Featured Studies

Study looking to enroll people who recently lost weight!

(Docket # H-00001808)

Even highly motivated individuals find it difficult to keep weight off after they have lost it. The purpose of the study is to understand brain changes that accompany participation in wellness programs for keeping weight off. We will use MRI scans to study brain function in men and women 25-55 years old who have lost weight in the last year without surgery. Participants will be assigned to one of two programs to help them maintain weight loss and will be compensated for their time. Our goal is to gain a better understanding of the brain changes that lead to long-term success in keeping weight off, in the hope that this knowledge will assist in the development of improved treatments. To find out if you may be eligible call us at 508-856-1225 or email keepitoff@umassmed.edu to find out more information.

GeneSight Clinical Study (Docket # H-00004690)

The study is trying to see if a genetic test is helpful in guiding clinicians’ selection of medications for depression.  You might be eligible to participate in this study if:

  • You are trying or have recently tried a psychiatric medication, and
  • Your symptoms of depression are not improving despite at least 6 weeks on the treatment you are receiving, and/or
  • You are unable to tolerate the medication and have discontinued it.

If you would like more information, please call Jessica 774-455-4045.

Research study seeking healthy volunteers to complete one MRI scan
(Docket # H-00001036)

Healthy volunteers are invited to participate in an MRI research study to assess potential brain changes associated with antipsychotic treatment. This study will provide information regarding the potential effects on brain structure, function, and connectivity of antipsychotic maintenance treatment in patients with mood disorders. Study participation will entail a commitment of one study visit, and one MRI scan. Patients must be: 18 to 85 years of age; healthy without mood symptoms; not be pregnant. Compensation provided. Contact Chelsea Kosma @ 508-856-5312.


Vitamin D supplementation for Bipolar Depression (Docket # H-800)

A new research study at UMass Medical Center is evaluating Vitamin D supplementation for bipolar depression. The goal of this research is to see if Vitamin D supplementation in people with bipolar disorder is associated with improved mood, in particular less depression. The study includes questions about mood, Vitamin D level monitoring, and Vitamin D supplementation or placebo. Participants stay on their current medication regimen. This study involves seven assessments over the course of 12 weeks, and participants are compensated for their time. In order to be eligible, patients must be: 25 years old or older; diagnosed with bipolar disorder; currently feeling down, sad, or depressed; and have low Vitamin D levels (evaluated at first study visit). For more information please contact Jessica Penny (508-334-7352) or Dr. Wendy Marsh (508-856-5071)

Research study looking for pregnant women to test a website for healthy pregnancy weight gain (IRB docket #H00001690)

We are conducting a research study to get pregnant women’s feedback on our ideas for a website to help women gain a healthy amount of weight during pregnancy. During a study visit, participants will test out a website and complete a short questionnaire. The study will take about 1-1.5 hours total. Compensation is provided. To learn more about the study, please email us at babystudy@umassmed.edu or call Sherry at (774) 455-3858.

How can physicians help patients lose weight? (Docket # H-00002798)

Have you seen a primary care provider in Worcester County in the last six months? Do you think you need to lose some weight, and would be willing to complete a survey on how physicians can help patients lose weight? This survey will be completed by mail, and questions will be about your beliefs about weight and weight loss, and resources and aids for weight loss. Call 508.856.5691 to see if you would be eligible for this research study. Tell a friend. Compensation is provided. Call Linda at 508.856.5691 or email weightlossstudy@umassmed.edu for more information.