The Department of Biochemistry and Molecular Pharmacology strives to bring a molecular perspective to problems in biology and medicine. The Department currently has 23 faculty who, with over 200 postdoctoral fellows, research associates, graduate students and staff, conduct research on a wide variety of topics. Research topics include: mechanisms of protein folding, protein dynamics and assembly, bio-organic chemistry, RNA biology, structural biology, molecular modeling, molecular pharmacology, mechanisms of epigenetic inheritance, drug discovery, developmental biology, DNA repair and recombination, protein translocation mechanisms, gene expression, neuroscience and membrane biology. Collaborations with colleagues in other basic science and clinical departments enrich the possibilities for translating discoveries in basic science to clinical applications in our hospital. And the recently initiated development of companion programs in RNA Therapeutics, Stem Cell Biology and Gene Therapy portend new opportunities in translational research for our faculty and students.
The BMP Department occupies two floors in a nine-floor 350,000 square-foot research building designed to integrate research and teaching in an exciting, state-of-the-art environment. Departmental facilities, including x-ray spectrometry, NMR spectroscopy, small molecule screening and both time-resolved and fluorescence correlation spectroscopy, are complemented by proteomics, deep sequencing, imaging, cell sorting, electron microscopy and a transgenic mouse facilities supported by the Medical School. Research is supported by both public and private agencies including the National Institutes of Health, National Science Foundation, Howard Hughes Medical Institute, Keck Foundation, Burroughs Wellcome Fund, American Heart Association, American Cancer Society, American Diabetes Association, Goldhirsh Foundation, National Alliance for Autism Research, March of Dimes, Juvenile Diabetes Research Foundation, Amyotrophic Lateral Sclerosis Association, and the Human Frontiers in Science Program. The departmental research programs also receive funding from private companies.
The faculty and staff in BMP are committed to providing a stimulating environment that makes biomedical research an exciting educational endeavor for all students and post-doctoral researchers.