What is Clinical and Translational Research?
Clinical research is defined by the NIH as
- Patient-oriented research. Research conducted with human subjects (or on material of human origin such as tissues, specimens and cognitive phenomena) for which an investigator directly interacts with human subjects. Patient-oriented research includes:
- mechanisms of human disease,
- therapeutic interventions,
- clinical trials, or
- development of new technologies.
- Epidemiological and behavioral studies.
- Outcomes research and health services research.
Translational research is defined by NIH as
- The process of applying discoveries generated during basic research in the laboratory, and in preclinical studies, to the development of trials and studies in humans.
- Research aimed at enhancing the adoption of best practices in the community. Cost-effectiveness of prevention and treatment strategies is an important part of translational science.