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Biochemistry and Molecular Biotechnology Department

Our mission is to illuminate the molecular mechanisms that govern basic biological processes, with an emphasis on integrative strategies to reveal fundamental mechanistic insights and develop new therapeutic paradigms empowered by a collaborative, diverse & inclusive community.

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BMB Blog Posts

Jul 31, 2024

Celebrating RNA Day with Dr. Thoru Pederson

Join us (the BMB) in celebrating RNA Day by learning more about the innovative bioengineering by the Pederson Lab.

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May 10, 2024

Dr. Brian Kelch Receives the Education Service Award, 2024

Dr. Brian Kelch received the Education Service Award in 2024! Learn more about his dedication to education in this blog post.

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Check out more of our blogs here!

Latest News

Latest BMB news as reported by the UMass Chan Communications Office

New research examines mechanisms of protein complex at basic cell biological level

January 14, 2025
PhD student among first to join UMass Chan program focused on quantitative skills

December 09, 2024
UMass Chan community invited to ponder meaning of ‘advancing together’ at art exhibit

September 25, 2024
UMass Memorial Health gift, with matching funds from UMass Foundation, to fund five new endowed chairs at UMass Chan

September 19, 2024
Convocation 2024: UMass Chan racing toward ambitious future

September 13, 2024
Morningside Graduate School of Biomedical Sciences celebrates largest class at qualifying exam ceremony

September 12, 2024
UMass Chan kicks off 2024 academic year with weeklong Convocation celebration

August 30, 2024
UMass Chan neuroscientist receives $4.1 million Transformative Research Award to study Down syndrome

July 16, 2024
UMass Chan BRIDGE Fund commits $2M in six faculty projects

July 03, 2024
Morningside Graduate School of Biomedical Sciences celebrates milestones of IMSD, PREP students

June 18, 2024
Advancing gender equity, importance of mentoring highlighted at Women’s Faculty Awards

May 24, 2024
Twenty rising faculty members graduate from Junior Faculty Development Program

May 17, 2024
Celia A. Schiffer elected to National Academy of Sciences

May 03, 2024
Mary Munson, Craig Peterson named American Association for the Advancement of Science fellows

April 18, 2024
Zhiping Weng named inaugural chair of the Department of Genomics & Computational Biology

November 03, 2023
Celebrating collaboration, UMass Chan launches ‘Advancing Together’ brand

September 06, 2023

Check out more news here!

Recent Publications

Total: 15 results

A single cell atlas of the mouse seminal vesicle

Tuesday, March 04, 2025

Author(s): Fengyun Sun,Kathleen Desevin,Yu Fu,Shanmathi Parameswaran,Jemma Mayall,Vera Rinaldi,Nils Krietenstein,Artür Manukyan,Qiangzong Yin,Carolina Galan,Chih-Hsiang Yang,Anastasia V Shindyapina,Vadim N Glady...

Source: G3 (Bethesda, Md.)
A robust fluorogenic substrate for chikungunya virus protease (nsP2) activity

Friday, February 21, 2025

Author(s): Sparsh Makhaik,Wioletta Rut,Shruti Choudhary,Tulsi Upadhyay,Chenzhou Hao,Michael Westberg,Cedric Bobst,Euna Yoo,Jasna Fejzo,Michael Z Lin,Matthew Bogyo,Paul Thompson,Marcin Drag,Jeanne A Hardy

Source: Protein science : a publication of the Protein Society
Capsid transfer of the retrotransposon Copia controls structural synaptic plasticity in Drosophila

Tuesday, February 18, 2025

Author(s): P Githure M'Angale,Adrienne Lemieux,Yumeng Liu,Shuhao Wang,Max Zinter,Gimena Alegre,Alfred Simkin,Vivian Budnik,Brian A Kelch,Travis Thomson

Source: PLoS biology
A quantitative intracellular peptide-binding assay reveals recognition determinants and context dependence of short linear motifs

Sunday, January 26, 2025

Author(s): Mythili S Subbanna,Matthew J Winters,Mihkel Örd,Norman E Davey,Peter M Pryciak

Source: The Journal of biological chemistry
Structural Analysis of Inhibitor Binding to Enterovirus-D68 3C Protease

Saturday, January 25, 2025

Author(s): Vincent N Azzolino,Ala M Shaqra,Akbar Ali,Nese Kurt Yilmaz,Celia A Schiffer

Source: Viruses
TRIM28-dependent developmental heterogeneity determines cancer susceptibility through distinct epigenetic states

Friday, January 24, 2025

Author(s): Ilaria Panzeri,Luca Fagnocchi,Stefanos Apostle,Megan Tompkins,Emily Wolfrum,Zachary Madaj,Galen Hostetter,Yanqing Liu,Kristen Schaefer,Chih-Hsiang Yang,Alexis Bergsma,Anne Drougard,Erez Dror,PERMUTE,D...

Source: Nature cancer
Controlled Inflammation Drives Neutrophil-Mediated Precision Drug Delivery in Heterogeneous Tumors

Sunday, January 12, 2025

Author(s): Yunfei Guo,Yiming Li,Jianmin Li,Haoran Cai,Kangkang Liu,Dengyi Duan,Wenyi Zhang,Gang Han,Yang Zhao

Source: Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Nucleosome Spacing Can Fine-Tune Higher Order Chromatin Assembly

Tuesday, January 07, 2025

Author(s): Lifeng Chen,M Julia Maristany,Stephen E Farr,Jinyue Luo,Bryan A Gibson,Lynda K Doolittle,Jorge R Espinosa,Jan Huertas,Sy Redding,Rosana Collepardo-Guevara,Michael K Rosen

Source: bioRxiv : the preprint server for biology
Protein Citrullination in Amyotrophic Lateral Sclerosis and Other Neurodegenerative Diseases

Monday, December 23, 2024

Author(s): Issa O Yusuf,Webb Camille,Paul R Thompson,Zuoshang Xu

Source: Journal of experimental neurology
High-throughput discovery and deep characterization of cyclin-CDK docking motifs

Monday, December 16, 2024

Author(s): Mihkel Örd,Matthew J Winters,Mythili S Subbanna,Natalia de Martin Garrido,Victoria I Cushing,Johanna Kliche,Caroline Benz,Ylva Ivarsson,Basil J Greber,Peter M Pryciak,Norman E Davey

Source: bioRxiv : the preprint server for biology
Direct delivery of Cas-embedded cytosine base editors as ribonucleoprotein complexes for efficient and accurate editing of clinically relevant targets

Monday, December 16, 2024

Author(s): Jeong Min Lee,Jing Zeng,Pengpeng Liu,My Anh Nguyen,Diego Suchenski Loustaunau,Daniel E Bauer,Nese Kurt Yilmaz,Scot A Wolfe,Celia A Schiffer

Source: Nucleic acids research
Cryo-electron tomography of eel sperm flagella reveals a molecular "minimum system" for motile cilia

Wednesday, December 11, 2024

Author(s): Jason R Schrad,Gang Fu,Whitney E Hable,Alexandra M Tayar,Kenneth Oliveira,Daniela Nicastro

Source: Molecular biology of the cell
piRNA Defense Against Endogenous Retroviruses

Wednesday, November 27, 2024

Author(s): Milky Abajorga,Leonid Yurkovetskiy,Jeremy Luban

Source: Viruses
Glucose limitation protects cancer cells from apoptosis induced by pyrimidine restriction and replication inhibition

Tuesday, November 26, 2024

Author(s): Minwoo Nam,Wenxin Xia,Abdul Hannan Mir,Alexandra Jerrett,Jessica B Spinelli,Tony T Huang,Richard Possemato

Source: Nature metabolism
The centennial of E.B. Wilson's The Cell in Development and Heredity

Thursday, November 21, 2024

Author(s): Jane Maienschein,Martin Chalfie,Thoru Pederson

Source: Molecular biology of the cell

A full list of department publications can be found here.

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Upcoming Events

Check out our upcoming seminars and events!

March 2025

FEB

APR

2025

Sun
Mon
Tue
Wed
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Fri
Sat

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James Chen
James Chen 2:00pm
4
James Chen
James Chen 11:00am
5
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No RIPS
No RIPS 4pm
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9
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Dave Shechner
Dave Shechner 12pm
13
Dave Shechner
Dave Shechner 11:00am
14
No RIPS
No RIPS 4PM
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Nick Till
Nick Till 12pm
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Nick Till
Nick Till 11am
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RIPS, Jagroop Kaur
RIPS, Jagroop Kaur 4pm
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RIPS, Samirul Bashir
RIPS, Samirul Bashir 4pm
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Today