Facilities of NECStR
The New England Center for Stroke Research (NECStR) is combined with the Advanced MR Imaging Center (AMRIC) to optimize image guided intervention with functional imaging, and together form a contiguous research space of 7,520 square feet. The primary feature of this center is a state-of-the-art angiography suite separated by a radiofrequency insulation door that leads to a 3-Tesla whole body magnet. Currently, the combination of flat panel angiography with 3T MRI makes this center unique in the world. The key details of this facility are listed below.
The angiosurgical suite dedicated to preclinical research (876 sq ft) is home to the latest flat panel detector x-ray system available today (Allura FD20 R3, Philips Medical Systems, Best, the Netherlands), which offers both cardiac and vascular imaging packages, 3-dimensional reconstruction angiography (3DRA), X-per™ cone beam computed tomography, motor driven tilt table, and various software prototypes that are not yet available for clinical use. Vascular analysis software is available with the ViewForum system. The angiosurgical suite is fully equipped for aseptic surgical procedures, including medical gases, physiological monitoring, scrub room, OR lights, surgical camera, power injectors and audiovisual equipment for procedure documentation (Berchtold, Charleston, SC). Adjacent to the angiosurgical suite is an animal surgical prep and recovery room (134 sq ft). The center also incorporates a chemistry and hemodynamics laboratories for bench-top, in vitro studies totaling 684 sq ft. There is 509 sq ft of ancillary space for microscopy, device and instrument preparation, storage and miscellaneous (locker room with showers for staff, etc). Office space for the Directors, postdoctoral and medical fellows, and graduate students totals 624 sq ft both within the center and the nearby medical school.
The Chemistry & Hemodynamics Labs are equipped with 1) an AirSentry laminar flow fume hood, 2) an ultrasonic heated cleaner, 3) a Harvery MC10 sterilizer, 4) a CompuFlow 1000 MR (Shelly Medical Imaging, Toronto, Canada) programmable cardiac pulse duplicator that drives the mock circulation flow loops, 5) a Prodigy Plus rapid prototyping system (Stratasys, Eden Prarie MN) for construction of patient specific vascular replicas, 6) a high-accuracy pressure measurement system for physiological flows (Validyne, Northridge, CA), 7) an upright microscope with an automated stage, CCD camera, and fluorescence capability (Olympus AX90, Center Valley, PA), 8) Transonic ultrasound flowmeters (Transonic Systems, Ithaca NY), 9) Dewetron data acquisition/signal conditioning system (Dewetron, Charlestown RI) 10) a texture analyzer for baseline clot characterization (Texture Technologies, Hamilton MA), 11) a Revco -86 freezer, and 12) a diamond Buehler® Isomet Low Speed Saw (Buehler; Lake Bluff, Illinois) for specialized sectioning of stented vessel specimens.