PMM Graduate Student Publications (2004-2008)

(Graduate students are highlighted by bold-faced type)

Mangada, J., T. Pearson, M. B. Brehm, L. S. Wicker, L. B Peterson, L. D. Shultz, D. V. Serreze, A. A. Rossini, and D. L. Greiner. Idd loci synergize to prolong islet allograft survival induced by costimulation blockade in NOD mice. Diabetes, 58:165-173, 2009.

King, M, T. Pearson, L.D. Shultz, J. Leif, R. Bottino, M. Trucco, M.A. Atkinson, C. Wasserfall, K.C. Herold, R.T. Woodland, M.R. Schmidt, B.A. Woda, M.J. Thompson, A.A. Rossini, D.L. Greiner. A new Hu-PBL model for the study of human islet alloreactivity based on NOD-scid mice bearing a targeted mutation in the IL‑2 receptor gamma chain gene. Clin Immunol, 126:303-314, 2008

Sinha, M. and Peterson, C.L. (2008). A Rad51 presynaptic filament is sufficient to capture nucleosomal homology during recombinational repair of a DNA double strand break. Molec. Cell., 30:803-811.

Batista, P.J., Ruby, J.G., Claycomb, J.M., Chiang, R., Fahlgren, N., Kasschau, K.D., Chaves, D.A., Gu, W. Vasale, J.J., Duan, S., Conte, D. Jr., Luo, S., Schroth, G.P., Carrington, J.C., Bartel, D.P., Mello, C.C. (2008) PRG-1 and 21U-RNAs Interact to Form the piRNA Complex Required for Fertility in C. elegans. Mol Cell. 31:67-78. PMID 18571452

Burns, D.M., Richter, J.D. (2008). CPEB regulation of human cellular senescence, energy metabolism, and p53 mRNA translation. Genes Dev. 22:3449-60.

Harvey, C., Ehrhardt, A., Cellurale, C., Zhong, H., Yasuda, Davis, R. J., and Svoboda, K. (2008). A genetically-encoded fluorescent sensor of ERK activity. Proc Natl. Acad. Sci. USA 105:19264-19269 (2008).

Lipson, K.L., Ghosh, R., and Urano, F. (2008). The role of IRE1α in the degradation of insulin mRNA in pancreatic β-cells. PLoS One, 3:e1648.

Shi X, Burkart A, Nicoloro SM, Czech MP, Straubhaar J, Corvera S. (2008). Paradoxical effect of mitochondrial respiratory chain impairment on insulin signaling and glucose transport in adipose cells. J Biol Chem. 283:30658-67.

Grove CA and Walhout AJM (2008). Transcription factor functionality and transcription regulatory networks. Molecular Biosystems, 4;309-314. 

Wajapeyee N, Serra RW, Zhu X, Mahalingam M, Green MR. (2008). Oncogenic BRAF induces senescence and apoptosis through pathways mediated by the secreted protein IGFBP7. Cell 132:363-74.

Gealekman O, Burkart A, Chouinard M, Nicoloro SM, Straubhaar J, Corvera S. (2008). Enhanced angiogenesis in obesity and in response to PPARgamma activators through adipocyte VEGF and ANGPTL4 production. Am J Physiol Endocrinol Metab. 295:E1056-64.

Martinez NJ, Ow MC, Barrasa MI, Hammell M, Sequerra R, Doucette-Stamm L, Roth FP, Ambros V and Walhout AJM. (2008). A C. elegans genome-scale microRNA network contains composite feedback loops with high flux capacity. Genes Dev., 22:2535-49.

Leonard D, Hayakawa A, Lawe D, Lambright D, Bellve KD, Standley C, Lifshitz LM, Fogarty KE, Corvera S. (2008). Sorting of EGF and transferrin at the plasma membrane and by cargo-specific signaling to EEA1-enriched endosomes. J Cell Sci. 121:3445-58.

Follit JA, SanAgustin JT, Xu F, Jonassen J, and Pazour GJ. (2008). The golgin GMAP210/TRIP11 anchors IFT20 to the Golgi complex. PLoS Genetics. 4:e1000315.

Christianson JL, Nicoloro S, Straubhaar J, Czech MP. (2008). Stearoyl-CoA desaturase 2 is required for peroxisome proliferator-activated receptor gamma expression and adipogenesis in cultured 3T3-L1 cells. J Biol Chem. 283:2906-16.

Kundu, S., Horn, P.J., and Peterson, C.L. (2007). SWI/SNF is required for transcriptional memory at the GAL1 gene cluster. Genes Dev., 21:997-1004.

DiNitto, J., Delprato, A., Lee, M.-T., Cronin, T., Huang, Guilherme, A., S., Czech, M. P., & Lambright, D. G. (2007) Structural Basis and Mechanism of Autoregulation in 3-Phosphoinositide Dependent Grp1 Family Arf GTPase Exchange Factors, Mol. Cell 28:569-583.

Fonseca, S.G., Lipson, K.L., and Urano, F. (2007). Endoplasmic reticulum stress signaling in pancreatic beta cells. Antioxid Redox Signal, 9: 2335-44.

Yang, X., Zaurin, R., Beato, M., and Peterson, C.L. (2007). Swi3p controls SWI/SNF assembly and histone H2A/H2B dimer displacement. Nat. Struct. Mol. Biol., 14:540-547.

Klattenhoff C, Bratu DP, McGinnis-Schultz N, Koppetsch BS, Cook HA, Theurkauf WE. (2007). Drosophila rasiRNA pathway mutations disrupt embryonic axis specification through activation of an ATR/Chk2 DNA damage response. Dev Cell. 12:45-55.

Hayakawa A, Hayes S, Leonard D, Lambright D, Corvera S. (2007). Evolutionarily conserved structural and functional roles of the FYVE domain. Biochem Soc Symp. 74:95-105.

Padmanabhan, K., Richter, J.D. (2006). Regulated Pumilio-2 binding controls RINGO/Spy mRNA translation and CPEB activation. Genes Dev. 20:199-209.

Hayakawa A, Leonard D, Murphy S, Hayes S, Soto M, Fogarty K, Standley C, Bellve K, Lambright D, Mello C, Corvera S. (2006). The WD40 and FYVE domain containing protein 2 defines a class of early endosomes necessary for endocytosis. Proc Natl Acad Sci U S A. 103:11928-33.

Rosa J, Canovas P, Islam A, Altieri DC, Doxsey SJ. (2006). Survivin modulates microtubule dynamics and nucleation throughout the cell cycle. Mol Biol Cell. 17:1483-93.

Lipson, K.L., Fonseca, S.G., Ishigaki, S., Nguyen, L.X., Foss, E., Bortell, R., Rossini, A.A., and Urano, F. (2006). Regulation of insulin biosynthesis in pancreatic beta cells by an endoplasmic reticulum-resident protein kinase IRE1. Cell Metabolism, 4: 245-254.

Heilman SA, Kuo YH, Goudswaard CS, Valk PJ, Castilla LH. (2006). Cbfbeta reduces Cbfbeta-SMMHC-associated acute myeloid leukemia in mice. Cancer Res. 66:11214-8.

Deplancke B, Mukhopadhyay A, Ao W, Elewa AE, Grove CA, Martinez NJ, Sequerra R, Doucette-Stamm L, Reece-Hoyes JS, Hope IA, Tissenbaum HA, Mango SE, Walhout AJM (2006). A gene-centered C. elegans protein-DNA interaction network. Cell, 125:1193-1205.

Duchaine, T.F., Wohlschlegel, J.A., Kennedy, S., Bei, Y., Conte, D., Pang, K-M., Brownell, D.R., Harding, S., Mitani, S., Ruvkun, G., Yates, J.R. Mello, C.C. (2006) Functional proteomics reveals the biochemical niche of C. elegans DCR-1 in multiple small-RNA-mediated pathways. Cell 124:343-54. PMID 16439208.

Yigit, Y., Batista, P.J., Bei, Y., Pang, K-M., Chen, C-C.G., Tolia, N.H., Joshua-Tor, L., Mitani, S., Simard, M.J., Mello, C.C. (2006) Analysis of the C. elegans Argonaute family reveals that distinct Argonautes Act Sequentially During RNAi. Cell 127:747-757. PMID 17110334.

Ganguly, A. Jiang, J., and Ip, Y. T. (2005) Drosophila WntD is a target and an inhibitor of the Dorsal/Twist/Snail network in the gastrulating embryo. Development 132: 3419-3429.

Yu Z, Sánchez-Velar N, Catrina IE, Kittler EL, Udofia EB, Zapp ML. (2005). The cellular HIV-1 Rev cofactor hRIP is required for viral replication. Proc Natl Acad Sci U S A. 102:4027-32.

Brancho, D., Ventura, J-J. Jaeschke, A., Flavell, R. A., and Davis, R. J. (2005). Role of MLK3 in the regulation of MAP kinase signaling cascades. Mol. Cell. Biol. 25:3670-81.

Cronin, T. C., DiNitto, J. P., Czech, M. P., & Lambright, D. G. (2004) Structural determinants of phosphoinositide selectivity in splice variants of Grp1 family PH domains, EMBO J. 23:3711-3720.

Sarkissian, M., Mendez, R., Richter, J.D. (2004). Progesterone and insulin stimulation of CPEB-dependent polyadenylation is regulated by Aurora A and glycogen synthase kinase-3. Genes Dev. 18:48-61.

Ashraf, S. I., Ganguly, A., Roote, J. and Ip, Y. T. (2004) Worniu, a Snail family zinc-finger protein, is required for brain development in Drosophila. Developmental Dynamics, 231: 379-386.