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In section: Morningside Graduate School of Biomedical Sciences
In subsection: Blog
Perturbations in normal gene expression arising from defects in genome organization can lead to cellular dysfunctions linked to aging and various disease states. The mammalian genome is generally
Last modified: Aug 19, 2021
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In section: Morningside Graduate School of Biomedical Sciences
In subsection: Blog
The goal of this project is fluorescently visualize ATP release and extracellular accumulation at the surface of stimulated microglia. The development of this innovative technology has the
Last modified: Sep 08, 2021
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In section: Morningside Graduate School of Biomedical Sciences
In subsection: Blog
Cell death is a normal part of cellular function, and this important behavior can occur through several different mechanisms. One form of cell death—pyroptosis—is characterized by the dying cells
Last modified: Oct 06, 2021
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In section: Morningside Graduate School of Biomedical Sciences
In subsection: Blog
The central nervous system is susceptible to many environmental insults and like many organs can be affected by alcohol. Alcohol impacts the brain in a variety of ways including short-term
Last modified: Dec 16, 2021
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In section: Morningside Graduate School of Biomedical Sciences
In subsection: Blog
Hepatitis C virus (HCV), a pathogen that infects over 150 million people worldwide, is the leading cause of chronic hepatitis, liver cirrhosis and hepatocellular carcinoma. HCV is a genetically
Last modified: Dec 16, 2021
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In section: Morningside Graduate School of Biomedical Sciences
In subsection: Blog
Breast Cancer is the most frequent malignancy diagnosed in women in the United States and the second leading cause of cancer related mortality in women. Metastasis to distant organs continues to
Last modified: Dec 16, 2021
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In section: Morningside Graduate School of Biomedical Sciences
In subsection: Blog
Promising emerging therapies for Huntington's disease target mutant but not wild-type huntingtin mRNA with small interfering RNAs. However, our limited understanding of allele-specific mRNA
Last modified: Dec 20, 2023
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In section: Morningside Graduate School of Biomedical Sciences
In subsection: Blog
CRISPR-Cas9 technology has profoundly advanced genetic research and gene therapy by enabling rapid, precise, and programmable genome editing to study gene function or correct mutations in cells
Last modified: Sep 05, 2023
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In section: Morningside Graduate School of Biomedical Sciences
In subsection: Blog
The overarching goal of this project is to understand how non-apoptotic cell death is activated by the DNA damage response (DDR). In response to genomic insult, the DDR activates DNA repair and
Last modified: Feb 01, 2024
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In section: Morningside Graduate School of Biomedical Sciences
In subsection: Blog
Abstract Pneumonia is the leading cause of infection-related deaths worldwide, a fact that is set to rise exponentially with the SARS-CoV2 pandemic. Recovery from pneumonia requires both clearance
Last modified: Mar 22, 2023