2016 RESEARCH

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Top Story: New gene variants present in 3 percent of all ALS patients

Top Story: New gene variants present in 3 percent of all ALS patients

John Landers, PhD, led a team of more than 80 scientists who found that variations in a gene with multiple functions in neurons are present in approximately 3 percent of all cases of ALS in North American and European populations, both sporadic and familial.

Top Story: UMMS receives $17.3 million to oversee manufacturing of HIV vaccine

Top Story: UMMS receives $17.3 million to oversee manufacturing of HIV vaccine

Shan Lu, MD, PhD, has received $17.3 million from the National Institute of Allergy and Infectious Diseases to develop and produce an optimized HIV vaccine to be used in Phase II human clinical trials.

Top Story: Viral infection during pregnancy causes autism-like behaviors in mice by triggering key immune reaction

Top Story: Viral infection during pregnancy causes autism-like behaviors in mice by triggering key immune reaction

A new study found that activation of a particular immune response in pregnant mice alters the brain structure of the mouse offspring and causes behavioral changes reminiscent of those observed in humans with autism. The research was published in Science. Jun Huh, PhD, is a corresponding author.

Top Story: UMMS researchers discover novel link between immune system, social behavior

Top Story: UMMS researchers discover novel link between immune system, social behavior

Vladimir Litvak, PhD, and colleagues made a startling discovery that immune system signaling can directly affect social behavior. Published in Nature, these findings could have great implications for neurological diseases such as autism-spectrum disorders and schizophrenia.

Study co-authored by Jean King finds early life exposure to social stress changes brain connectivity

Study co-authored by Jean King finds early life exposure to social stress changes brain connectivity

Scientists at UMass Medical School and the Cummings School of Veterinary Medicine at Tufts University found that exposure to social stressors early in life can change active portions of the brain linked to social behavior, stress, emotion and depression. The study, published in Behavioural Brain Research, was co-authored by Jean King, PhD.

GSN receives $2.1M grant to expand primary care in Worcester County

GSN receives $2.1M grant to expand primary care in Worcester County

With a three-year, $2.1 million grant, the GSN is launching the Central Massachusetts Advanced Nursing Education Academic-Practice Partnership to better prepare advanced practice nurses to work in underserved communities. 

Lancet paper reports on success of bionic pancreas system developed at BU, tested at UMMS

Lancet paper reports on success of bionic pancreas system developed at BU, tested at UMMS

The bionic pancreas system developed by Boston University investigators and tested at four academic medical centers, including UMass Medical School, proved better than either conventional or sensor-augmented insulin pump therapy, according to a new report of a clinical trial published in The Lancet. David M. Harlan, MD, oversaw the clinical trial at UMMS and is a co-author on the new paper. 

Massachusetts selected to partner in biopharmaceutical manufacturing innovation

Massachusetts selected to partner in biopharmaceutical manufacturing innovation

The Commonwealth of Massachusetts has been named a partner in the nation’s first manufacturing innovation institute in biopharmaceutical manufacturing, and UMass Medical School is one of five universities supporting the effort. 

UMMS PhD candidate receives Charles E. Gibbs Leadership Prize

UMMS PhD candidate receives Charles E. Gibbs Leadership Prize

PhD candidate Aimee Kroll-Desrosiers was awarded the 2016 Charles E. Gibbs Leadership Prize by Women’s Health Issues for research that examined opioid use during pregnancy by women veterans.

Ragunath Singaravelu named Gilead Fellow of the Life Sciences Research Foundation

Ragunath Singaravelu named Gilead Fellow of the Life Sciences Research Foundation

Ragunath Singaravelu, PhD, a postdoc in the lab of Katherine Fitzgerald, PhD, has been named a Gilead Fellow of the Life Sciences Research Foundation. He will use the three-year grant to consider whether long noncoding RNAs act as major regulators of innate immunity, fine-tuning gene expression relevant to the immune response to cytosolic surveillance of DNA.

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