Our mission is to develop diagnostic and theranostic contrast agents and sensing probes capable of detecting/treating human disease at its earliest stage. We focus on applying both well-established and emerging cross-sectional in vivo imaging modalities (magnetic resonance imaging, photoacoustic, fluorescence lifetime tomographies) to detect and measure real-time, molecular-level physiological events.
Our current projects include (1) Imaging in CVA Models, (2) Transcription Factor Imaging Probes, (3) Imaging of adoptive cell transfer and (4) Enzyme-sensing Magnetic Resonance Imaging.
The Laboratory of Molecular Imaging probes has about 20 years of experience in the field of in vivo molecular imaging. We perform fee-for-service development of small molecules and nanoparticles designed for optical, photoacoustic and MR imaging. The latter include both paramagnetic and superparamagnetic imaging probes. We are also equipped to perform purification, formulation and initial testing in vitro and in vivo.