and efficient gene transfer vectors for their research applications.
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Veterinary Pathology Services Provides academically-oriented consultation time and scientific collaboration with an expert veterinary pathologist with expertise in mouse pathology and embryology.
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X-Ray Crystallography Provides centralized facilities andresources for conducting research, advanced teaching, and comprehensive data processing.
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| XL-I Analytical Ultracentrifuge A state-of-the-art instrument that facilitates rigorous characterization of the solution state behavior of macromolecules. |