CFAR Members
CFAR Members |
Department, Division or Program Affiliation | Research Interests |
Jeroan Allison | Department of Quantitative Health Sciences | Behavioral interventions regarding adherence to medication in chronic disease patients |
Leslie Berg | Department of Pathology | T Lymphocyte Development and Activation |
Diane Blake | Department of Pediatrics | Pediatric Adolescents |
Dan Bolon | Department of Biochemistry and Molecular Pharmacology |
Molecular Mechanisms of Adaptation in Biology and Disease |
Victor Boyartchuk | Department of Microbiology and Physiological Systems, Program in Gene Function and Expression | Studies of the Genetic Factors Controlling Susceptibility to Infectious Diseases using Animal Model Systems |
Carol Bova | Tan Chingfen Graduate School of Nursing | Emerging Primary Care Needs; primary care needs of women with HIV infection; interaction of substance abuse, mental illness and adherence behaviors; HCV treatment among HIV-infected adults |
Edward Boyer | Department of Emergency Medicine | HIV Prevention using Artificial Intelligence and Mobile Technology, Mobile Technology approaches to improving HAART Adherence in HIV+ Drug Users |
Abraham Brass | Department of Microbiology and Physiologic Systems | Use of functional genomics, proteomics, molecular genetics and biochemical approaches to study host-viral interactions |
Michael Brehm | Department of Molecular Medicine | Host immune responses to viral infections |
Doreen Brettler | Department of Medicine, Division of Hematology & Oncology | Director, New England Hemophilia and Thrombosis Center |
Anthony Carruthers | Department of Biochemistry & Molecular Pharmacology | Carrier-mediated transport |
Lucio Castilla | Program in Molecular Medicine, Program Gene Function & Expression | Genetics of Leukemia, Mouse Models |
Francis Chan | Department of Pathology | The Role of Programmed Cell Death in Immune Functions & Diseases |
Sarah Cheeseman | Department of Medicine, Division of Infectious Diseases & Immunology | Antiretroviral Therapy Clinical Trials, HIV in Pregnancy, Issues in Perinatally Infected Adolescents & Young Adults |
Jason Chen | Department of Medicine | Cell cycle checkpoints, genomic instability, and apoptosis in cells expressing papillomavirus oncogenes |
Paul Clapham, Director, CFAR Developmental Core, Co-Director, CFAR Experimental Virology Core | Program in Molecular Medicine | The HIV envelope: Biology, Receptors and Cellular Tropism |
Michael Czech | Program in Molecular Medicine | RNAi-based Therapeutic Strategies for Inflammatory and Metabolic Diseases |
Jennifer Daly | Department of Medicine, Division of Infectious Diseases | Clinical research in antibiotics, immune reconstitution in HIV patients, medical services utilization in HIV patients |
Raul Davaro | Department of Medicine, Division of Infectious Diseases & Immunology | Antiretroviral Therapy Adherence Strategies, HIV care management, Prevention and Management of Opportunistic Infections |
Roger Davis | Program in Molecular Medicine | Mechanisms by which Growth Factors regulate Cellular Proliferation |
Ronald Desrosiers | New England Primate Research Center (NEPRC), Harvard Medical School |
Molecular Mechanisms underlying Viral Pathogenesis through the use of Monkey Models of Human Viral Diseases |
Maria Jose Duenas-Decamp | Program in Molecular Medicine | HIV neutralization and tropism; tropism of Hematopoietic Stem Cells |
Richard Ellison | Department of Medicine, Division of Infectious Diseases & Immunology | Identification and Treatment of Nosocomial Infections |
Francis Ennis | Department of Medicine, Center for Infectious Disease & Vaccine Research | Immune Response of Host to Virus Infection |
David Evans | New England Primate Research Center, Harvard University | understanding mechanisms of protective immunity and immune evasion using simian immunodeficiency virus (SIV) infection as an animal model for AIDS |
Michael Farzan | New England Primate Research Center, Harvard University | HIV-1 entry into target cells, receptors or HIV-1 and other viruses |
Robert Finberg | Department of Medicine, Division of Infectious Diseases & Immunology | Host-microbial Interactions |
Katherine Fitzgerald | Department of Medicine, Division of Infectious Diseases and Immunology | Sensing and Signaling in the Innate Immune Response |
Terence Flotte | Dean, Provost and Executive Deputy Chancellor of UMass Chan Medical School, Department of Pediatrics, Department of Microbiology and Physiological Systems, Department of Biochemistry and Molecular Pharmacology, Clinical and Population Health | alpha-1 antitrypsin (AAT) deficiency, in which lung disease develops as a consequence of loss of function and liver disease develops as a consequence of a accumulation of the mutant Pi-Z form of the AAT protein |
Lisa Fortuna | Department of Psychiatry | Latino mental health services research, substance abuse and dual diagnoses in adolescence |
Andrea Foulkes | Department of Biostatistics, Public Health, UMass Amherst, MA | Biostatistics and Statistical Genetics |
Michaela Gack | New England Primate Research Center, Harvard University | IFN-mediated Innate Immune Responses against viral infection |
Uri Galili | Department of Medicine | |
Donna Gallagher | New England AIDS Education and Training Center, ForHealth Consulting, Office of Global Health | Health Interventions and Policies |
Ricardo Gazzinelli | Department of Medicine, Division of Infectious Diseases & Immunology | Innate immune mechanisms and pathogenesis of protozoan infections; development of vaccines against these infections |
Rachel Gerstein | Department of Microbiology and Physiological Systems | Developmental regulations of V(D)J Recombinant and B Cell Development |
Laura Gibson | Department of Medicine, Division of Infectious Diseases & Immunology | Human T cell responses to cytomegalovirus (CMV) in children and transplant recipients |
Douglas Golenbock | Department of Medicine, Division of Infectious Diseases & Immunology | Toll Receptors, Sepsis and Malaria |
Phil Gona | Department of Quantitative Health Sciences | Statistical and Epidemiological research in HIV/AIDS, especially opportunistic infections; global health issues of HIV/AIDS surveillance and clinical research; clinical trials for new drug development; survival and longitudinal analyses |
Heinrich Gottlinger | Program in Molecular Medicine, Program in Gene Function and Expression | Molecular Biology of HIV-1 |
Michael Green | Program in Molecular Medicine, Program in Gene Function and Expression | Eukaryotic Gene Regulation and CancerMolecular Biology |
Thomas Greenough, Co-Director, CFAR Translational Medicine (Clinical) Core | Department of Medicine, Division of Infectious Diseases & Immunology, Pediatrics | Pathogenesis of HIV-1 |
Dale Greiner | Program in Molecular Medicine |
Pathogenesis of Type 1 Diabetes; |
Deborah Harmon-Hines | Department of Cell Biology | Education Outreach and Anatomy for Medical Education |
Joonsoo Kang | Department of Pathology | T Cell Lineage Commitment |
Paul Kaufman | Department of Gene Function and Expression | Chromosome structure and dynamics |
Michelle Kelliher | Department of Cancer Biology | Apoptosis and Cancer |
Catarina Kiefe | Department of Quantitative Health Science | Leadership in clinical and translational research, Biostatistics, Health Policy |
Ellen Kittler, Coordinator, CFAR Core Lab Services, Co-Director, CFAR Molecular Biology Core | Program in Molecular Medicine | Genomic archeology of markers for disease and disease susceptibility |
Hardy Kornfeld | Department of Medicine, Division of Pulmonary, Allergy & Critical Care Medicine | Host Defense Against Bacterial and Viral Respiratory Pathogens with Emphasis on Tuberculosis |
Andrei Korostelev | Department of Biochemistry and Molecular Pharmacology | Structural understanding of the mechanisms of translation regulation during stress and disease; the molecular basis of expression of Gag and other proteins of cellular and viral origins. |
Timothy Kowalik | Department of Microbiology and Physiological Systems | Cell Activation and DNA Viruses |
Evelyn Kurt-Jones | Department of Medicine, Division of Infectious Diseases & Immunology | Signaling by Receptors on Monocytes and Macrophages that Mediate the Innate Immune Response to Bacterial and Viral Infection |
David Lapointe | Department of Cell Biology | Bioinformatics, Gene Expression, Systems Biology |
Stuart Levitz | Department of Medicine, Division of Infectious Diseases & Immunology; Department of Microbiology and Physiological Systems | Pathogenesis of opportunistic fungal pathogens and vaccine development against them |
Shan Lu, CFAR Co-Director | Department of Medicine | Immunogenicity of Protein Antigens, HIV Vaccine Research and Development |
Jeremy Luban, CFAR Co-Director | Program in Molecular Medicine | Genetic and biochemical techniques to identify host cell factors that contribute to viral replication, pathogenesis and human immunity |
Katherine Luzuriaga, Director, CFAR Translational Medicine (Clinical) Core |
Department of Pediatrics, Division of Infectious Diseases & Immunology, Rheumatology | Virus-Host Dynamics in Persistent Viral Infections |
Pranoti Mandrekar | Department of Medicine, Division of Gastroenterology | Signaling Mechanisms in Liver Inflammation |
William Marshall | Department of Medicine, Division of Infectious Diseases & Immunology | Mechanisms that Viruses Employ to Evade Innate Immunity |
Anuja Mathew | Department of Medicine, Division of Infectious Diseases & Immunology |
Assessment of novel humanized mouse models to study immune responses to viral infections |
C. Robert Matthews | Department of Biochemistry and Molecular Pharmacology | Solving the Protein Folding Problem |
Craig Mello | Program in Molecular Medicine, RNA Therapeutics Institute | Regulation of gene expression during early embryogeneis in C. elegans |
John Mordes | Department of Medicine, Division of Endocrinology & Metabolism | Basic and clinical research in type 1 diabetes |
Ann Moormann | Department of Pediatrics,Division of Infectious Diseases & Immunology, Rheumatology | Understanding the Development and Maintenance of Adaptive Immunity to Infectious Diseases in Pediatric Populations, Especially During Co-Infection with Different Pathogens |
Trudy Morrison | Department of Microbiology and Physiological Systems | Mechanisms of Paramyxovirus Membrane Fusion, Assembly of Paramyxoviruses, Development of Virus Vaccines |
Mary Munson | Department of Biochemistry and Molecular Pharmacology | Mechanisms for the spatial and temporal regulation of vesicular trafficking and membrane fusion;the molecular bases of endo- and exocytosis of various cargoes, including critical HIV proteins |
Peter Newburger | Department of Pediatrics, Division of Hematology & Oncology | Neutrophil Function and Gene Expression |
Reeta Prusty Rao | Department of Biology and Biotechnology, Worcester Polytechnic Institute | Fungal pathogenesis: fungal virulence factors; host immunesystem modifiers; secondary metbolite signals. High throughput screens for compounds against C. albicans |
Kenneth Rock | Department of Pathology |
Mechanisms to Control Display of ForeignAntigens to Immune System |
Ann Rothstein | Department of Medicine, Division of Infectious Diseases & Immunology | T and B lymphocyte activation, function, longevity and apoptosis |
Christopher Sassetti | Department of Microbiology and Physiological Systems | Pathogenesis of Tuberculosis |
Celia Schiffer, Director CFAR Program, Director, CFAR Administrative and Development Cores | Biochemistry & Molecular Pharmacology | Structural Basis for Molecular Recognition in HIV Protease |
Liisa Selin | Department of Pathology | Mechanisms of Viral Immunology |
Ann Sheehy | Biology Department, College of the Holy Cross, Worcester, MA | APOBEC3G Investigation and Resistance to viral Infection |
Neal Silverman | Department of Medicine, Division of Infectious Diseases & Immunology | Immune Signaling Pathways |
Mohan Somasundaran, Director, CFAR Experimental Virology Core | Department of Pediatrics | Viral and Host Factors |
Janet Stavnezer | Department of Microbiology and Physiological Systems | Mechanism and Regulation of Antibody Class Switch Recombination |
Lawrence Stern | Department of Pathology | Molecular Recognition in the Immune System |
Caterina Strambio De Castillia | Program in Molecular Medicine | Understanding retroviral-host interactions; viral particle tracking and motion analysis; building a bioinformatics framework to support the examination of retroviral particle movement |
John Sullivan | Office of Research | Epstein-Barr Virus [EBV] and Human Immunodeficiency Virus [HIV] |
Susan Swain | Department of Pathology | T cell mechanisms to control and eradicate viral infections |
Gyongyi Szabo | Department of Medicine, Division of Gastroenterology | Immune Alterations induced by Acute Alcohol Consumption |
Eva Szomolanyi-Tsuda | Department of Pathology | Interactions of Viral Gene Products and Host Immune Systems |
Jennifer Wang | Department of Medicine, Division of Infectious Diseases & Immunology | Virus interactions with toll-like receptors |
Shixia Wang | Department of Medicine | Novel Designs of HIV-1 MPER Antigen to Elicit gp41-mediated Neutralizing Antibodies |
Raymond Welsh | Department of Pathology | Viral Immunology and Pathogenesis |
Zhiping Weng | Department of Biochemistry and Molecular Pharmacology, Program in Bioinformatics and Integrative Biology | Molecular mechanisms of gene regulation, Protein docking, Small silencing RNAs |
Mireya Wessolossky | Department of Medicine, Division of Infectious Diseases & Immunology | Clinical research in HIV/AIDS, neurocognitive issues in HIV, HCV co-infection, anal displasia |
Robert Woodland | Department of Microbiology and Physiological Systems | Regulation of B Cell Survival Control of Virus Expression by Lymphocyte Activators |
Zuoshang Xu | Department of Biochemistry & Molecular Pharmacology | Mechanism and Therapy of Neurodegenerative Diseases |
Maria Zapp, Director, CFAR Molecular Biology Core | Program in Molecular Medicine | Regulation of Retroviral and Cellular mRNA Transport |