Research in Endocrinology & Metabolism

NIH Training Grant

For more than three decades, the Endocrinology Program at UMass has successfully competed for an NIH-Sponsored Training Grant. The award is intended to train both clinical (M.D.) and basic (Ph.D.) scientists whose research and/or academic patient care careers will improve the care and outcome of endocrine diseases and diabetes mellitus.

Our program offers classical endocrinology and diabetes research opportunities, but in addition seeks to extend the breadth of the training offered to encompass cutting edge concepts, technologies, and programs that are clinical/translational in nature. These areas are emphasized: immunology of diabetes and islet transplantation, neuroendocrinology, cell signaling, Type 2 Diabetes and endocrinology of the fat cell, and developmental study of bone. In addition, we study mechanisms of gene silencing.

We support 1 MD and 2 PhD trainees annually for 2-3 years each. MD trainees have access to graduate school coursework in molecular and cellular biology, and PhD trainees attend special seminars to enhance their knowledge of the translation of basic research to the clinic.

An interdepartmental program in molecular medicine has been established, giving trainees the opportunity to learn and apply modern molecular biological techniques to basic and clinical problems. Core facilities include laboratories for providing amino acid analysis and sequences of proteins, peptide synthesis and oligonucleotide synthesis, steroid receptor assays, tissue morphology, tissue culture, hormone immunoassays, transgenic core, and production of monoclonal antibodies. These core facilities are supported by the NIH's Diabetes Endocrinology Research Center (DERC).

 

Research at UMMS has already led to exciting advances in the treatment of disease and injuries, and the future promises many more health care delivery breakthroughs. And while patient application is the ultimate goal of UMMS research, economic spinoff to the surrounding region is a significant and important byproduct.