The UMass Center for Stem Cell Biology and Regenerative Medicine has been established around the promise that lies within the application of using human stem cells for regenerative therapeutics. The center’s basic research programs focus on the cellular, molecular and biochemical composition of pluripotent cells and how they can be manipulated to understand disease mechanisms as well as provide the basis for novel dimensions to treatment. By collaborating with the RNA Therapeutics Institute and Gene Therapy centers of the Advanced Therapeutics Cluster, the Stem Cell Center anticipates developing translational research programs for cancer, juvenile diabetes, Alzheimer’s, Parkinson’s and other diseases.
Importantly, the center is poised to provide a research environment and infrastructure to facilitate scientific interactions between multi-disciplinary basic, biomedical and clinical investigators. This interaction merges the sustained excellence of the UMMS basic science faculty with the success of the four clinical research centers of excellence on the UMMS campus in the area of Cancer, Diabetes, Heart and Vascular and Musculoskeletal diseases. Ultimately the center serves as a critical translational bridge between bench discoveries in basic biomedical research and healthcare delivery.
Through its support component involving the International Stem Cell Registry and the Human Stem Cell Bank, the Center provides the research community with a single source, for comprehensive information on all published human embryonic and reprogrammed (IPS) cell lines. The bank is establishing itself as a central clearing house to verify published characteristics of the lines and to provide an independent site for storage and distribution of pluripotent human cells.
The Education & Training Program offers “state-of-the-art” background and experience in stem cell biology and technologies, facilitating development of a skilled workforce for academia as well as for the biotechnology/pharmaceutical industries.
To provide expertise, education, experience and infrastructure for the extensive investigation of stem cells. To serve research communities at UMMS, State, national and international levels by working collaboratively with basic science and clinical departments as well as for the RNA Therapeutics Institute and Gene Therapy centers to develop and translate scientific breakthroughs into novel therapeutics for clinical evaluation and treatment of patients.