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Bacterial Genetics and Pathogenesis
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Section: Publications

Christopher Sassetti, Ph.D.

Academic Role: Assistant Professor

Faculty Appointment(s) In:
   Molecular Genetics and Microbiology

Other Affiliation(s):
   Center for AIDS Research

Publications

Pandey, A.K., and Sassetti, C.M.  "Mycobacterial persistence requires the utilization of host cholesterol"   Proc. Nat. Acad. Sci. 2008; In Press

Yang, Y., Yin, C., Pandey, A.K., Abbott,D., Sassetti, C.M., Kelliher, M.A.  NOD2 pathway activation by MDP or Mycobacterium tuberculosis infection involves the stable polyubiquitination of Rip2  J. Biol. Chem.  2007; 282: 36223 - 36229

Sassetti, C.M. and  Rubin, E.J..   The open book of infectious diseases.  Nature Medicine. 13: 279-280. (2007)

Joshi, S. M., Pandey, A.K., Capite, N., Fortune, S.M., Rubin, E.J., and Sassetti, C.M.  Characterization of mycobacterial virulence genes through genetic interaction mapping. Proc. Nat. Acad. Sci.  103:11760-11765. (2006).

Fortune S.M, Jaeger A., Chase M.R, Sarracino, D.A, Sassetti C.M, Sherman D.R., Bloom B.R. and Rubin E.J. Mutually-dependent secretion of proteins required for mycobacterial virulence. Proc. Nat. Acad. Sci.  102:10676-81. (2005).

Rengarajan,J., Sassetti, C. M., Naroditskaya, V., Sloutsky, A., Bloom, B.R. and Rubin, E. J..   The folate pathway is a target for resistance to the drug para-aminosalicylic acid (PAS) in mycobacteria. Molecular Microbiology 53:275-282 (2004)

Sassetti, C. M. and Rubin, E. J.  Genetic requirements for mycobacterial survival during infection.  Proc. Nat. Acad. Sci. 100:12989-12994 (2003)

Sassetti, C. M., Boyd, D. H. and Rubin, E. J. Genes required for mycobacterial growth defined by high density mutagenesis.  Molecular Microbiology. 48: 77-84.  (2003)

Sassetti, C. M., Boyd, D. H. and Rubin, E. J. Comprehensive identification of conditionally essential genes in mycobacteria. Proc. Nat. Acad. Sci. 98: 12712-12717. (2001)

 


Office: S6 141
Phone: 508 856 3678
E-mail: Christopher.Sassetti@umassmed.edu
Keywords: Microbial Pathogenesis, Genomics, Tuberculosis, Infectious Disease, Genetics

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